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Factors affecting uptake of natural family planning methods among clients at the reproductive health clinic of Ahmadu Bello University Teaching Hospital, Zaria, Nigeria 影响在尼日利亚扎里亚Ahmadu Bello大学教学医院生殖健康诊所接受自然计划生育方法的因素
Pub Date : 2019-07-01 DOI: 10.4103/archms.archms_14_19
H. Umar, N. Ameh, Umma Suleiman, F. Bakari
Background: The use of natural family planning (NFP) methods is low worldwide with few existing data. Aim: The aim of the study is to determine the factors affecting the use and discontinuation of NFP methods in our setting. Methodology: In this descriptive cross-sectional study, 302 clients who presented at the Reproductive Health Clinic of Ahmadu Bello University, Zaria, were interviewed, with the aid of pretested questionnaires. Sociodemographic variables, reasons affecting the use, and discontinuation of NFP methods were recorded and analyzed using SPSS software version 15. Results: Among the 302 clients interviewed, 88.1% (266) had used a form of family planning method: 38.4% (116) used NFP, 49.7% (150) used artificial methods, whereas 37.1% (43) discontinued the NFP methods. Major factors hindering the use of an NFP method include lack of awareness (24%), been single (17%), unknown reason (17%), irregular menstrual cycle (10%), and fear of method failure (8%). Major factors for discontinuing the NFP methods include high failure rates (21%), irregular menstrual cycle (18%), introduction to other methods (14%), want of conception (12%), and fear of pregnancy (12%). Conclusion: The most common factor affecting the uptake of NFP was lack of awareness. Failure rates and irregular menstrual cycles were the common denominators, affecting both the use and discontinuation of NFP methods.
背景:自然计划生育(NFP)方法在世界范围内的使用率很低,现有数据很少。目的:本研究的目的是确定在我们的环境中影响NFP方法使用和停止的因素。方法:在这项描述性横断面研究中,利用预试问卷对在扎里亚Ahmadu Bello大学生殖健康诊所就诊的302名患者进行了访谈。社会人口学变量、影响NFP方法使用的原因和停止使用使用SPSS软件版本15记录和分析。结果:在302名受访客户中,88.1%(266人)采用了某种形式的计划生育方法,其中38.4%(116人)采用了非计划生育方法,49.7%(150人)采用了人工方法,37.1%(43人)停止了非计划生育方法。阻碍使用NFP方法的主要因素包括缺乏意识(24%)、单身(17%)、原因不明(17%)、月经周期不规律(10%)和害怕方法失败(8%)。停止使用NFP方法的主要原因包括失败率高(21%)、月经周期不规律(18%)、采用其他方法(14%)、不想受孕(12%)和害怕怀孕(12%)。结论:影响NFP摄取的最常见因素是认知不足。失败率和月经周期不规律是共同的特征,影响着NFP方法的使用和停止。
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引用次数: 0
Pattern of visceral metastasis from breast cancer patients in Ahmadu Bello University Teaching Hospital, Zaria, North Western Nigeria 尼日利亚西北部扎里亚Ahmadu Bello大学教学医院乳腺癌患者内脏转移的模式
Pub Date : 2019-07-01 DOI: 10.4103/archms.archms_15_19
P. Abur, L. Yusufu, V. Odigie
Background: Visceral metastasis from breast cancer usually results in high tumor burden with poor prognosis. Aim: This study aimed to document the pattern, treatment, and outcome of breast cancer patients with visceral metastasis in our hospital. Patients and Methods: This is a 5-year prospective study of breast cancer patients with visceral metastasis from January 2011 to December 2015. All patients had tru-cut biopsy to establish diagnosis. Chest X-ray, abdominopelvic ultrasound, and computed tomography of the thoracoabdominal region were done to establish the extent of visceral organ involvement. Information documented included patients' biodata, histology, site of visceral metastasis, treatment, and outcome. Results: Two hundred and fourteen out of 1087 patients with breast cancer had visceral metastasis (19.7%). Their age ranged 15–83 years. Eighty-four (39.4%) patients had metastasis to the lungs. Thirty-nine (18.3%) patients had metastasis to the liver. Fifty-eight (27%) patients had metastasis to two or more visceral organs. One hundred and eighty-one (84.6%) patients had chemotherapy, 158 (73.8%) had hormonal therapy, whereas 103 (49.1%) had surgery. The mortality at 3-year follow-up was 58.4%. Conclusion: The lungs were the most common organ of visceral metastasis followed by the liver in this study. A significant percentage had metastasis to two or more visceral organs. Early presentation will reduce the incidence of visceral metastasis and the high mortality associated with it.
背景:乳腺癌内脏转移通常导致肿瘤负担高且预后差。目的:本研究旨在记录本院乳腺癌内脏转移患者的模式、治疗和预后。患者和方法:这是一项2011年1月至2015年12月的5年乳腺癌内脏转移患者的前瞻性研究。所有患者均行真切活检以确定诊断。胸部x光片、腹部盆腔超声和胸腹区计算机断层扫描确定脏器受累程度。记录的信息包括患者的生物资料、组织学、内脏转移部位、治疗和结果。结果:1087例乳腺癌患者中有214例发生内脏转移(19.7%)。他们的年龄在15-83岁之间。84例(39.4%)患者有肺转移。39例(18.3%)患者有肝转移。58例(27%)患者有两个或更多内脏器官转移。化疗181例(84.6%),激素治疗158例(73.8%),手术103例(49.1%)。3年随访死亡率为58.4%。结论:肺是本研究中最常见的内脏转移器官,其次是肝脏。有相当比例的患者转移到两个或更多内脏器官。早期出现将减少内脏转移的发生率和与之相关的高死亡率。
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引用次数: 1
Aortic arch aneurysm presenting as ortner's syndrome 主动脉弓动脉瘤表现为奥特纳综合征
Pub Date : 2019-07-01 DOI: 10.4103/archms.archms_17_18
P. Yakubu, N. Khanna, Emmanuel Edafe, S. Rao, A. Abubakar
Ortner's syndrome is defined as left recurrent laryngeal nerve palsy resulting from cardiovascular disease. Though it was first reported in patients with dilated left atrium in mitral stenosis, many cases have been associated with other cardiovascular diseases such as thoracic aortic aneurysm, enlarge pulmonary artery, abberent subclavian artery etc. We report a case of 45 year old presented with hoarseness and dyspnea who was confirmed to have aortic arch aneurysm. His symptoms resolved completely after transthoracic endovascular aortic repair (TEVAR)
奥特纳氏综合征定义为由心血管疾病引起的左喉返神经麻痹。虽然在二尖瓣狭窄的左心房扩张患者中首次报道,但许多病例与其他心血管疾病有关,如胸主动脉瘤、肺动脉扩张、锁骨下动脉脱落等。我们报告一个45岁的病例提出声音嘶哑和呼吸困难谁被证实有主动脉弓动脉瘤。经胸血管内主动脉修复术(TEVAR)后症状完全缓解。
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引用次数: 0
Effect of gestational age at booking on feto-maternal outcome at a Nigerian tertiary hospital 尼日利亚一家三级医院预约时胎龄对胎母结局的影响
Pub Date : 2019-07-01 DOI: 10.4103/archms.archms_37_18
J. Zaman, D. Isah, A. Isah
Background: Antenatal care (ANC) is one of the pillars of safe motherhood initiative aimed at preventing adverse pregnancy outcome. Early initiation of ANC may provide avenue for early identification and management of many medical illnesses in pregnancy with the resultant better feto-maternal outcome. The objective of the study was to determine the average gestational age (GA) at booking and to determine the effect of GA at booking on the feto-maternal outcome. Materials and Methods: This was a prospective cohort study of 414 women consecutively recruited at the booking clinic of the Teaching Hospital from September 2016 to July 2017. This was divided into two arms, early and late booking. However, only 186 and 189 women in the early and late booking women, respectively, completed the study and their data were available for analysis, and they were followed up to delivery. Results: The mean GA at booking in the study was 19.4 ± 8.14 weeks. The incidence rate of low-birth-weight was 8.3%. The recorded incidence rate of low-birth-weight of 7.8% among early attendees was similar to 8.8% recorded among those that booked late in pregnancy (P = 0.373). The overall stillbirth rate in this study was 29.33/1000 birth. The cumulative incidence of hypertensive disorders in pregnancy in the study was 12.8%. The overall mean packed cell volume (PCV) at booking was 33.6 ± 3.2 and similar to the respective PCV at booking in both early and the late booking women. The PCV at delivery was, however, significantly higher among those women that booked early when compared with those that booked late. Conclusion: The mean GA at booking in our unit is 19.4 ± 8.14. Early booking and access to routine hematinics may guarantee sustenance of this recorded higher PCV at delivery. Furthermore, educated and less parous women tend to book early from this study.
背景:产前保健(ANC)是安全孕产倡议的支柱之一,旨在预防不良妊娠结果。早期开展产前检查可为早期发现和管理妊娠期许多医学疾病提供途径,从而改善胎母结局。该研究的目的是确定预订时的平均胎龄(GA),并确定预订时的GA对胎母结局的影响。材料与方法:本研究是一项前瞻性队列研究,纳入了2016年9月至2017年7月在教学医院预约诊所连续招募的414名女性。这分为两臂,早订票和晚订票。然而,在早预约和晚预约的女性中,分别只有186名和189名女性完成了这项研究,她们的数据可供分析,并对她们进行了随访,直到分娩。结果:本研究的平均GA为19.4±8.14周。低出生体重儿发生率为8.3%。记录的低出生体重发生率在早参加者中为7.8%,与在怀孕后期参加者中记录的8.8%相似(P = 0.373)。本研究的死胎率为29.33/1000。妊娠期高血压疾病的累计发病率为12.8%。预约时的总体平均堆积细胞体积(PCV)为33.6±3.2,与早期和晚期预约时的PCV相似。然而,分娩时的PCV在提前预订的妇女中明显高于晚预订的妇女。结论:本院预约时平均GA为19.4±8.14。早期预约和常规血液学检查可以保证在分娩时维持这一较高的PCV记录。此外,受教育程度高、生育较少的女性更倾向于提前预订。
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引用次数: 2
Clinicopathological features, treatment, and outcome of pregnancy-associated breast cancer in Ahmadu Bello University Teaching Hospital, Zaria, Northwestern Nigeria 尼日利亚西北部扎里亚Ahmadu Bello大学教学医院妊娠相关乳腺癌的临床病理特征、治疗和结局
Pub Date : 2019-07-01 DOI: 10.4103/archms.archms_5_19
P. Abur, L. Yusufu, V. Odigie
Background: Pregnancy-associated breast cancer (PABC) is breast cancer diagnosed during pregnancy or within 1 year of delivery. It is the most frequent malignancy diagnosed during pregnancy or lactation. There is a paucity of information on PABC in our hospital. Aim: The aim of the study is to highlight the clinicopathological features, treatment, and outcome of PABC in the center. Materials and Methods: It was a 6-year prospective study of PABC from January 2007 to December 2012 at our hospital. Information documented included patient's biodata, clinical features, pathological types, receptor status, staging, treatment, and outcome of PABC patients. Results: A total of 1344 patients had breast cancer during the study period. 31 patients (2.3%) had PABC. Age ranged 20–43 years, median 31 years. Common clinical features were: breast lump/mass – 27 (87.1%) patients, skin thickness – 10 (32.3%), nipple retraction – 9 (29.0%), and inflammation – 6 (19.4%). 19 (61.3%) patients were diagnosed in pregnancy: first trimester – 4 (12.9%), second trimester – 7 (22.6%), third trimester – 8 (25.8%), while 12 (38.7%) were within 1 year of delivery. Twenty-two patients (71.0%) had advanced disease. Twenty-four (77.4%) patients had invasive ductal carcinoma. Thirteen (59.1%) patients were ER/PR positive, 6 (27.3%) were triple negative, and 3 (13.6%) were HER2 positive. Twenty-four patients (77.4%) had vaginal delivery. Three patients (9.7%) had spontaneous abortion and 1 patient (3.2%) had still birth. 25 babies (80.6%) were alive and well. 17 patients (54.8%) had modified radical mastectomy (2 patients in second trimester and 15 patients after delivery), 25 (80.6%) had chemotherapy, 14 (45.2%) had radiotherapy, and 1 (3.2%) received trastuzumab. Mortality was 8 (25.8%). Conclusion: PABC constituted 2.3% of all breast cancer patients in our hospital. Majority (71%) presented with advanced disease. 3 out of every 4 were invasive ductal carcinoma, while 1 in 4 were triple negative. The mortality was 25.8%.
背景:妊娠相关性乳腺癌(PABC)是指在怀孕期间或分娩后1年内诊断出的乳腺癌。它是妊娠或哺乳期最常见的恶性肿瘤。我们医院关于PABC的信息很少。目的:本研究的目的是强调中心PABC的临床病理特征,治疗和结果。材料与方法:2007年1月至2012年12月在我院进行为期6年的PABC前瞻性研究。记录的信息包括患者的生物资料、临床特征、病理类型、受体状态、分期、治疗和PABC患者的预后。结果:研究期间共有1344例患者患乳腺癌。31例(2.3%)有PABC。年龄20 ~ 43岁,中位31岁。常见的临床特征是:乳房肿块/肿块27例(87.1%),皮肤厚度10例(32.3%),乳头内缩9例(29.0%),炎症6例(19.4%)。19例(61.3%)患者被诊断为妊娠:妊娠早期4例(12.9%),妊娠中期7例(22.6%),妊娠晚期8例(25.8%),分娩1年内12例(38.7%)。22例(71.0%)为晚期疾病。浸润性导管癌24例(77.4%)。ER/PR阳性13例(59.1%),三阴性6例(27.3%),HER2阳性3例(13.6%)。经阴道分娩24例(77.4%)。自然流产3例(9.7%),死产1例(3.2%)。25例(80.6%)存活且健康。改良根治性乳房切除术17例(54.8%)(妊娠中期2例,分娩后15例),化疗25例(80.6%),放疗14例(45.2%),曲妥珠单抗1例(3.2%)。死亡率8例(25.8%)。结论:PABC占我院所有乳腺癌患者的2.3%。大多数(71%)表现为疾病晚期。3 / 4为浸润性导管癌,1 / 4为三阴性。死亡率为25.8%。
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引用次数: 0
Effectiveness of sweeping of membranes in reducing the incidence of elective induction of labor for postdate pregnancies 膜清扫术在降低晚期妊娠择期引产发生率中的有效性
Pub Date : 2019-01-01 DOI: 10.4103/archms.archms_36_18
M. Nyamzi, D. Isah, R. Offiong, A. Isah
Introduction: Prolonged pregnancy is a high-risk pregnancy that is associated with increased maternal morbidity and increased perinatal morbidity and mortality. Objectives: The objective was to evaluate the effectiveness of sweeping of the fetal membranes to reduce the incidence of elective induction of labor for postdate pregnancy and to compare pregnancy outcome among women who had sweeping of membranes at 40 weeks with those who did not have sweeping of membranes. Subjects and Methods: This was a randomized, controlled study conducted from September 2017 to June 2018. One hundred and ninety-four consenting participants with no contraindication to vaginal delivery were randomized into two groups, those who had membrane sweeping at 40–41 weeks' gestation and a control group who had vaginal examination to assess Bishop score only at recruitment. Participants were followed up to delivery. Results: Sweeping of membranes effectively reduced the incidence of elective induction of labor. The proportion of those that had spontaneous labor in the treatment group was 85 (87.6%) compared to the control group that had 67 (62.9%). This was statistically significant with P < 0.001. The incidence of induction of labor was significantly lower in the membrane sweeping group compared with the control group (12.4% vs. 37.1%; P < 0.001). There was a significant higher mean time interval from recruitment to admission (recruitment admission interval) among the control group (5.76 ± 2.75 days) compared with those that had membrane sweeping (3.35 ± 2.55; P < 0.001). Conclusion: Sweeping of the membranes appears an effective and safe procedure in reducing the incidence of elective induction of labor and duration of pregnancy at term in low-risk population.
妊娠延长是一种高危妊娠,与孕产妇发病率增加和围产期发病率和死亡率增加有关。目的:目的是评估胎膜清扫术在减少晚期妊娠择期引产发生率方面的有效性,并比较40周时进行胎膜清扫术与未进行胎膜清扫术的妊娠结局。对象和方法:这是一项随机对照研究,于2017年9月至2018年6月进行。194名同意无阴道分娩禁忌的参与者被随机分为两组,一组在妊娠40-41周进行膜清扫,另一组仅在招募时进行阴道检查以评估Bishop评分。参与者被跟踪到分娩。结果:扫膜术可有效降低择期引产的发生率。治疗组自然分娩85例(87.6%),对照组67例(62.9%)。P < 0.001,差异有统计学意义。扫膜组引产发生率明显低于对照组(12.4% vs 37.1%;P < 0.001)。对照组从招募到入院的平均时间间隔(招募入院间隔)(5.76±2.75天)明显高于扫膜组(3.35±2.55天;P < 0.001)。结论:在低危人群中,扫膜术在减少择期引产发生率和足月妊娠持续时间方面是一种有效和安全的方法。
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引用次数: 2
Necrotizing fasciitis of the breast in Ahmadu Bello University Teaching Hospital, Zaria, Northwestern Nigeria 尼日利亚西北部扎里亚Ahmadu Bello大学教学医院的乳房坏死性筋膜炎
Pub Date : 2019-01-01 DOI: 10.4103/archms.archms_4_19
P. Abur, L. Yusufu, V. Odigie
Context: Necrotizing fasciitis of the breast is rare globally. There is an observed increase in the number of cases seen in our hospital. Moreover, there is no previous documentation on the disease from this center. Aims: The aim was to highlight the clinical features, predisposing factors, complications, treatment, and outcome of necrotizing fasciitis of the breast. Settings and Design: It was a 5-year prospective study from January 2012 to December 2016. Subjects and Methods: The biodata, clinical features, predisposing factors, complications, treatment, and outcome of necrotizing fasciitis of the breast were documented. Statistical Analysis Used: The results were analyzed using SPSS software version 21 and presented as percentages and charts. Results: Thirty-nine out of 163 women with infective breast disease had necrotizing fasciitis of the breast. Majority of the patients (28 [71.8%]) were <31 years. Most of the patients had low educational status (33 [84.6%]). The most common clinical features were foul-smelling discharging ulcers/sinuses and necrosis of the skin of the breast in all patients. Majority of the patients (29 [74.4%]) were lactating mothers. Poorly treated mastitis/breast abscess was the predominant predisposing factor. Culture revealed polymicrobial organisms in 20 (51.3%) patients. Thirty-six (92.3%) patients had serial wound debridement, 25 (64.1%) had split-thickness skin grafting, and 3 (7.7%) had toileting mastectomy. Mortality rate was 10.3%. Conclusions: Necrotizing fasciitis of the breast is not uncommon in our center. Majority of the patients were illiterate with low socioeconomic status. Poorly treated mastitis/breast abscess in lactating women was the major predisposing factor.
背景:坏死性乳房筋膜炎在全球范围内是罕见的。我们医院的病例数量明显增加。此外,该中心以前没有关于该疾病的文献。目的:目的是强调乳房坏死性筋膜炎的临床特点,易感因素,并发症,治疗和结局。环境与设计:2012年1月至2016年12月,为期5年的前瞻性研究。研究对象和方法:记录乳房坏死性筋膜炎的生物资料、临床特征、易感因素、并发症、治疗和结局。统计分析使用:采用SPSS软件21版对结果进行分析,并以百分比和图表的形式呈现。结果:163例乳腺感染性疾病患者中有39例发生乳腺坏死性筋膜炎。大多数患者(28例[71.8%])年龄<31岁。多数患者文化程度较低(33例[84.6%])。所有患者最常见的临床特征是恶臭排出性溃疡/鼻窦和乳房皮肤坏死。29例(74.4%)为哺乳期母亲。治疗不良的乳腺炎/乳房脓肿是主要的诱发因素。20例(51.3%)患者培养发现多微生物。连续创面清创36例(92.3%),裂皮植皮25例(64.1%),排尿乳房切除术3例(7.7%)。死亡率为10.3%。结论:乳腺坏死性筋膜炎在本中心并不少见。患者多为文盲,社会经济地位低。哺乳期妇女治疗不良的乳腺炎/乳房脓肿是主要的诱发因素。
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引用次数: 0
Gastric outlet obstruction in adults in the University of Benin Teaching Hospital: A 5-year prospective study 贝宁大学教学医院成人胃出口梗阻:一项5年前瞻性研究
Pub Date : 2019-01-01 DOI: 10.4103/archms.archms_22_19
P. Agbonrofo, O. Irowa, V. Odigie
Background: Gastric outlet obstruction (GOO) is a contemporary surgical challenge. It is due to mechanical pyloroduodenal obstruction of gastric emptying. In Africa, cicatrizing duodenal ulcer or antral tumors are common causes; resultant inanition, fluid, electrolyte, and nutritional derangements could be life-threatening. Definitive therapy aims at relieving the obstruction. Aim: To highlight causes, clinical features, and outcome of management of GOO in the University of Benin Teaching Hospital. Patients and Methods: This was a 60-month prospective study from July 1, 2013, to June 30, 2018. Consecutive adult patients with GOO were studied. Diagnosis was confirmed using barium meal, esophago-gastro-duodenoscopy, biopsy, and operative findings. Preoperative optimization required nasogastric tube suctioning/warm saline lavage, intravenous fluids, antibiotics, and blood transfusion. Results: There were 52 GOO patients, constituting 7.9% of 659 gastrointestinal conditions requiring surgery during the study period. Operative intervention occurred in 50 (96.2%) patients. The male:female ratio was 1.7:1. The age ranges from 32 to 89 years, with a mean age of 63.5 ± 15.3 years. Most patients were in the 7th-8th decades of life (33 patients, 63.5%). Nonbilous vomiting and epigastric pain occurred in 50 (96.2%) patients, while 49 (94.2%) patients had weight loss. Mean duration of symptoms 10.5 ± 12.1 weeks. Malignant obstructions were 63.5% (33 patients). Palliative by-pass was effected in 58.0% (29 patients). Hospital stay was 16–23 days. Mortality rate was 3.8% (2 patients). Conclusions: GOO is a disease of the elderly in our region. Presentation is late. Most require surgical intervention. The most common cause is malignant obstruction. Most patients require prolonged, adequate preoperative resuscitation/optimization. We advocate early referral, routine endoscopy, and biopsy for patients with epigastric pain in the subregion.
背景:胃出口梗阻(GOO)是当代外科的一个挑战。这是由于机械性幽门十二指肠阻碍胃排空所致。在非洲,愈合性十二指肠溃疡或胃窦肿瘤是常见的原因;由此导致的营养不良、体液、电解质和营养紊乱可能危及生命。最终治疗的目的是解除梗阻。目的:探讨贝宁大学教学医院粘粘症的病因、临床特点及治疗效果。患者和方法:这是一项为期60个月的前瞻性研究,时间为2013年7月1日至2018年6月30日。对连续的成人粘粘症患者进行研究。诊断通过钡餐,食管-胃-十二指肠镜检查,活检和手术检查证实。术前优化需要鼻胃管抽吸/温盐水灌洗、静脉输液、抗生素和输血。结果:研究期间有52例粘粘症患者,占659例需要手术的胃肠道疾病的7.9%。手术干预50例(96.2%)。男女比例为1.7:1。年龄32 ~ 89岁,平均63.5±15.3岁。大多数患者年龄在7 -8岁(33例,63.5%)。50例(96.2%)患者出现非胆汁性呕吐和胃脘痛,49例(94.2%)患者出现体重减轻。平均症状持续时间10.5±12.1周。恶性梗阻33例,占63.5%。29例(58.0%)患者行姑息性旁路治疗。住院时间16-23天。死亡率为3.8%(2例)。结论:粘胶瘤是本地区老年人常见病。演讲迟到了。大多数需要手术干预。最常见的原因是恶性梗阻。大多数患者需要延长,充分的术前复苏/优化。我们提倡早期转诊,常规内镜检查和活检患者的胃脘痛在亚区域。
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引用次数: 0
An audit of breast lumps detected during cancer screening: A report from Southwest Nigeria 在癌症筛查中发现的乳房肿块审计:来自尼日利亚西南部的一份报告
Pub Date : 2019-01-01 DOI: 10.4103/archms.archms_2_19
B. Ayoade, H. Ebili, Olubunmi Fatungase, Collins Nwokoro, B. Salami, A. Adekoya, A. Oyelekan, B. Adefuye, A. Olatunji
Background: In low-Human Development Index countries, population-based screening programs for breast cancer are virtually nonexistent, but there are occasional screening programs organized by nongovernmental organizations in these countries. This study aims to describe the clinical and histopathological characteristics and the prevalence of breast diseases detected by clinical breast examination (CBE) in a cohort of women who participated in a community-based breast screening program. Methodology: This is a retrospective cross-sectional study of women who were referred for assessment in our Breast Clinic following CBE during a breast cancer screening program. Palpable lesions were subjected to biopsy and histopathological examinations. Results: Of the 2450 women screened, 102 had breast biopsy. Twenty-one were malignant (20.6%) and 79 were benign (77.5%). The mean age for benign breast disease was 32 ± 14 years, whereas that for women with malignant breast lesions was 57 ± 11 years (P < 0.001). Sixty-three women (61.8%) were married, 59 (57.8%) had tertiary education, and 27 (26.5%) were petty traders. The mean lump size was 3.8 ± 3.9 cm for benign lumps and 6.2 ± 4.2 cm for malignant lumps (P = 0.014). Histopathological examination revealed that 20.6% of the lumps were malignant, 50% were benign neoplasm (fibroadenoma,) 17.6% were fibrocystic change and related conditions (fibroadenosis), 5.9% were sclerosing lesions, 2% were inflammatory lesions, 2% were benign proliferative breast disease, and 2% were inadequate sample. Two of the 12 breast lumps (16.6%) were detected for the first time at screening, of which two were malignant. This constitutes 1.9% (2/102) of all the lumps biopsied and 0.081% of all the women who had CBE. Conclusion: This study has demonstrated that CBE as a tool for early detection of breast cancer should be encouraged and applied. It confirms that fibroadenoma is the most common cause of clinically obvious breast lumps.
背景:在人类发展指数较低的国家,几乎不存在以人群为基础的乳腺癌筛查项目,但这些国家偶尔会有非政府组织组织的筛查项目。本研究的目的是描述临床乳房检查(CBE)发现的乳房疾病的临床和组织病理学特征和流行率在一组参加社区乳房筛查计划的妇女中。方法:这是一项回顾性横断面研究,研究对象是在乳腺癌筛查项目中,在CBE后转介到我们乳腺诊所接受评估的妇女。可触及的病变进行活检和组织病理学检查。结果:在2450名接受筛查的女性中,102名进行了乳腺活检。恶性21例(20.6%),良性79例(77.5%)。乳腺良性病变的平均年龄为32±14岁,乳腺恶性病变的平均年龄为57±11岁(P < 0.001)。63名妇女(61.8%)已婚,59名(57.8%)受过高等教育,27名(26.5%)是小商贩。良性肿块的平均大小为3.8±3.9 cm,恶性肿块的平均大小为6.2±4.2 cm (P = 0.014)。组织病理学检查显示,20.6%的肿块为恶性,50%为良性肿瘤(纤维腺瘤),17.6%为纤维囊性改变及相关疾病(纤维腺病),5.9%为硬化性病变,2%为炎症性病变,2%为乳腺良性增生性疾病,2%为样本不足。12个乳房肿块中有2个(16.6%)在筛查时首次发现,其中2个为恶性。这占所有活检肿块的1.9%(2/102),占所有CBE女性的0.081%。结论:CBE作为一种早期发现乳腺癌的工具,值得推广和应用。证实纤维腺瘤是临床上最常见的乳房肿块。
{"title":"An audit of breast lumps detected during cancer screening: A report from Southwest Nigeria","authors":"B. Ayoade, H. Ebili, Olubunmi Fatungase, Collins Nwokoro, B. Salami, A. Adekoya, A. Oyelekan, B. Adefuye, A. Olatunji","doi":"10.4103/archms.archms_2_19","DOIUrl":"https://doi.org/10.4103/archms.archms_2_19","url":null,"abstract":"Background: In low-Human Development Index countries, population-based screening programs for breast cancer are virtually nonexistent, but there are occasional screening programs organized by nongovernmental organizations in these countries. This study aims to describe the clinical and histopathological characteristics and the prevalence of breast diseases detected by clinical breast examination (CBE) in a cohort of women who participated in a community-based breast screening program. Methodology: This is a retrospective cross-sectional study of women who were referred for assessment in our Breast Clinic following CBE during a breast cancer screening program. Palpable lesions were subjected to biopsy and histopathological examinations. Results: Of the 2450 women screened, 102 had breast biopsy. Twenty-one were malignant (20.6%) and 79 were benign (77.5%). The mean age for benign breast disease was 32 ± 14 years, whereas that for women with malignant breast lesions was 57 ± 11 years (P < 0.001). Sixty-three women (61.8%) were married, 59 (57.8%) had tertiary education, and 27 (26.5%) were petty traders. The mean lump size was 3.8 ± 3.9 cm for benign lumps and 6.2 ± 4.2 cm for malignant lumps (P = 0.014). Histopathological examination revealed that 20.6% of the lumps were malignant, 50% were benign neoplasm (fibroadenoma,) 17.6% were fibrocystic change and related conditions (fibroadenosis), 5.9% were sclerosing lesions, 2% were inflammatory lesions, 2% were benign proliferative breast disease, and 2% were inadequate sample. Two of the 12 breast lumps (16.6%) were detected for the first time at screening, of which two were malignant. This constitutes 1.9% (2/102) of all the lumps biopsied and 0.081% of all the women who had CBE. Conclusion: This study has demonstrated that CBE as a tool for early detection of breast cancer should be encouraged and applied. It confirms that fibroadenoma is the most common cause of clinically obvious breast lumps.","PeriodicalId":93819,"journal":{"name":"The Archives of comparative medicine and surgery","volume":"2010 1","pages":"1 - 6"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73345280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pattern of referral before and after referral intervention among primary health centers in North-Western Nigeria 尼日利亚西北部初级保健中心转诊干预前后的转诊模式
Pub Date : 2019-01-01 DOI: 10.4103/archms.archms_9_19
S. Asuke, K. Sabitu, M. Ibrahim
Introduction: The revised Nigerian National Health Policy and the WHO Expert Committee on the Role of Hospitals as the First Referral Level both recognize primary health care (PHC) as the entry point in the referral system. This study was carried out to assess the effect of training of PHC workers on referral and instituting referral focal person among PHCs on key referral indicators in Zaria and Giwa local government areas, North-Western Nigeria. Methodology: The study was a quasi-experimental study with pre- and postinterventional components carried out among seventy participants in the intervention and 62 participants in the control groups who were selected through a multistaged sampling technique. Data were collected using a structured self-administered questionnaire containing close-ended questions. Data were analyzed with SPSS software version 20.0. Results: Preintervention, majority of the respondents (74.3%) in the intervention and (67.7%) control groups had not received training on referral process. Postintervention, increase was noted in mean referral rate from 0.18 ± 0.28 to 0.52 ± 0.34, which was statistically significant, and mean counter referral rate from 0 ± 0 to 40.34 ± 45.53 in the study group, but there was no statistically significant change in the control group. Conclusion: Postintervention, significant increases were noticed in two of the practice indicators; referral rate and counter-referral rate in the study group only. The other practice indicators did not record a significant increase.
导言:经修订的尼日利亚国家卫生政策和世卫组织关于医院作为第一转诊级别作用的专家委员会都承认初级卫生保健(PHC)是转诊系统的切入点。在尼日利亚西北部的Zaria和Giwa地方政府地区,开展了这项研究,以评估初级保健工作人员转诊培训和在初级保健中心设立转诊协调人对关键转诊指标的影响。方法:该研究是一项准实验研究,包括干预前和干预后的组成部分,在70名干预组参与者和62名通过多阶段抽样技术选择的对照组参与者中进行。数据收集使用结构化的自我管理问卷,其中包含封闭式问题。数据采用SPSS 20.0软件进行分析。结果:干预前,干预组(74.3%)和对照组(67.7%)的受访者未接受过转诊流程培训。干预后,研究组平均转诊率由0.18±0.28上升至0.52±0.34,差异有统计学意义;研究组平均反转诊率由0±0上升至40.34±45.53,对照组无统计学意义变化。结论:干预后,两项实践指标均有显著提高;仅在研究组中的转诊率和反转诊率。其他实践指标没有显著增加。
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引用次数: 2
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The Archives of comparative medicine and surgery
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