弥散性浅浅光化性角化孔症、鲍文氏病和基底细胞癌。巧合还是罕见的双恶性变?

Todor Yordanov, E. Popchristova, Neli Koleva, I. Yungareva, J. Dimitrova, S. Márina
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引用次数: 0

摘要

弥散性浅浅光化性角化孔症(DSAP)是一种由多个环形角化过度病变组成的皮肤病。它们通常分布在双侧,主要影响四肢。DSAPs比Mibelli角化症分布更广,通常出现在40 - 50岁之间。鳞状细胞癌、Bowen病和基底细胞癌起源于Mibelli的经典型多孔角化症,文献记载甚多,但在DSAP中发生Bowen病和基底细胞癌的病例报道不多。我们报告一位77岁的女性,在组织学证实的DSAP中发展为双Bowen病和基底细胞癌。
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Disseminated superficial actinic porokeratosis, Bowen's disease and basal cell carcinoma. Coincidence or rare double malignant transformation?
Disseminated superficial actinic porokeratosis (DSAP) is a skin condition that consist of multiple annular, hyperkeratotic lesions. They are usually distributed bilaterally and mostly affect the extremities. DSAPs have a wider distribution than the porokeratosis of Mibelli and usually appears between the age of 40 and 50. Squamous cell carcinoma, Bowen’s disease, and basal cell carcinoma that arises in the classical type of porokeratosis of Mibelli is well-documented, but there are not many reported cases of Bowen’s disease and basal cell carcinoma arising in DSAP. We present a 77-year-old woman in whom the two– Bowen’s disease and Basal cell carcinoma develop in a histologically proven DSAP.
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