接受皮肤点刺试验的特应性皮炎患者的特点

W. Nugroho, Evy Ervianti, I. Zulkarnain, A. Hidayati, D. Damayanti, B. Utomo, C. Prakoeswa
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摘要

背景:皮肤点刺试验(SPT)适用于I型超敏反应(快速型),其中包括特应性皮炎(AD)。然而,对于测试过敏原的SPT结果并不总是伴随着AD患者已知过敏原的历史。目的:探讨行SPT的AD患者的特点。方法:这是一项描述性回顾性研究,旨在确定2017年1月至2019年12月在印度尼西亚泗水Soetomo综合学术医院皮肤病和性病门诊过敏免疫科治疗的AD患者的人口统计学、过敏史、SPT结果以及阳性和阴性临床相关性。结果:共纳入284例AD患者。成人年龄组(20-59岁)在每年的AD患者就诊中占主导地位,2017年、2018年和2019年分别为58例(60.42%)、47例(46.08%)和65例(75.58%)。只有60例AD患者接受了SPT,其中大多数患者对粉尘过敏,30例(50.0%)。屋尘螨(HDM)过敏原SPT阳性比例最高,有41例(63.3%)。猫毛过敏原的临床相关性最大,所有患者(100.0%)的SPT结果均具有临床相关性。结论:本研究显示AD患者多为成年年龄组,且有粉尘过敏史。其中HDM过敏原SPT阳性比例最高,猫毛过敏原SPT阳性比例最高。
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Characteristics of Atopic Dermatitis Patients who Underwent Skin Prick Test
Background: Skin prick test (SPT) is indicated in type I hypersensitivity reactions (rapid type), among which is Atopic Dermatitis (AD). However, the results of SPT for the tested allergens are not always accompanied by history of known allergens in AD patients. Purpose: To identify the characteristics of AD patients who underwent SPT. Methods: This was a descriptive retrospective study to determine the demographics, allergy history, SPT results, and positive and negative clinical relevance in AD patients treated at Allergy Immunology Division of Dermatology and Venerology Outpatient Clinic Dr. Soetomo General Academic Hospital Surabaya-Indonesia from January 2017 to December 2019. Results: A total of 284 AD patients were included. The adult age group (20-59 years) predominated the AD patient’s visit every year with 58 patients (60.42%), 47 patients (46.08%), and 65 patients (75.58%) in 2017, 2018, and 2019, respectively. Only 60 AD patients underwent SPT, where most patients were allergic to dust with 30 patients (50.0%). House dust mite (HDM) allergen had the highest percentage of positive SPT result with 41 patients (63.3%). The greatest clinical relevance was found in cat fur allergen, where all patients (100.0%) had clinical relevance to their SPT result. Conclusion: This study shows that most AD patients were in adult age group and had a history of dust allergy. The highest percentage of positive SPT result was found in HDM allergen and the greatest clinical relevance was found in cat fur allergen.
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