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A Prospective, Longitudinal Study of the Influence of Obesity on Total Knee Arthroplasty Revision Rate 肥胖症对全膝关节置换术翻修率影响的前瞻性、纵向研究
Pub Date : 2022-06-16 DOI: 10.2106/JBJS.21.01491
C. J. Wall, C. Vertullo, S. Kondalsamy-Chennakesavan, M. Lorimer, R. D. de Steiger
Background: The aim of this study was to investigate the relationship of obesity with all-cause revision and revision for infection, loosening, instability, and pain after total knee arthroplasty (TKA) performed in Australia. Methods: Data for patients undergoing primary TKA for osteoarthritis from January 1, 2015, to December 31, 2020, were obtained from the Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR). The rates of all-cause revision and revision for infection, loosening, instability, and pain were compared for non-obese patients (body mass index [BMI], 18.50 to 29.99 kg/m2), class-I and II obese patients (BMI, 30.00 to 39.99 kg/m2), and class-III obese patients (BMI, ≥40.00 kg/m2). The results were adjusted for age, sex, tibial fixation, prosthesis stability, patellar component usage, and computer navigation usage. Results: During the study period, 141,673 patients underwent primary TKA for osteoarthritis in Australia; of these patients, 48.0% were class-I or II obese, and 10.6% were class-III obese. The mean age was 68.2 years, and 54.7% of patients were female. The mean follow-up period was 2.8 years. Of the 2,655 revision procedures identified, the reasons for the procedures included infection in 39.7%, loosening in 14.8%, instability in 12.0%, and pain in 6.1%. Class-I and II obese patients had a higher risk of all-cause revision (hazard ratio [HR], 1.12 [95% confidence interval (CI), 1.03 to 1.22]; p = 0.007) and revision for infection (HR, 1.25 [95% CI, 1.10 to 1.43]; p = 0.001) than non-obese patients. Class-III obese patients had a higher risk of all-cause revision after 1 year (HR, 1.30 [95% CI, 1.14 to 1.52]; p < 0.001), revision for infection after 3 months (HR, 1.72 [95% CI, 1.33 to 2.17]; p < 0.001), and revision for loosening (HR, 1.39 [95% CI, 1.00 to 1.89]; p = 0.047) than non-obese patients. The risks of revision for instability and pain were similar among groups. Conclusions: Obese patients with knee osteoarthritis should be counseled with regard to the increased risks associated with TKA, so they can make informed decisions about their health care. Health services and policymakers need to address the issue of obesity at a population level. Level of Evidence: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
背景:本研究的目的是调查肥胖与全因翻修的关系,以及在澳大利亚进行全膝关节置换术(TKA)后感染、松动、不稳定和疼痛的翻修。方法:2015年1月1日至2020年12月31日期间接受骨关节炎原发性TKA患者的数据来自澳大利亚骨科协会国家关节置换登记处(AOANJRR)。比较非肥胖患者(体重指数[BMI], 18.50 ~ 29.99 kg/m2)、i级和II级肥胖患者(体重指数,30.00 ~ 39.99 kg/m2)和iii级肥胖患者(体重指数,≥40.00 kg/m2)的全因翻修率和感染、松动、不稳定和疼痛翻修率。结果根据年龄、性别、胫骨固定、假体稳定性、髌骨假体使用情况和计算机导航使用情况进行调整。结果:在研究期间,澳大利亚有141673例患者接受了原发性骨关节炎TKA;其中,ⅰ、ⅱ类肥胖占48.0%,ⅲ类肥胖占10.6%。平均年龄68.2岁,女性占54.7%。平均随访时间为2.8年。在确定的2655例翻修手术中,手术原因包括感染(39.7%)、松动(14.8%)、不稳定(12.0%)和疼痛(6.1%)。i级和II级肥胖患者发生全因修正的风险较高(风险比[HR], 1.12[95%可信区间(CI), 1.03 ~ 1.22];p = 0.007)和修改感染(HR, 1.25 [95% CI, 1.10 ~ 1.43];P = 0.001)。iii级肥胖患者1年后发生全因翻修的风险较高(HR, 1.30 [95% CI, 1.14 ~ 1.52];p < 0.001), 3个月后复查感染(HR, 1.72 [95% CI, 1.33 ~ 2.17];p < 0.001),针对松动进行修正(HR, 1.39 [95% CI, 1.00 - 1.89];P = 0.047)。各组间不稳定和疼痛的翻修风险相似。结论:应告知肥胖膝骨关节炎患者TKA相关的风险增加,以便他们做出明智的医疗保健决定。卫生服务机构和决策者需要在人口层面解决肥胖问题。证据等级:预后III级。有关证据水平的完整描述,请参见作者说明。
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引用次数: 8
A Comparison of Revision Rates and Dislocation After Primary Total Hip Arthroplasty with 28, 32, and 36-mm Femoral Heads and Different Cup Sizes 28、32、36 mm不同罩杯股骨头初次全髋关节置换术后复位率及脱位的比较
Pub Date : 2022-06-16 DOI: 10.2106/JBJS.21.01101
W. Hoskins, Sophia Rainbird, C. Holder, J. Stoney, S. Graves, R. Bingham
Update This article was updated on August 17, 2022, because of previous errors, which were discovered after the preliminary version of the article was posted online. On page 1462, in the first sentence of the Abstract section entitled “Results,” the phrase that had read “and 36-mm heads had fewer dislocations than 28-mm (HR = 0.33 [95% CI, 0.16 to 0.68]; p = 0.003), but more dislocations than 32-mm heads (HR for >2 weeks = 2.25 [95% CI, 1.13 to 4.49]; p = 0.021)” now reads “and 36-mm heads had fewer dislocations than 28-mm (HR = 0.33 [95% CI, 0.16 to 0.68]; p = 0.003) and 32-mm heads (HR for ≥2 weeks = 0.44 [95% CI, 0.22 to 0.88]; p = 0.021).” On page 1468, in the last sentence of the section entitled “Acetabular Components with a Diameter of <51 mm,” the phrase that had read “and HR for ≥2 weeks = 2.25 [95% CI, 1.13 to 4.49; p = 0.021]) (Fig. 3)” now reads “and HR for ≥2 weeks = 0.44 [95% CI, 0.22 to 0.88; p = 0.021]) (Fig. 3).” Finally, on page 1466, in the upper right corner of Figure 3, under “32mm vs 36mm,” the second line that had read “2Wks+: HR=2.25 (1.13, 4.49), p=0.021” now reads “2Wks+: HR=0.44 (0.22, 0.88), p= 0.021.” Background: The acetabular component diameter can influence the choice of femoral head size in total hip arthroplasty (THA). We compared the rates of revision by femoral head size for different acetabular component sizes. Methods: Data from the Australian Orthopaedic Association National Joint Replacement Registry were analyzed for patients undergoing primary THA for a diagnosis of osteoarthritis from September 1999 to December 2019. Acetabular components were stratified into quartiles by size: <51 mm, 51 to 53 mm, 54 to 55 mm, and 56 to 66 mm. Femoral head sizes of 28 mm, 32 mm, and 36 mm were compared for each cup size. The primary outcome was the cumulative percent revision (CPR) for all aseptic causes and for dislocation. The results were adjusted for age, sex, femoral fixation, femoral head material, year of surgery, and surgical approach and were stratified by femoral head material. Results: For acetabular components of <51 mm, 32-mm (hazard ratio [HR] = 0.75 [95% confidence interval (CI), 0.57 to 0.97]; p = 0.031) and 36-mm femoral heads (HR = 0.58 [95% CI, 0.38 to 0.87]; p = 0.008) had a lower CPR for aseptic causes than 28-mm heads; and 36-mm heads had fewer dislocations than 28-mm (HR = 0.33 [95% CI, 0.16 to 0.68]; p = 0.003), and 32-mm heads (HR for ≥2 weeks = 0.44 [95% CI, 0.22 to 0.88]; p = 0.021). For 51 to 53-mm, 54 to 55-mm, and 56 to 66-mm-diameter acetabular components, there was no difference in the CPR for aseptic causes among head sizes. A femoral head size of 36 mm had fewer dislocations in the first 2 weeks than a 32-mm head for the 51 to 53-mm acetabular components (HR for <2 weeks = 3.79 [95% CI, 1.23 to 11.67]; p = 0.020) and for the entire period for 56 to 66-mm acetabular components (HR = 1.53 [95% CI, 1.05 to 2.23]; p = 0.028). The reasons for revision differed for each femoral head size. The
由于之前的错误,本文于2022年8月17日更新,这些错误是在文章的初步版本发布到网上后发现的。在第1462页,标题为“结果”的摘要部分的第一句话中,“和36毫米的头比28毫米的头有更少的脱位(HR = 0.33 [95% CI, 0.16至0.68];p = 0.003),但脱位多于32毫米头(HR >2周= 2.25 [95% CI, 1.13 ~ 4.49];p = 0.021)“now reads”和36-mm头的脱位少于28-mm (HR = 0.33 [95% CI, 0.16至0.68];p = 0.003)和32毫米头(HR≥2周= 0.44 [95% CI, 0.22 ~ 0.88];P = 0.021)。在第1468页,题为“直径<51 mm的髋臼组件”部分的最后一句话中,有这样的短语:and HR for≥2周= 2.25 [95% CI, 1.13 ~ 4.49;p = 0.021])(图3)“now reads”和HR≥2周= 0.44 [95% CI, 0.22 ~ 0.88;最后,在第1466页,在图3的右上角,“32mm vs 36mm”下面,第二行原来是“2Wks+: HR=2.25 (1.13, 4.49), p=0.021”,现在变成了“2Wks+: HR=0.44 (0.22, 0.88), p=0.021”。背景:髋臼假体直径可影响全髋关节置换术中股骨头大小的选择。我们比较了不同髋臼假体大小的股骨头大小的翻修率。方法:分析1999年9月至2019年12月期间澳大利亚骨科协会国家关节置换登记处的数据,这些数据来自于诊断为骨关节炎的原发性THA患者。髋臼组件按尺寸分为四分位数:<51 mm、51 ~ 53 mm、54 ~ 55 mm和56 ~ 66 mm。不同罩杯的股骨头尺寸分别为28mm、32mm和36mm。主要结果是所有无菌原因和脱位的累积百分比修正(CPR)。结果根据年龄、性别、股骨固定、股骨头材料、手术年份和手术入路进行调整,并按股骨头材料分层。结果:对于髋臼假体<51 mm、32 mm(风险比[HR] = 0.75[95%可信区间(CI), 0.57 ~ 0.97];p = 0.031)和36-mm股骨头(HR = 0.58 [95% CI, 0.38 ~ 0.87];p = 0.008)无菌原因的CPR低于28毫米头部;36-mm头的脱位比28-mm头少(HR = 0.33 [95% CI, 0.16 ~ 0.68];p = 0.003), 32毫米头(HR≥2周= 0.44 [95% CI, 0.22 ~ 0.88];P = 0.021)。对于51 ~ 53 mm、54 ~ 55 mm和56 ~ 66 mm直径的髋臼组件,不同头部尺寸的无菌原因的CPR无差异。对于51 ~ 53 mm的髋臼假体,36 mm股骨头比32 mm股骨头在前2周发生的脱位更少(HR <2周= 3.79 [95% CI, 1.23 ~ 11.67];p = 0.020), 56 ~ 66 mm髋臼假体的整个周期(HR = 1.53 [95% CI, 1.05 ~ 2.23];P = 0.028)。股骨头大小不同,翻修的原因也不同。金属头和陶瓷头的心肺复苏术没有差别。结论:除了髋臼假体<51 mm外,任何单一股骨头尺寸都没有明显的优势,其中32 mm和36 mm股骨头的无菌翻修率较低。如果优先考虑稳定性,可能需要36mm股骨头。证据等级:治疗性III级。有关证据水平的完整描述,请参见作者说明。
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引用次数: 7
In Adults Aged <65 Years with Unstable Ankle Fractures, Fibular Nailing Did Not Differ from Open Reduction and Internal Fixation for Functional Outcome at 1 Year 对于年龄<65岁的不稳定踝关节骨折患者,腓骨内钉与切开复位和内固定在1年内的功能结果没有差异
Pub Date : 2022-06-06 DOI: 10.2106/JBJS.22.00486
P. Grimm
Patients: 125 patients aged 18 to 64 years (mean age, 42 years; 50%women)who had an ankle fracture within the past 2 weeks that was unstable as indicated by talar displacement on ankle radiographs at presentation or at 1 week after injury. Exclusion criteria included bilateral injuries, ipsilateral lower-limb injury, pilon fractures, or ankle fractures not requiring lateral fixation. 88% of patients completed follow-up at 1 year and 79%at 2 years.
患者:125例患者,年龄18 ~ 64岁(平均年龄42岁;(50%女性),在过去2周内发生踝关节骨折,在就诊时或受伤后1周的踝关节x线片上显示距骨移位不稳定。排除标准包括双侧损伤、同侧下肢损伤、皮隆骨折或不需要外侧固定的踝关节骨折。88%的患者在1年完成随访,79%的患者在2年完成随访。
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引用次数: 0
In Single-Bundle ACL Reconstruction Using Patellar Tendon Autograft, Knee Flexion Angle of 0° Versus 30° During Tibial ACL Graft Fixation Did Not Differ for KOOS Subscales, but Improved Activity Level 在自体髌骨肌腱单束前交叉韧带重建中,膝关节屈曲角度为0°与30°的胫骨前交叉韧带固定在kos亚量表上没有差异,但活动水平有所提高
Pub Date : 2022-06-03 DOI: 10.2106/JBJS.22.00485
N. Marom
patellar tendon autograft fi xation at 0 (cid:1) versus 30 (cid:1) results in improved activity scores and a greater proportion of patients achieving the MCID for KOOS pain: a randomized controlled trial.
在一项随机对照试验中,0 (cid:1)与30 (cid:1)的髌骨肌腱自体移植物固定可以改善活动评分,并且更大比例的患者达到oos疼痛的MCID。
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引用次数: 0
In Patients with Displaced Type-II Distal Clavicle Fractures, Operative and Nonoperative Therapies Did Not Differ for Functional Outcomes at 1 Year 在移位型ii型锁骨远端骨折患者中,手术和非手术治疗在1年的功能结局上没有差异
Pub Date : 2022-06-02 DOI: 10.2106/JBJS.22.00484
N. Chen
Main outcomemeasures: The primary outcome was theDisabilities of the Arm, Shoulder andHand score at 1 year. Secondary outcomes included Constant-Murley score, visual analogue scale pain score, patient satisfaction, return to work and sports, union, and adverse events at 1 year. Main results: The main results at 1 year are in Table I. There were 2 adverse events in the operative group and 4 in the nonoperative group.
主要观察指标:主要观察指标为1年时手臂、肩部和手部残疾评分。次要结局包括Constant-Murley评分、视觉模拟疼痛评分、患者满意度、恢复工作和运动、工会和1年不良事件。主要结果:1年主要结果见表1。手术组不良事件2例,非手术组4例。
{"title":"In Patients with Displaced Type-II Distal Clavicle Fractures, Operative and Nonoperative Therapies Did Not Differ for Functional Outcomes at 1 Year","authors":"N. Chen","doi":"10.2106/JBJS.22.00484","DOIUrl":"https://doi.org/10.2106/JBJS.22.00484","url":null,"abstract":"Main outcomemeasures: The primary outcome was theDisabilities of the Arm, Shoulder andHand score at 1 year. Secondary outcomes included Constant-Murley score, visual analogue scale pain score, patient satisfaction, return to work and sports, union, and adverse events at 1 year. Main results: The main results at 1 year are in Table I. There were 2 adverse events in the operative group and 4 in the nonoperative group.","PeriodicalId":22579,"journal":{"name":"The Journal of Bone and Joint Surgery","volume":"12 1","pages":"1503 - 1503"},"PeriodicalIF":0.0,"publicationDate":"2022-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89908712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Total Hip Arthroplasty Leads to Better Results After Low-Energy Displaced Femoral Neck Fracture in Patients Aged 55 to 70 Years 55 ~ 70岁低能量移位型股骨颈骨折患者行全髋关节置换术效果较好
Pub Date : 2022-05-31 DOI: 10.2106/JBJS.21.01411
S. Bartels, Torbjørn B. Kristensen, J. Gjertsen, F. Frihagen, C. Rogmark, Filip C. Dolatowski, W. Figved, J. Benth, S. E. Utvåg
Background: The optimal treatment of displaced femoral neck fractures in patients 55 to 70 years old remains controversial. The aim of the present study was to assess the effect of closed reduction and internal fixation with cannulated screws (IF) compared with total hip arthroplasty (THA) on hip pain and function, with use of data for outcome measures, complications, and reoperations. Methods: This multicenter randomized controlled trial included all patients 55 to 70 years old who presented with a low-energy displaced femoral neck fracture between December 2013 and December 2018. Patients were randomly allocated to undergo either IF or THA. The primary outcome was the Harris Hip Score (HHS) at 12 months postoperatively. Secondary outcomes were the HHS at 4 and 24 months postoperatively, Oxford Hip Score (OHS), Hip Disability and Osteoarthritis Outcome Score (HOOS), health-related quality of life (EQ-5D-3L [EuroQol 5 Dimensions 3 Levels] index score and EQ-VAS [visual analogue scale]), VAS for pain, and VAS for patient satisfaction at 4, 12, and 24 months postoperatively. Complications and reoperations were continuously monitored. The primary analyses were performed according to the intention-to-treat principle. Results: A total of 102 patients with a mean (± standard deviation) age of 63.7 ± 4.2 years were allocated to IF (n = 51) or THA (n = 51). The mean difference in the primary outcome, the HHS at 12 months postoperatively (5.3; 95% confidence interval, 0.9 to 9.7; p = 0.017), was below the predefined minimal clinically important difference of 10 points. However, patients who underwent THA had a significantly higher HHS at 4 and 12 months, better OHS at 4 and 12 months, and better HOOS at 4, 12, and 24 months postoperatively. Patients who underwent THA also reported better health-related quality of life at 4 months postoperatively and reported greater satisfaction and less pain at 4 and 12 months postoperatively. A total of 26 patients in the IF group (51%; 95% confidence interval, 37% to 65%) and 2 patients in the THA group (4%; 95% confidence interval, 0.5% to 13%) underwent a major reoperation. Conclusions: In this randomized controlled trial, we showed that patients between 55 and 70 years old who underwent THA for a low-energy displaced femoral neck fracture experienced better outcomes than those who underwent closed reduction and internal fixation. Level of Evidence: Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.
背景:55 ~ 70岁患者移位性股骨颈骨折的最佳治疗方法仍存在争议。本研究的目的是评估闭合复位和空心螺钉内固定(IF)与全髋关节置换术(THA)对髋关节疼痛和功能的影响,并使用结果测量、并发症和再手术的数据。方法:这项多中心随机对照试验纳入了2013年12月至2018年12月期间出现低能移位性股骨颈骨折的所有55至70岁患者。患者被随机分配接受IF或THA。主要结果是术后12个月Harris髋关节评分(HHS)。次要结果是术后4个月和24个月的HHS、牛津髋关节评分(OHS)、髋关节残疾和骨关节炎结局评分(HOOS)、健康相关生活质量(EQ-5D-3L [EuroQol 5维3水平]指数评分和EQ-VAS[视觉模拟量表])、疼痛VAS评分和术后4、12和24个月的患者满意度VAS评分。持续监测并发症及再手术情况。根据意向治疗原则进行初步分析。结果:共有102例患者(平均(±标准差)年龄为63.7±4.2岁)被分配到IF (n = 51)或THA (n = 51)组。主要转归的平均差异,术后12个月HHS (5.3;95%置信区间为0.9 ~ 9.7;P = 0.017),低于预定的最小临床重要差异10分。然而,接受THA的患者在术后4个月和12个月的HHS明显较高,4个月和12个月的OHS较好,术后4个月、12个月和24个月的HOOS较好。接受THA的患者在术后4个月也报告了更好的健康相关生活质量,并在术后4个月和12个月报告了更高的满意度和更少的疼痛。IF组共有26例患者(51%;95%可信区间,37% ~ 65%),THA组2例(4%;95%可信区间,0.5%至13%)接受了主要的再手术。结论:在这项随机对照试验中,我们发现55 - 70岁的低能量移位型股骨颈骨折患者行THA治疗比行闭合复位内固定治疗效果更好。证据水平:治疗性i级。参见《作者说明》获得证据水平的完整描述。
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引用次数: 1
Pain Catastrophizing Predicts Opioid and Health-Care Utilization After Orthopaedic Surgery 疼痛灾难预测骨科手术后阿片类药物和医疗保健使用
Pub Date : 2022-05-27 DOI: 10.2106/JBJS.22.00177
D. Rhon, Tina A. Greenlee, Patricia K. Carreño, Jeanne C. Patzkowski, K. Highland
Background: Most individuals undergoing elective surgery expect to discontinue opioid use after surgery, but many do not. Modifiable risk factors including psychosocial factors are associated with poor postsurgical outcomes. We wanted to know whether pain catastrophizing is specifically associated with postsurgical opioid and health-care use. Methods: This was a longitudinal cohort study of trial participants undergoing elective spine (lumbar or cervical) or lower-extremity (hip or knee osteoarthritis) surgery between 2015 and 2018. Primary and secondary outcomes were 12-month postsurgical days’ supply of opioids and surgery-related health-care utilization, respectively. Self-reported and medical record data included presurgical Pain Catastrophizing Scale (PCS) scores, surgical success expectations, opioid use, and pain interference duration. Results: Complete outcomes were analyzed for 240 participants with a median age of 42 years (34% were female, and 56% were active-duty military service members). In the multivariable generalized additive model, greater presurgical days’ supply of opioids (F = 17.23, p < 0.001), higher pain catastrophizing (F = 1.89, p = 0.004), spine versus lower-extremity surgery (coefficient estimate = 1.66 [95% confidence interval (CI), 0.50 to 2.82]; p = 0.005), and female relative to male sex (coefficient estimate = −1.25 [95% CI, −2.38 to −0.12]; p = 0.03) were associated with greater 12-month postsurgical days’ supply of opioids. Presurgical opioid days’ supply (chi-square = 111.95; p < 0.001), pain catastrophizing (chi-square = 96.06; p < 0.001), and lower extremity surgery (coefficient estimate = −0.17 [95% CI, −0.24 to −0.11]; p < 0.001), in addition to age (chi-square = 344.60; p < 0.001), expected recovery after surgery (chi-square = 54.44; p < 0.001), active-duty status (coefficient estimate = 0.58 [95% CI, 0.49 to 0.67]; p < 0.001), and pain interference duration (chi-square = 43.47; p < 0.001) were associated with greater health-care utilization. Conclusions: Greater presurgical days’ supply of opioids and pain catastrophizing accounted for greater postsurgical days’ supply of opioids and health-care utilization. Consideration of several modifiable factors provides an opportunity to improve postsurgical outcomes. Level of Evidence: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
背景:大多数接受选择性手术的个体期望在手术后停止使用阿片类药物,但许多人没有。包括社会心理因素在内的可改变的危险因素与术后不良预后相关。我们想知道疼痛灾难化是否与术后阿片类药物和医疗保健使用特别相关。方法:这是一项纵向队列研究,研究对象是2015年至2018年间接受选择性脊柱(腰椎或颈椎)或下肢(髋关节或膝关节骨关节炎)手术的试验参与者。主要和次要结局分别是术后12个月阿片类药物的供应和手术相关保健的利用。自我报告和医疗记录数据包括手术前疼痛灾难量表(PCS)评分、手术成功预期、阿片类药物使用和疼痛干扰持续时间。结果:对240名中位年龄为42岁的参与者(34%为女性,56%为现役军人)的完整结果进行了分析。在多变量广义加性模型中,手术前阿片类药物供应天数更大(F = 17.23, p < 0.001),疼痛灾难化程度更高(F = 1.89, p = 0.004),脊柱手术与下肢手术(系数估计= 1.66[95%置信区间(CI), 0.50至2.82];p = 0.005),女性相对于男性(系数估计= - 1.25 [95% CI, - 2.38至- 0.12];P = 0.03)与术后12个月阿片类药物供应增加相关。手术前阿片类药物日供应量(卡方= 111.95;P < 0.001),疼痛灾难化(卡方= 96.06;p < 0.001),下肢手术(系数估计= - 0.17 [95% CI, - 0.24至- 0.11];P < 0.001),除年龄外(卡方= 344.60;P < 0.001),术后预期恢复(卡方= 54.44;p < 0.001)、现役状态(系数估计= 0.58 [95% CI, 0.49 ~ 0.67];P < 0.001),疼痛干扰持续时间(χ 2 = 43.47;P < 0.001)与较高的医疗保健利用率相关。结论:更多的术前阿片类药物供应和疼痛灾变是术后阿片类药物供应和医疗保健利用增加的原因。考虑几个可改变的因素提供了改善术后预后的机会。证据等级:预后III级。有关证据水平的完整描述,请参见作者说明。
{"title":"Pain Catastrophizing Predicts Opioid and Health-Care Utilization After Orthopaedic Surgery","authors":"D. Rhon, Tina A. Greenlee, Patricia K. Carreño, Jeanne C. Patzkowski, K. Highland","doi":"10.2106/JBJS.22.00177","DOIUrl":"https://doi.org/10.2106/JBJS.22.00177","url":null,"abstract":"Background: Most individuals undergoing elective surgery expect to discontinue opioid use after surgery, but many do not. Modifiable risk factors including psychosocial factors are associated with poor postsurgical outcomes. We wanted to know whether pain catastrophizing is specifically associated with postsurgical opioid and health-care use. Methods: This was a longitudinal cohort study of trial participants undergoing elective spine (lumbar or cervical) or lower-extremity (hip or knee osteoarthritis) surgery between 2015 and 2018. Primary and secondary outcomes were 12-month postsurgical days’ supply of opioids and surgery-related health-care utilization, respectively. Self-reported and medical record data included presurgical Pain Catastrophizing Scale (PCS) scores, surgical success expectations, opioid use, and pain interference duration. Results: Complete outcomes were analyzed for 240 participants with a median age of 42 years (34% were female, and 56% were active-duty military service members). In the multivariable generalized additive model, greater presurgical days’ supply of opioids (F = 17.23, p < 0.001), higher pain catastrophizing (F = 1.89, p = 0.004), spine versus lower-extremity surgery (coefficient estimate = 1.66 [95% confidence interval (CI), 0.50 to 2.82]; p = 0.005), and female relative to male sex (coefficient estimate = −1.25 [95% CI, −2.38 to −0.12]; p = 0.03) were associated with greater 12-month postsurgical days’ supply of opioids. Presurgical opioid days’ supply (chi-square = 111.95; p < 0.001), pain catastrophizing (chi-square = 96.06; p < 0.001), and lower extremity surgery (coefficient estimate = −0.17 [95% CI, −0.24 to −0.11]; p < 0.001), in addition to age (chi-square = 344.60; p < 0.001), expected recovery after surgery (chi-square = 54.44; p < 0.001), active-duty status (coefficient estimate = 0.58 [95% CI, 0.49 to 0.67]; p < 0.001), and pain interference duration (chi-square = 43.47; p < 0.001) were associated with greater health-care utilization. Conclusions: Greater presurgical days’ supply of opioids and pain catastrophizing accounted for greater postsurgical days’ supply of opioids and health-care utilization. Consideration of several modifiable factors provides an opportunity to improve postsurgical outcomes. Level of Evidence: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.","PeriodicalId":22579,"journal":{"name":"The Journal of Bone and Joint Surgery","volume":"48 1","pages":"1447 - 1454"},"PeriodicalIF":0.0,"publicationDate":"2022-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90642418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Aspirin May Be a Suitable Prophylaxis for Patients with a History of Venous Thromboembolism Undergoing Total Joint Arthroplasty 阿司匹林可能是一个合适的预防患者有静脉血栓栓塞史进行全关节置换术
Pub Date : 2022-05-26 DOI: 10.2106/JBJS.21.00601
Leanne Ludwick, N. Shohat, Duncan S Van Nest, J. Paladino, Jonathan Ledesma, J. Parvizi
Background: In recent years, aspirin has become a popular agent for venous thromboembolism (VTE) prophylaxis following total joint arthroplasty (TJA). Yet patients with a history of VTE are often given more aggressive prophylactic agents because of their increased baseline risk. The purpose of this study was to assess whether aspirin is an effective prophylactic agent in patients with a history of VTE. Methods: This was a single-institution, retrospective cohort study. The electronic clinical records of 36,333 patients undergoing TJA between 2008 and 2020 were reviewed. Data on demographic characteristics, comorbidities, intraoperative factors, and postoperative complications were collected. A propensity score-matched analysis was performed, as well as a multivariate regression analysis to account for confounders. Results: Of the 36,333 patients undergoing TJA, 1,087 patients (3.0%) had a history of VTE and were not receiving chronic non-aspirin. The risk for subsequent VTE was significantly higher (p = 0.03) in patients with a history of VTE (1.4%) compared with patients without prior VTE (0.9%). However, the incidence of VTE was not significantly lower (p = 0.208) in patients with a history of VTE who received aspirin (0.4%) compared with patients who received other VTE prophylaxis (1.5%). Propensity score matching showed no difference in VTE rates between the 2 groups (2.2% compared with 0.55%; p = 0.372). In a regression analysis accounting for VTE risk, the administration of aspirin was not associated with an increased risk for subsequent VTE (adjusted odds ratio, 0.32 [95% confidence interval, 0.02 to 1.66]; p = 0.274). Conclusions: Our findings suggest that, although patients with a history of VTE have an increased baseline risk for subsequent VTE, aspirin may be a suitable VTE prophylaxis in this group of patients. Level of Evidence: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
背景:近年来,阿司匹林已成为全关节置换术(TJA)后静脉血栓栓塞(VTE)预防的常用药物。然而,有静脉血栓栓塞病史的患者由于其基线风险增加,通常给予更积极的预防药物。本研究的目的是评估阿司匹林对有静脉血栓栓塞病史的患者是否有效。方法:这是一项单机构、回顾性队列研究。回顾了2008年至2020年间36333例TJA患者的电子临床记录。收集了人口学特征、合并症、术中因素和术后并发症的数据。进行倾向评分匹配分析,以及多变量回归分析,以解释混杂因素。结果:在36333例接受TJA的患者中,1087例(3.0%)患者有静脉血栓栓塞病史,且未接受慢性非阿司匹林治疗。有静脉血栓栓塞病史的患者发生静脉血栓栓塞的风险(1.4%)明显高于无静脉血栓栓塞病史的患者(0.9%)(p = 0.03)。然而,有静脉血栓栓塞病史的患者服用阿司匹林(0.4%)与服用其他静脉血栓栓塞预防药物的患者(1.5%)相比,静脉血栓栓塞的发生率并没有显著降低(p = 0.208)。倾向评分匹配显示两组间静脉血栓栓塞发生率无差异(2.2%比0.55%;P = 0.372)。在考虑静脉血栓栓塞风险的回归分析中,阿司匹林的使用与随后发生静脉血栓栓塞的风险增加无关(校正优势比为0.32[95%可信区间,0.02至1.66];P = 0.274)。结论:我们的研究结果表明,尽管有静脉血栓栓塞病史的患者随后发生静脉血栓栓塞的基线风险增加,但阿司匹林可能是这组患者预防静脉血栓栓塞的合适药物。证据等级:治疗性III级。有关证据水平的完整描述,请参见作者说明。
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引用次数: 2
Modified Scarf Osteotomy with Medial Capsular Interposition Combined with Metatarsal Shortening Offset Osteotomy 改良围巾截骨联合内侧囊间置联合跖骨缩短偏移截骨
Pub Date : 2022-05-24 DOI: 10.2106/JBJS.21.01486
Y. Etani, M. Hirao, K. Ebina, H. Tsuboi, T. Noguchi, G. Okamura, A. Miyama, K. Takami, A. Nampei, S. Tsuji, H. Owaki, S. Okada, J. Hashimoto
Background: Patients who have noninflammatory arthritis of the feet may develop destructive changes on the first metatarsal head and painful dislocation of the metatarsophalangeal (MTP) joint of 1 or more lesser toes. This aim of this study was to compare feet with noninflammatory arthritis and those with rheumatoid arthritis (RA) with respect to the clinical and radiographic outcomes after treatment of these destructive deformities with a modified Scarf osteotomy with medial capsular interposition into the newly formed first MTP joint, combined with metatarsal shortening offset osteotomy. Methods: A retrospective observational study of 93 feet (31 with noninflammatory arthritis and 62 with RA) was performed. Hallux and lesser-toe scores on the Japanese Society for Surgery of the Foot (JSSF) scoring system, a self-administered foot evaluation questionnaire (SAFE-Q), and preoperative and postoperative radiographic parameters were evaluated. Results: There were significant improvements at the time of the final follow-up in the mean scores on the hallux and lesser-toe scales of the JSSF system and in the SAFE-Q score. The postoperative JSSF lesser-toes function score was better for the feet with noninflammatory arthritis feet than the feet with RA. There was no significant difference in the hallux valgus angle (HVA) between 1 month postoperatively and the final follow-up for both groups. Furthermore, the HVA showed a strong correlation between the 1-month and final follow-up values. Conclusions: The combination of the modified Scarf osteotomy with medial capsular interposition and shortening metatarsal offset osteotomy was useful and safe in feet with noninflammatory arthritis. The HVA at 1 month after surgery is useful to predict the HVA within 5 years after surgery. The postoperative clinical score for the lesser toes was better in the feet with noninflammatory arthritis. Level of Evidence: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
背景:患有非炎症性足部关节炎的患者可能会在第一跖骨头发生破坏性变化,并在1个或多个小脚趾的跖趾趾关节(MTP)关节脱位疼痛。本研究的目的是比较非炎症性关节炎和类风湿关节炎(RA)患者在使用改良的围巾截骨术(内侧包膜插入新形成的第一MTP关节)结合跖骨缩短偏移截骨术治疗这些破坏性畸形后的临床和影像学结果。方法:对93例脚(31例非炎性关节炎,62例类风湿性关节炎)进行回顾性观察研究。根据日本足部外科学会(JSSF)评分系统、自我管理的足部评估问卷(SAFE-Q)以及术前和术后放射学参数评估拇趾和小脚趾评分。结果:在最后随访时,JSSF系统的拇趾和小脚趾量表的平均得分以及SAFE-Q得分均有显著改善。非炎症性关节炎足部术后JSSF小脚趾功能评分优于类风湿关节炎足部。两组患者术后1个月与最后随访时拇外翻角(HVA)无显著差异。此外,HVA在1个月和最终随访值之间显示出很强的相关性。结论:改良的围巾截骨联合内侧囊间置和缩短跖骨偏移截骨术对非炎性关节炎足部有效且安全。术后1个月的HVA对预测术后5年内的HVA有重要意义。非炎性关节炎足部术后小脚趾的临床评分较好。证据等级:治疗性IV级。完整的证据等级描述见作者指南。
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引用次数: 0
Lateral Ulnar Collateral Ligament of the Elbow Joint 肘关节尺侧副韧带
Pub Date : 2022-05-20 DOI: 10.2106/JBJS.21.01406
Atsuhiro Fukai, A. Nimura, M. Tsutsumi, Hitomi Fujishiro, K. Fujita, J. Imatani, K. Akita
Background: To improve the clinical results of lateral ulnar collateral ligament (LUCL) reconstruction of the elbow joint, better understanding of the anatomy of the aponeuroses and joint capsule could be relevant. This study considers the previously described anatomy of the LUCL in relation to the related aponeuroses and joint capsule rather than as a discrete ligament. We hypothesized that the deep aponeuroses of the superficial extensor muscles and supinator form a relevant portion of the joint capsule previously defined as the LUCL. Methods: Twenty-four elbows (12 right) from 21 embalmed cadavers (age at the time of death, 54 to 99 years) were included in the study. Twenty elbows were studied macroscopically and 4, histologically. The joint capsule was detached from the bones, and local thickness was quantitatively analyzed using micro-computed tomography (micro-CT). Results: The supinator aponeurosis and joint capsule intermingled to form a thick membrane (mean and standard deviation, 4.8 ± 1.2 mm), which we termed “the capsulo-aponeurotic membrane.” It was thicker than the anterior (1.3 ± 0.4 mm) and posterior (2.5 ± 0.9 mm) parts of the capsule of the humeroradial joint (p < 0.001). The capsulo-aponeurotic membrane had a wide attachment on the distal part of the extensor digitorum communis and extensor digiti minimi (EDC/EDM) origin of the humerus, the lateral part of the coronoid process, and the posterior part of the radial notch of the ulna. The humeral attachment had a fibrocartilaginous structure. The deep aponeuroses of the EDC and extensor carpi ulnaris (ECU) were connected to the capsulo-aponeurotic membrane. Conclusions: The capsulo-aponeurotic membrane was composed of the supinator aponeurosis and joint capsule and was attached to the lateral epicondyle of the humerus, radial side of the coronoid process, and posterior part of the radial notch on the ulna. The entire structure appeared identical to the commonly defined lateral collateral ligament. The most posterior part was connected to the EDC and ECU aponeuroses, which is commonly labeled the LUCL but does not exist as a discrete ligament. Clinical Relevance: Consideration of the accurate anatomy of the extensive attachment of the capsulo-aponeurotic membrane could provide useful clues for improvement in techniques of LUCL reconstruction and lateral epicondylitis pathology.
背景:为了提高肘关节外侧尺侧副韧带(LUCL)重建的临床效果,更好地了解腱膜和关节囊的解剖结构可能是相关的。本研究考虑了先前描述的LUCL与相关腱膜和关节囊的解剖关系,而不是作为离散韧带。我们假设浅表伸肌和旋后肌的深腱膜形成了关节囊的相关部分,之前定义为LUCL。方法:选取21具尸体(死亡年龄54 ~ 99岁)的24只肘部(右12只)作为研究对象。对20例肘部进行了宏观观察,4例进行了组织学观察。将关节囊与骨分离,用微计算机断层扫描(micro-CT)定量分析局部厚度。结果:旋后肌腱膜与关节囊混合形成一层厚膜(平均值和标准差为4.8±1.2 mm),我们称之为“囊膜-腱膜”。它比肱骨关节囊前部(1.3±0.4 mm)和后部(2.5±0.9 mm)厚(p < 0.001)。囊膜-腱膜广泛附着于肱骨趾共伸肌和指小伸肌(EDC/EDM)远端、冠突外侧和尺骨桡切迹后部。肱骨附着体为纤维软骨结构。EDC和尺腕伸肌(ECU)的深层腱膜连接到囊膜-腱膜。结论:髌腱膜由旋后肌腱膜和关节囊组成,附着于肱骨外侧上髁、冠突桡侧和尺骨桡侧切迹后部。整个结构与通常定义的外侧副韧带相同。最后方的部分连接到EDC和ECU腱膜,通常被标记为LUCL,但不存在离散韧带。临床意义:考虑囊膜-腱膜广泛附着的准确解剖,可以为LUCL重建技术和外侧上髁炎病理的改进提供有用的线索。
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引用次数: 7
期刊
The Journal of Bone and Joint Surgery
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