伊朗Qazvin省非黑色素瘤皮肤癌流行病学研究

Akram Beheshtiroy, F. Hajmanoochehri
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引用次数: 3

摘要

统计检验包括t检验和卡方检验。结果:484例患者中,男性294例(60.7%),女性190例(39.3%)。以基底细胞居多(77.7%),其余为鳞状细胞。最常见的受累部位是头部和头皮。最常见的易感因素是露天工作(70.7%),既往有治疗头癣的放射史(26.1%),以及慢性皮肤病如烧伤痂、慢性病变、瘘管和光化性角化病(35.7%)。最常见的Fitzpatrick皮肤表型为II或III型(75.4%)。NMSC的发病率与水烟和口服避孕药(OCP)的使用有显著的相关性。结论:皮肤表型II和III是本研究中发现的最常见的类型,这可能是由于这些表型在研究人群中频率较高。除颈部和头皮以外的其他区域NMSC发病率较低可能与研究人群使用的遮盖方式的重要性有关。在本研究中也观察到了NMSC发生的已知危险因素。在相当比例的患者中观察到放疗治疗头癣的历史,这可能导致几十年后的癌症发病率。需要进一步的研究来确定水烟吸烟和使用OCP在NMSC发生中的作用。
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Epidemiological Study of Non-Melanoma Skin Cancers Qazvin Province, Iran
and statistical tests including t-test and chi-square tests. Results: Of the 484 patients, 294 (60.7%) were male and 190 (39.3%) were female. Most cases of carcinoma were found in basal cells (77.7%) and the rest of squamous cells. The most common sites of involvement were the head and scalp. The most frequent predisposing factors were working in the open air (70.7%), history of previous radiation for treatment of tenia capitis (26.1%), and chronic skin diseases such as burn eschar, chronic lesion, fistula and actinic keratosis (35.7%). The most prevalent Fitzpatrick skin phenotypes were II or III (75.4%). There were significant correlations between the incidence of NMSC and hookah smoking and oral contraceptive pill (OCP) consumption. Conclusions: Skin phenotypes II and III were the most common types found in the present study and this could be due to the higher frequency of these phenotypes among the study population. The lower incidence of NMSC in areas other than the neck and scalp could be associated with the importance of covering style used by the population under study. Known risk factors for the incidence of NMSC were also observed in the present study. A history of radiotherapy for treatment of tenia capitis was observed in a considerable percentage of patients, which could lead to the incidence of cancer several decades later. Further studies are needed to determine the role of hookah smoking and the use of OCP in the occurrence of NMSC.
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