药用植物抗炎作用:分子药理学方法综述

D. Shil, Kishor Kumar Roy, Rasamalla Mounika, M. Reja, S. Saha, Ranjan Kumar Maji
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引用次数: 0

摘要

炎症是创造药物干预新方法的重要治疗靶点,也是许多疾病(如动脉粥样硬化和类风湿性关节炎)病理生理学的一个阶段。因此,对炎症的分子理解为药物创造带来了新的机会,并对当前的临床医学产生了重大的新影响。它还揭示了治疗作用的生物学靶点和机制,为改变复杂的生物系统开辟了新的机会。同时,使用药用植物来控制炎症已被推荐作为传统治疗方法的替代方案,用于各种情况,特别是当炎症被预期抑制时。在当代研究中,一些药用植物物种已被证明具有很强的抗炎特性。本文综述了姜黄素和茶树没食子儿茶素-3-没食子酸酯的化学成分和生物学特性,并对活性成分的抗炎分子药理学进行了综述。
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Medicinal plants use as an anti-inflammatory agent: a brief review on molecular pharmacological approach
Inflammation is a vital therapeutic target for creating new methods for pharmacological interventions, aside from being a stage in the pathophysiology of many diseases, such as atherosclerosis and rheumatoid arthritis. Thus, molecular understanding of inflammation has led to new opportunities for drug creation and significant new implications for current clinical medicine. It has also revealed the biological targets and mechanisms of therapeutic action, opening up new opportunities to alter complex biological systems. Meanwhile, using medicinal plants to control inflammation has been recommended as an alternative to traditional therapeutic approaches for a variety of conditions, particularly when suppression of inflammation is anticipated. Several medicinal plant species have been demonstrated to have strong anti-inflammatory properties in contemporary research. The review article was discussed about the chemical constituents and biological properties of therapeutically active plants including curcumin from Curcuma longa and epigallocatechin-3-gallate from Camellia sinensis, including the molecular pharmacology of active constituents against inflammation.
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