{"title":"无创图像引导靶向药物递送镭纳米粒子在同步辐射下治疗人牙龈癌细胞、组织和肿瘤","authors":"A. Heidari, K. Schmitt, M. Henderson, E. Besana","doi":"10.15761/DOMR.1000348","DOIUrl":null,"url":null,"abstract":"In the current study, thermoplasmonic characteristics of Radium nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Radium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Radium nanoparticles by solving heat equation. The obtained results show that Radium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method. of with","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"5 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"10","resultStr":"{\"title\":\"Non-invasive image-guided targeted drug delivery of radium nanoparticles in human gum cancer cells, tissues and tumors treatment under synchrotron radiation\",\"authors\":\"A. Heidari, K. Schmitt, M. Henderson, E. Besana\",\"doi\":\"10.15761/DOMR.1000348\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In the current study, thermoplasmonic characteristics of Radium nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Radium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Radium nanoparticles by solving heat equation. The obtained results show that Radium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method. of with\",\"PeriodicalId\":10996,\"journal\":{\"name\":\"Dental, Oral and Maxillofacial Research\",\"volume\":\"5 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"10\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Dental, Oral and Maxillofacial Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15761/DOMR.1000348\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dental, Oral and Maxillofacial Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15761/DOMR.1000348","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Non-invasive image-guided targeted drug delivery of radium nanoparticles in human gum cancer cells, tissues and tumors treatment under synchrotron radiation
In the current study, thermoplasmonic characteristics of Radium nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Radium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Radium nanoparticles by solving heat equation. The obtained results show that Radium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method. of with