现代旋转铰链假体全膝关节置换术的远期疗效

Umberto Cottino, M. Abdel, K. Perry, K. Mara, D. Lewallen, A. Hanssen
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引用次数: 84

摘要

背景:全膝关节置换术(TKA)与旋转铰链假体被认为是一种抢救手术。虽然实现了优异的即时稳定性,但历史上的高故障率降低了它的使用。本研究的目的是确定采用现代旋转铰链组件的TKA后的临床结果、影像学结果和生存率。方法:从2002年到2012年,我们在一个学术机构连续408例使用旋转铰链组件进行非肿瘤适应症tka。264例膝关节(65%)因无菌原因植入了旋转铰链TKA组件,144例膝关节(35%)在感染后进行了2期再植。74例膝关节(18%)使用旋转铰链TKA植入物进行复杂的初级手术,334例膝关节(82%)使用旋转铰链TKA植入物进行翻修。临床结果通过膝关节学会评分系统、生存分析和翻修的累积发生率进行评估。患者在关节置换术时的平均年龄为69岁,平均随访时间为4年(范围2至12年)。结果:在最近的随访中,膝关节协会的平均膝关节评分从术前51分增加到81分(p < 0.0001),膝关节协会的平均功能评分从26分增加到36分(p < 0.0001)。平均4年,349个膝关节中有13个(3.7%)出现膝关节构件松动。在最近的随访中,进行了59例翻修手术和25例再手术。任何翻修的累积发生率在2年时为9.7%,在10年时为22.5%。无菌性松动翻修的累积发生率在2年为1.7%,在10年为4.5%。114个膝关节(28%)使用了干骺端锥。生存分析显示修订的风险有降低的趋势(风险比[HR] = 0.69;95%置信区间[CI] = 0.39 ~ 1.22;p = 0.20)和再手术(HR = 0.51;95% CI = 0.22 ~ 1.19;P = 0.12),尽管它们用于最严重的骨缺损。结论:当代旋转铰链TKA种植体无菌性松动的10年累积翻修率较低,为4.5%。更多地使用干骺端固定有助于这种改善。患者可以期望通过这种修订策略在临床结果上有实质性的改善。证据等级:治疗性IV级。完整的证据等级描述见作者指南。
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Long-Term Results After Total Knee Arthroplasty with Contemporary Rotating-Hinge Prostheses
Background: Total knee arthroplasty (TKA) with a rotating-hinge prosthesis is considered a salvage procedure. While excellent immediate stability is achieved, the historically high failure rate has tempered its use. The goal of this study was to determine clinical outcomes, radiographic results, and survivorship after TKA with contemporary rotating-hinge components. Methods: We identified 408 consecutive TKAs performed with rotating-hinge components for nononcologic indications from 2002 to 2012 at a single academic institution. Two hundred and sixty-four knees (65%) had rotating-hinge TKA components implanted for aseptic etiologies, while 144 knees (35%) were managed with the components in 2-stage reimplantation following infection. Rotating-hinge TKA implants were used for complex primary procedures in 74 knees (18%) and as a revision construct in 334 knees (82%). Clinical outcomes were assessed with the Knee Society scoring system, survivorship analyses, and cumulative incidence of revision. The mean age of the patients at the time of the index arthroplasty was 69 years, and the mean duration of follow-up was 4 years (range, 2 to 12 years). Results: At the most recent follow-up, the mean Knee Society knee score had increased from 51 points preoperatively to 81 points (p < 0.0001), and the mean Knee Society functional score had increased from 26 to 36 points (p < 0.0001). At a mean of 4 years, loosening of components was observed in 13 (3.7%) of 349 knees. At the most recent follow-up, 59 revision procedures and 25 reoperations had been performed. The cumulative incidence of any revision was 9.7% at 2 years and 22.5% at 10 years. The cumulative incidence of revision for aseptic loosening was 1.7% at 2 years and 4.5% at 10 years. Metaphyseal cones were used in 114 knees (28%). Survivorship analysis revealed a trend toward a lower risk of revision (hazard ratio [HR] = 0.69; 95% confidence interval [CI] = 0.39 to 1.22; p = 0.20) and reoperation (HR = 0.51; 95% CI = 0.22 to 1.19; p = 0.12) in patients with metaphyseal cones, despite their use in the most severe of bone defects. Conclusions: Contemporary rotating-hinge TKA implants had a low 10-year cumulative incidence of revision for aseptic loosening of 4.5%. Greater use of metaphyseal fixation has aided this improvement. Patients can expect substantial improvements in clinical outcomes with this revision strategy. Level of Evidence: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
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