超声辅助锁骨上臂丛阻滞中添加地塞米松8mg至0.5%左布比卡因20ml的镇痛效果比较

Chetali Das, R. Mathur, Srishti Kukreja
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摘要

背景:超声辅助锁骨上阻滞是一种有效而实用的方法,可以在排列紧密的臂丛中使用小剂量的局麻药。本研究旨在评估Inj的镇痛和麻醉作用。地塞米松(8mg)辅助0.5%左布比卡因确定上肢手术成人臂丛阻滞患者首次抢救镇痛时间和24小时内所需抢救镇痛药物数量。结果:本前瞻性随机双盲介入研究在20 ~ 55岁的ASAI和II型患者中进行。A组(n=30)注射。左布比卡因20ml及注射。给予生理盐水2ml。B组(n=30)注射。左布比卡因20ml及注射。给予地塞米松2ml。第一次抢救镇痛所需时间A组为431.50±46.15 min, B组为749.38±62.41 min, p值< 0.001。结论:我们的研究推断,随着地塞米松的加入,救援镇痛的时间延长,救援镇痛的需求次数减少,感觉和运动阻滞的发生速度加快,持续时间延长。
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Clinical comparison of analgesic efficacy of addition of injection dexamethasone 8mg to 20ml 0.5% levobupivacaine in ultrasonography assisted supraclavicular brachial plexus block
Background: Ultrasonography-assisted supraclavicular block is an efficacious and practical method and allows us to use a lower volume of local anesthetic in compactly arranged brachial plexus. The study envisioned evaluating the analgesic and anesthetic effects of Inj. dexamethasone (8mg) as an adjuvant to 0.5% levobupivacaine to determine the time for first rescue analgesia and number of rescue analgesics needed in 24 hours duration in brachial plexus blockade in adult patients listed for upper limb surgeries. Results: This prospective randomized double-blind interventional study was carried out in ASAI and II, aged 20 to 55 years. In group A (n=30) Inj. Levobupivacaine 20ml and Inj. Normal saline 2ml was given. In group B (n=30) Inj. Levobupivacaine 20ml and Inj. Dexamethasone 2ml was given. The time for the demand of the first rescue analgesia was 431.50 ± 46.15 minutes in group A and 749.38 ± 62.41 minutes in group B, with a p-value < 0.001. The demand for rescue analgesics was more in Group A in contrast to Group B. Conclusion: We deduce with our study, with the addition of dexamethasone, the time for rescue analgesia is prolonged, and the number of rescue analgesic demands is reduced, with a faster onset and extended duration of both sensory and motor block.
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