{"title":"伴有外阴疾病的育龄妇女异常子宫出血的预后","authors":"R. Blagoveshchensky, I. Tuchkina","doi":"10.15587/2519-4798.2023.275503","DOIUrl":null,"url":null,"abstract":"The purpose of the study was to elaborate on a prognostic model for predicting the development of abnormal uterine bleeding in women of reproductive age with accompanying extragenital disorders based on mathematical methods. \nMaterials and methods. The study, which was in 2019-2022, involved 100 women of reproductive age with AUB and accompanying extragenital disorders under observation, who made up the main group. The control group comprised 50 women of reproductive age undergoing medical checkups. On the basis of 23 diagnostic indicators, the most informative ones were mathematically selected for the prognosis of AUB in women with extragenital abnormalities. \nResults and their discussion. The prognosis of the risk of developing AUB in women of reproductive age with extragenital disorders was carried out on a double scale (0 – low probability, 1 – high probability). The search for diagnostically informative factors involved a set of 23 working indicators that were investigated in the examined patients using four levels of the risk scale. In order to solve this issue, the factors that have the greatest importance in the formation of the prognosis were selected using discriminant analysis methods, and a corresponding mathematical model was created. The classification functions made it possible to enter the practical plane and form rules for assessing the presence/absence of the risk of developing AUB in patients of reproductive age with extragenital disorders. The corresponding expressions are the following equations: \nNP = BAS ART*75.57+FSH*2.96+prolac*0.02+estrad*0.02-40.78 \nPP = BAS ART*105.35+FSH*0.79+prolac*0.1+estrad*0.08-114.49, \nwhere NP is a negative prognosis, PP is a positive prognosis. \nIf NP > PP, then the most likely prognosis is the absence of AUB in the patient; otherwise, if PP > NP – there is an increased risk of AUB. \nConclusion. Pulsation index in the basal arteries of the uterus, FSH, prolactin and estrogens are prognostically significant indicators for predicting the risk of abnormal uterine bleeding in patients of reproductive age with extragenital disorders. The above formula, obtained from the conducted discriminant analysis, makes it possible to predict bleeding in a specific patient","PeriodicalId":21672,"journal":{"name":"ScienceRise: Medical Science","volume":"26 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Prognosis of abnormal uterine bleeding in women of reproductive age with extragenital disorders\",\"authors\":\"R. Blagoveshchensky, I. Tuchkina\",\"doi\":\"10.15587/2519-4798.2023.275503\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The purpose of the study was to elaborate on a prognostic model for predicting the development of abnormal uterine bleeding in women of reproductive age with accompanying extragenital disorders based on mathematical methods. \\nMaterials and methods. The study, which was in 2019-2022, involved 100 women of reproductive age with AUB and accompanying extragenital disorders under observation, who made up the main group. The control group comprised 50 women of reproductive age undergoing medical checkups. On the basis of 23 diagnostic indicators, the most informative ones were mathematically selected for the prognosis of AUB in women with extragenital abnormalities. \\nResults and their discussion. The prognosis of the risk of developing AUB in women of reproductive age with extragenital disorders was carried out on a double scale (0 – low probability, 1 – high probability). The search for diagnostically informative factors involved a set of 23 working indicators that were investigated in the examined patients using four levels of the risk scale. In order to solve this issue, the factors that have the greatest importance in the formation of the prognosis were selected using discriminant analysis methods, and a corresponding mathematical model was created. The classification functions made it possible to enter the practical plane and form rules for assessing the presence/absence of the risk of developing AUB in patients of reproductive age with extragenital disorders. The corresponding expressions are the following equations: \\nNP = BAS ART*75.57+FSH*2.96+prolac*0.02+estrad*0.02-40.78 \\nPP = BAS ART*105.35+FSH*0.79+prolac*0.1+estrad*0.08-114.49, \\nwhere NP is a negative prognosis, PP is a positive prognosis. \\nIf NP > PP, then the most likely prognosis is the absence of AUB in the patient; otherwise, if PP > NP – there is an increased risk of AUB. \\nConclusion. Pulsation index in the basal arteries of the uterus, FSH, prolactin and estrogens are prognostically significant indicators for predicting the risk of abnormal uterine bleeding in patients of reproductive age with extragenital disorders. The above formula, obtained from the conducted discriminant analysis, makes it possible to predict bleeding in a specific patient\",\"PeriodicalId\":21672,\"journal\":{\"name\":\"ScienceRise: Medical Science\",\"volume\":\"26 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ScienceRise: Medical Science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15587/2519-4798.2023.275503\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ScienceRise: Medical Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15587/2519-4798.2023.275503","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
本研究的目的是建立一种基于数学方法的预测育龄妇女异常子宫出血伴外阴疾病发展的预后模型。材料和方法。该研究于2019年至2022年进行,涉及100名育龄妇女,她们患有AUB并伴有外阴疾病,她们构成了主要群体。对照组由50名接受体检的育龄妇女组成。在23项诊断指标的基础上,以数学方式选择最具信息量的指标,用于诊断伴有外阴异常的女性AUB的预后。结果和讨论。对伴有外阴疾病的育龄妇女发生AUB风险的预后进行双评分(0 -低概率,1 -高概率)。对诊断信息因素的搜索涉及一组23个工作指标,在检查的患者中使用四个级别的风险量表进行调查。为了解决这一问题,采用判别分析方法选取在预后形成过程中最重要的因素,并建立相应的数学模型。分类功能可以进入实用层面,形成评估育龄伴外阴疾病患者是否存在AUB风险的规则。对应的表达式为:NP = BAS ART*75.57+FSH*2.96+prolac*0.02+estrad*0.02-40.78 PP = BAS ART*105.35+FSH*0.79+prolac*0.1+estrad*0.08-114.49,其中NP为阴性预后,PP为阳性预后。如果NP > PP,那么最可能的预后是患者无AUB;反之,如果PP > NP -则AUB的风险增加。结论。子宫基底动脉搏动指数、卵泡刺激素、催乳素、雌激素是预测育龄伴外阴疾病患者子宫异常出血风险的重要预后指标。上述公式是通过判别分析得出的,可以预测特定患者的出血情况
Prognosis of abnormal uterine bleeding in women of reproductive age with extragenital disorders
The purpose of the study was to elaborate on a prognostic model for predicting the development of abnormal uterine bleeding in women of reproductive age with accompanying extragenital disorders based on mathematical methods.
Materials and methods. The study, which was in 2019-2022, involved 100 women of reproductive age with AUB and accompanying extragenital disorders under observation, who made up the main group. The control group comprised 50 women of reproductive age undergoing medical checkups. On the basis of 23 diagnostic indicators, the most informative ones were mathematically selected for the prognosis of AUB in women with extragenital abnormalities.
Results and their discussion. The prognosis of the risk of developing AUB in women of reproductive age with extragenital disorders was carried out on a double scale (0 – low probability, 1 – high probability). The search for diagnostically informative factors involved a set of 23 working indicators that were investigated in the examined patients using four levels of the risk scale. In order to solve this issue, the factors that have the greatest importance in the formation of the prognosis were selected using discriminant analysis methods, and a corresponding mathematical model was created. The classification functions made it possible to enter the practical plane and form rules for assessing the presence/absence of the risk of developing AUB in patients of reproductive age with extragenital disorders. The corresponding expressions are the following equations:
NP = BAS ART*75.57+FSH*2.96+prolac*0.02+estrad*0.02-40.78
PP = BAS ART*105.35+FSH*0.79+prolac*0.1+estrad*0.08-114.49,
where NP is a negative prognosis, PP is a positive prognosis.
If NP > PP, then the most likely prognosis is the absence of AUB in the patient; otherwise, if PP > NP – there is an increased risk of AUB.
Conclusion. Pulsation index in the basal arteries of the uterus, FSH, prolactin and estrogens are prognostically significant indicators for predicting the risk of abnormal uterine bleeding in patients of reproductive age with extragenital disorders. The above formula, obtained from the conducted discriminant analysis, makes it possible to predict bleeding in a specific patient