S. Thomas, Zhuliet Grami, Sharvil Mehta, Kushal Patel
{"title":"5-氟尿嘧啶的不良反应:关注罕见的副作用","authors":"S. Thomas, Zhuliet Grami, Sharvil Mehta, Kushal Patel","doi":"10.14800/CCM.1266","DOIUrl":null,"url":null,"abstract":"5-fluorouracial (5-FU) is an antimetabolite chemotherapy drug. 5-FU has many adverse effects like any other chemotherapy agent as it has effects not only on cancer cells, but healthy cell as well. Serious side effects which are uncommon (occurring in about 1% of patients) and will be the focus of this paper are cardiac effects, hyperammonemia or encephalopathy and neurologic effects. There are many other side effects associated with 5-FU. In this paper we will discuss the rare side effects and alternatives on what to do if they occur during treatment based on case reports.","PeriodicalId":9576,"journal":{"name":"Cancer cell & microenvironment","volume":"2 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2016-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"21","resultStr":"{\"title\":\"Adverse effects of 5-fluorouracil: Focus on rare side effects\",\"authors\":\"S. Thomas, Zhuliet Grami, Sharvil Mehta, Kushal Patel\",\"doi\":\"10.14800/CCM.1266\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"5-fluorouracial (5-FU) is an antimetabolite chemotherapy drug. 5-FU has many adverse effects like any other chemotherapy agent as it has effects not only on cancer cells, but healthy cell as well. Serious side effects which are uncommon (occurring in about 1% of patients) and will be the focus of this paper are cardiac effects, hyperammonemia or encephalopathy and neurologic effects. There are many other side effects associated with 5-FU. In this paper we will discuss the rare side effects and alternatives on what to do if they occur during treatment based on case reports.\",\"PeriodicalId\":9576,\"journal\":{\"name\":\"Cancer cell & microenvironment\",\"volume\":\"2 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-04-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"21\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cancer cell & microenvironment\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.14800/CCM.1266\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cancer cell & microenvironment","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14800/CCM.1266","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Adverse effects of 5-fluorouracil: Focus on rare side effects
5-fluorouracial (5-FU) is an antimetabolite chemotherapy drug. 5-FU has many adverse effects like any other chemotherapy agent as it has effects not only on cancer cells, but healthy cell as well. Serious side effects which are uncommon (occurring in about 1% of patients) and will be the focus of this paper are cardiac effects, hyperammonemia or encephalopathy and neurologic effects. There are many other side effects associated with 5-FU. In this paper we will discuss the rare side effects and alternatives on what to do if they occur during treatment based on case reports.
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