耐药:癌症药物开发的重要标准

Radhika Chelamalla
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引用次数: 1

摘要

分子靶向药物通过综合癌症患者的发病率和死亡率来解决治疗问题。然而,对优选有效的抗癌化合物仍有迫切的热情,最先进的临床前滥用药物评估在很大程度上忽视了对需求的回答。新的临床前策略,包括所有额外的小鼠模型和联合临床设计设计的审查,用于提高基于动物的转化研究的预测价格标签。在这里,我们看到了一个新的光出生的银汤匙临床前抗肿瘤药物的社会,其相关的局限性,和武断的方法来感受一个骨头的临床结果。
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Drug resistance: important criteria for cancer drug development
Molecularly targeted agents light at end of tunnel to resolve therapeutics by drawing together morbidity and mortality in patients by the whole of cancer. However, still an urgent has a passion for preferably effective anticancer compounds, state-of-the-art preclinical abused substance evaluations largely overlook to answer a need the demand. New preclinical strategies, including the review of with all the extras mouse models and co-clinical design designs, are for used to boost the predictive price tag of animal-based translational aries research. Here, we saw in a new light the society of born with a silver spoon preclinical antineoplastic agents, their associated limitations, and arbitrary methods to feel in one bones clinical outcomes.
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