L. D. Borges, H. H. Dias, E. Ferreira, Paulyenny Machado Alves, Beatriz Oliveira Silva, Kíllya de Paiva Santos, G. D. da Costa, T. R. Moreira, Daniel Souza Santos, R. M. Cotta
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引用次数: 1
摘要
背景:糖尿病(DM)目前被认为是一种全球性流行病，在未来几年中，各大洲都有令人担忧的预测，慢性肾脏疾病(CKD)是未及时诊断的主要后果之一。目的:本研究的目的是通过系统回顾和荟萃分析来估计慢性肾病患者中糖尿病的患病率。方法:对Pubmed (Medlaine)、Lilacs、Scopus、Scielo等主要免费数据库进行系统评价。两位研究者选择文章，提取数据并评估质量。使用随机效应模型对收集的数据进行评估。结果:在994篇文章中，17篇研究涉及三个大洲。CKD患者中DM的群体患病率(95% CI)为29%(23-35%)，异质性I2 = 99,86%， p = 0.00，不能用meta回归和亚组解释。结论:本研究证实了慢性肾病患者中糖尿病的高患病率，特别是在终末期肾病患者中，这表明需要早期诊断和及时治疗糖尿病，并考虑到这些疾病在世界范围内的社会和经济影响，在这一领域进行新的研究。
Prevalence of Diabetes Mellitus among individuals with chronic kidney disease: systematic review and meta-analysis
BACKGROUND: Diabetes Mellitus (DM) is currently considered a global epidemic, with alarming estimates for the coming years on all continents, with Chronic Kidney Disease (CKD) as one of its main consequences when a timely diagnosis is not made. OBJECTIVE: The objective of this study is to estimate the prevalence of DM among individuals diagnosed with CKD by means of a systematic review and meta-analysis. METHODS: A systematic review was carried out in the main free-access databases such as Pubmed (Medlaine), Lilacs, Scopus and Scielo. Two researchers selected the articles, extracted the data and evaluated the quality. The collected data were evaluated using a random effects model. RESULTS: Of 994 articles, 17 studies were included that looked at three continents. The group prevalence of DM among individuals with CKD (95% CI) was 29% (23-35%), with heterogeneity I2 = 99,86% and p = 0.00, which was not explained by meta-regression and subgroups. CONCLUSIONS: The present study confirmed the high prevalence of DM among individuals with CKD, especially among those with end-stage renal disease, demonstrating the need for early diagnosis and timely treatment of DM and new studies in this area, considering the social and economic impact of these diseases worldwide.
期刊介绍：
The International Journal of Evidence-Based Healthcare is the official journal of the Joanna Briggs Institute. It is a fully refereed journal that publishes manuscripts relating to evidence-based medicine and evidence-based practice. It publishes papers containing reliable evidence to assist health professionals in their evaluation and decision-making, and to inform health professionals, students and researchers of outcomes, debates and developments in evidence-based medicine and healthcare.
The journal provides a unique home for publication of systematic reviews (quantitative, qualitative, mixed methods, economic, scoping and prevalence) and implementation projects including the synthesis, transfer and utilisation of evidence in clinical practice. Original scholarly work relating to the synthesis (translation science), transfer (distribution) and utilization (implementation science and evaluation) of evidence to inform multidisciplinary healthcare practice is considered for publication. The journal also publishes original scholarly commentary pieces relating to the generation and synthesis of evidence for practice and quality improvement, the use and evaluation of evidence in practice, and the process of conducting systematic reviews (methodology) which covers quantitative, qualitative, mixed methods, economic, scoping and prevalence methods. In addition, the journal’s content includes implementation projects including the transfer and utilisation of evidence in clinical practice as well as providing a forum for the debate of issues surrounding evidence-based healthcare.
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