霸王大雅抗痘散粉的配方研究市区)。乙醇提取

Susi Novaryatiin, Nursheilla Rizky Amalia, S. Ardhany
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引用次数: 2

摘要

巴旺达亚克(Eleutherine bulbosa饰)Urb是鸢尾科的一种,原产于印度尼西亚加里曼丹中部。既往研究报道,球芽草乙醇提取物及其乳膏制剂具有抗菌作用,能抑制致痘细菌的生长,对皮肤无明显不良反应。本研究旨在以球芽草乙醇提取物为原料制备散粉,并测定其物理性能和抗菌活性。以不同浓度的球莲乙醇提取物F0(0%)、F1(5%)、F2(10%)、F3(15%)配制松粉配方。用圆盘扩散法评价散粉的感官、均匀性和抗菌活性。结果表明,球芽草乙醇提取物可制成疏松的粉末制剂。配方颜色偏黄(F0),棕灰(F1),浅棕色(F2和F3),具有典型的薄荷气味,质地光滑,均匀。所有配方均抑制痤疮丙酸杆菌、表皮葡萄球菌和金黄色葡萄球菌的生长。本研究表明,F3 (Formula 3)因其感官特性、均匀性和抑菌活性,具有抗痤疮散粉的潜力,其最大抑菌带直径为17.6±3.1 mm。
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Formulation of Anti Acne Loose Powder of Bawang Dayak (Eleutherine bulbosa (Mill.) Urb.) Ethanol Extract
Bawang dayak (Eleutherine bulbosa (Mill.) Urb is one of the notable Iridaceae family, originating from Central Kalimantan, Indonesia. Previous studies have reported that E. bulbosa ethanol extract and its cream preparation have antibacterial properties that can inhibit the growth of acne-causing bacteria and cause no significant skin adverse reaction. This study aimed to make a loose powder preparation from E. bulbosa ethanol extract and determine its physical evaluation and antibacterial activity. Loose powder formulation was made with various concentrations of E. bulbosa ethanol extract, F0 (0%), F1 (5%), F2 (10%), and F3 (15%). Loose powder evaluates for organoleptic, homogeneity, and antibacterial activity by the disc diffusion method. The results show that E. bulbosa ethanol extract can produce a loose powder formulation. The color of the formula is rather yellow (F0), brown-ash (F1), and light brown (F2 and F3), which has a typical mint odor, smooth texture, and homogeneous. All formulations inhibited the growth of Propionibacterium acnes, Staphylococcus epidermidis, and Staphylococcus aureus. This present study showed the potential of Formula 3 (F3) as an anti-acne loose powder due to its organoleptic properties, homogeneity, and antibacterial activity, which has the largest inhibition zone diameter of 17.6 ± 3.1 mm.
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