以先天性多发性息肉样口腔肿块为表现的上睑肌:一个令人惊讶的病例报告

H. Shukla, C. Agrawal, C. Sarat, D. Ram
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引用次数: 0

摘要

新生儿先天性膝外肌(CE)可以是一个惊人的悲惨景象,无论是父母和卫生保健专业人员参与新生儿护理。这些婴儿口腔肿瘤可能非常大,占据大部分口腔,造成气道阻塞或干扰进食的风险,伴有明显的面部畸形。1871年,Neumann首次描述了新生儿先天性膝外肌。它最常位于上颌前牙槽嵴,女性轻微偏爱。临床表现为带梗突起肿块。在病变较大的情况下,机械性口鼻阻塞会损害胎儿的吞咽和新生儿呼吸功能,导致产前羊水过多或产后呼吸功能障碍。组织学上,先天性瞳孔显示特征性的大细胞,胞浆呈颗粒状,梭形细胞类似成纤维细胞。确切的组织起源仍不确定,各种起源理论有上皮细胞、未分化间充质细胞、周细胞、成纤维细胞、平滑肌细胞和神经相关细胞。在此,我们报告了一名新生女婴在上颌骨和下颌骨发生多发性先天性膝挛缩,并进行了调查、治疗和随访。
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Epulis presenting as congenital multiple polypoidal oral mass lesion: A surprising case report
A newborn infant with congenital epulis (CE) can be a striking miserable sight for both parents and health care professionals involved in neonatal care. These tumours of the infant mouth can be remarkably large, occupying much of the oral cavity and posing a risk of airway obstruction or interfering with feeding with marked facial deformity. Neumann first described congenital epulis of newborn in 1871. It is most frequently located on the anterior maxillary alveolar ridge with slight female predilection. It clinically appears as a pedunculated protuberant mass. In cases with large lesions, mechanical oral and nasal obstruction can impair fetal deglutition and neonatal respiratory efforts resulting in polyhydramnios prenatally or respiratory impairment postnatally. Histologically Congenital epulis shows characteristic large cells with granular cytoplasm and spindle cells resembling fibroblasts. The exact histogenesis is still uncertain, various theories of origin are epithelial, undifferentiated mesenchymal cells, pericytes, fibroblast, smooth muscle cells and nerve related cells. Herein we report a newborn female child with Multiple Congenital epulis arising from maxilla and mandible with investigation, management and follow-up.
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