巴林王国的人类免疫缺陷病毒感染和化疗治疗

J. A. Salman, R. Agha, E. Fareed, L. Ali, K. Nasser, Zainab Al Sikri, Rehab Al Noaimi
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摘要

人类免疫缺陷病毒(HIV)是一种慢病毒,可发展为免疫缺陷综合征(艾滋病),易发生机会性感染和恶性肿瘤。根据最近的报告,2013年全世界有150万人死于艾滋病,比2005年减少了35%。死亡人数减少的部分原因是抗逆转录病毒治疗的广泛使用。2011年,巴林成立了一个多学科艾滋病毒管理小组,主要利益攸关方包括:公共卫生、传染病、药剂师、护理和病毒学家。对巴林的艾滋病毒阳性患者进行了回顾性描述性研究,收集了他们目前的治疗方案和其他血液参数,目的是对他们的健康状况有一个大致的了解,以帮助他们的医疗护理。这些数据是从2014年所有被诊断患有艾滋病毒的患者的登记册中回顾性收集的。收集患者的ART治疗方案、cd4计数和病毒载量,并将其录入Excel表格。截至2014年,共有208名患者被诊断患有艾滋病毒。然而,其中只有108家拥有完整的数据。此外,对这些患者在10年期间的入院频率也进行了回顾。回顾2004年至2014年近10年入院患者的病历,发现HIV阳性患者入院总数为107例。丙型肝炎是这些患者中最常见的合并感染,占24%。我们发现,随着抗逆转录病毒治疗的改善和HIV团队和项目结构的改善,我们正在控制更多的患者。CD4细胞计数改善的患者数量明显增加。根据我们的研究结果,HIV多学科管理团队是对这些患者进行最佳管理的重要组成部分。
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Human immunodeficiency virus infection and chemotherapy treatment in the Kingdom of Bahrain
Human immunodeficiency virus (HIV) is a lentivirus which that may progress to immunodeficiency syndrome (AIDS) and predispose for opportunistic infections and malignancies. According to recent reports,  1.5 million people died of AIDS in 2013 worldwide which is a 35% decrease since 2005. The number of deaths has decreased in part due to antiretroviral treatment (ART) wide spread use. In Bahrain, in 2011, a multidisciplinary team was established for HIV management involving major stakeholders: public health, infectious diseases, pharmacists, nursing and virologists. A retrospective descriptive study is done about HIV positive patient in Bahrain, their current treatment regimens and other blood parameters were collected, aiming to have a general idea about their health status in a way to help in their medical care. The data was collected retrospectively from the 2014 registry about all patients who are diagnosed to have HIV. Their ART regimen, CD 4 count and viral load were gathered and entered in Excel sheet.. A total of 208 patients were diagnosed to have HIV up to 2014. However, only 108 of them have their full data. In addition, a review of the frequency of admission of these patients over a 10 year period was done too. On reviewing the medical records of the patients admitted over the last ten years from 2004 till 2014, it was found that the total admission of HIV positive patients were 107. Hepatitis C was the most common co infection among those patients with a percentage of 24%. It was found that with better ART treatment and better structure of HIV team and program, we are getting more patients to be controlled. There is a clear increase in the number of patients with improving CD4 count. Based on the results of our study, the HIV multi-disciplinary management team is an essential part for the best management of these patients.
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