评价甲状腺切除术后意外行甲状旁腺切除术的患者:一项回顾性队列研究

T. Allahverdi, Harun Bayram, Kenan Binnetoğlu, T. Anuk, U. Bulut
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摘要

目的:研究甲状腺手术中不慎行甲状旁腺切除术的患者术后甲状旁腺激素水平和低钙血症的发生率。材料和方法:我们回顾性评估了2011年1月至2017年3月期间接受甲状腺切除术的142例患者。对甲状腺切除术患者的人口学特征和病理诊断进行评价。确定病理标本中切除甲状旁腺的数目及位置。术后检查甲状旁腺激素水平。第2天测定钙含量。对低甲状旁腺激素和低钙患者给予补钙治疗。通过参考生化值来确定钙替代水平。出院后,在门诊检查钙和甲状旁腺激素水平,以确定低钙是短暂的还是永久性的。结果:142例患者中,男性23例(16.2%),女性119例(83.8%)。平均年龄49.5岁。其中双侧甲状腺全切除术131例,双侧甲状腺次全切除术3例,左全右甲状腺次全切除术3例,右全左甲状腺次全切除术2例,左甲状腺小叶切除术2例,辅助甲状腺切除术1例。2例患者行单侧颈部清扫(II、III、IV、V级),82例患者行中央淋巴结清扫。35例患者术中发现甲状旁腺组织被切除,其中女性33例(94.2%),男性2例(5.8%)。31例甲状旁腺组织偶然切除,4例非偶然切除。我们发现42例患者出现短暂性低钙血症,2例患者出现永久性低钙血症。讨论:我们发现一些甲状旁腺已被无意中切除,尽管仔细的甲状腺手术。我们认为术后检查甲状旁腺激素水平对确定低钙血症很重要。结论:
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Evaluation of patients who have undergone unintentional parathyroidectomy following thyroidectomy: a retrospective cohort study -
Aim: We investigated the postoperative parathormone levels and the incidence of hypocalcemia in patients who had inadvertently underwent parathyroidectomy during thyroid surgery . Material and Methods: We retrospectively evaluated a total of 142 patients who had undergone thyroidectomy between January 2011 and March 2017 from their charts. The demographic feature sand pathology diagnoses of the thyroidectomy patients were evaluated. The number of excised parathyroid glands in the pathology specimens and their location were determined. The PTH level was checked after surgery. Calcium was measured on the 2nd day. Calcium replacement was provided for patients with low PTH and calcium. The level of calcium replacement was determined by referring to biochemical values. Following discharge, the calcium and PTH levels were checked during outpatient visits to determine whether the hypocalcemia was transient or permanent. Results: The 142 patients consisted of 23 males (16.2%) and 119 females (83.8%). The mean age was 49.5 years. The surgery performed was bilateral total thyroidectomy in 131, bilateral subtotal thyroidectomy in 3, left total right subtotal thyroidectomy in 3, right total leftsubtotalthyroidectomy in 2, left thyroid lobectomy in 2, and complementary thyroidectomy in 1. Unilateral neck dissection (level II, III, IV, V) was performed in 2 patients and central lymphnode dissection in 82 patients. Parathyroid tissue was found to have been excised during surgery in 35 patients, consisting of 33 females (94.2%) and 2 males (5.8%). The parathyroid tissue had been removed incidentally in 31 and not incidentally in 4. We found transient hypocalcemia in 42 patients and permanent hypocalcemia in 2 patients. Discussion: We found that some parathyroid glands had been inadvertently removed despite careful thyroid surgery. We believe that checking the PTH level postoperatively is important in determining hypocalcemia. Conclusion:
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