南榜H. Abdul Moeloek综合医院收治的糖尿病足溃疡患者细菌特征与死亡率之间的关系

Iswandi Darwis, Gusti Ngurah P Pradnya Wisnu, S. Mentari
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摘要

大约25%的糖尿病患者在其生活中经历过糖尿病足溃疡,并伴有各种细菌感染。据报道,由革兰氏阴性菌和革兰氏阳性菌引起的感染具有不同的炎症模式,后者据报道具有较高的死亡率。本研究是一项分析性观察性研究,采用横断面设计来确定糖尿病足溃疡中细菌特征与死亡率之间的关系。数据来自2017-2020年楠榜H. Abdul Moeloek综合医院收治的糖尿病溃疡患者的医疗记录。共发现131例糖尿病足溃疡患者,年龄中位数为53岁,男性占43.5%,女性占56.5%。平均血红蛋白9.3 g/dl,白细胞19.0 ×103/ml,血小板422.1 ×103/ml。平均住院时间为10.7天。住院期间死亡18例,其中革兰氏阴性单菌组死亡15例。单微生物感染致死率和细菌特征的Fischer精确检验结果(p=0.688)表明,糖尿病足溃疡的感染性病原体特征与致死率之间没有关系。关键词:细菌,糖尿病,糖尿病足溃疡,死亡率对应:iswandi.darwis@gmail.com
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The relationship between bacterial characteristics and mortality in diabetic foot ulcers' patients admitted to Dr. H. Abdul Moeloek General Hospital, Lampung
ABSTRACT Around 25% of people with diabetes experience diabetic foot ulcers in their lives, accompanied by infections due to various types of bacteria. Infection due to Gram-negative and Gram-positive bacteria are reported to have different inflammation patterns, where the latter being reported to have a higher mortality rate. This study was an analytic observational study with a cross-sectional design to determine the relationship between bacterial characteristics and mortality in diabetic foot ulcers. Data were obtained from medical records of diabetic ulcer patients admitted to Dr. H. Abdul Moeloek General Hospital, Lampung, in 2017–2020. There were 131 diabetic foot ulcers patients identified, with the median age of the subjects was 53 years, 43.5% of the subject were male, and 56.5% were female. The mean hemoglobin was 9.3 g/dl, WBCs were 19.0 ×103/ml, and platelets were 422.1 ×103/ml. The mean length of stay in the hospital was 10.7 days. Eighteen subjects died during the hospital stay, with 15 of them were from the Gram-negative monomicrobial group. The results of the Fischer Exact test on mortality and bacterial characteristics among monomicrobial infections (p=0.688) indicate no relationship between the characteristics of the infectious pathogen and mortality in diabetic foot ulcers. Keywords: bacteria, diabetes, diabetic foot ulcers, mortalityCorrespondence: iswandi.darwis@gmail.com
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