大戟属四环三萜

G. Krstić, M. Novaković, M. Jadranin, V. Tešević
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引用次数: 2

摘要

本研究从乳草Euphorbia nicaeensis All中分离得到3个四环三萜:(3S,24S)-tirucall-7-ene-3,24,25-三醇(1)、(3S,24R)-tirucall-7-ene-3,24,25-三醇(2)和干扰素C(3)。采用干柱闪蒸硅胶色谱法和半制备正相高效液相色谱法。通过一维和二维核磁共振谱和文献综述确定了它们的结构。虽然这三种化合物以前曾从其他植物中分离到,但这是首次从尼卡伊螨中分离到。
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Tetracyclic triterpenoids from Euphorbia nicaeensis All
In this study, three tetracyclic triterpenes: (3S,24S)-tirucall-7-ene-3,24,25-triol (1), (3S,24R)-tirucall-7-ene-3,24,25-triol (2) and inoterpene C (3), were isolated from the milkweed Euphorbia nicaeensis All. using dry-column flash silica gel chromatography and semipreparative normal-phase HPLC. Their structures were determined on the basis of 1D and 2D NMR spectra and literature review. Although these three compounds have previously been isolated from other plant species, this is the first time that they have been isolated from E. nicaeensis.
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