纳米颗粒作为一种新型给药系统的研究进展

M. Anees, M. I. Masood, M. Ilyas, Muhammad Ammad
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引用次数: 5

摘要

摘要:近年来,纳米技术对给药系统产生了重大影响。该技术在重塑新型给药系统(NDDS)的未来中发挥着独特的作用。纳米颗粒(NPs)是在临床医学和研究领域有着广泛应用的新型纳米材料之一。以纳米颗粒的形式包封治疗药物,与传统的治疗药物剂型相比,具有提高药物疗效、安全性、生物降解性、生物利用度和治疗指数等优势。本文主要综述了纳米管、固体脂质纳米颗粒、超顺磁性纳米颗粒、脂质体、量子点、树状大分子、陶瓷纳米颗粒和纳米红体等纳米颗粒给药系统及其在不同领域的应用。
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NANOPARTICLES AS A NOVEL DRUG DELIVERY SYSTEM A REVIEW
ABSTRACT:  Nanotechnology is showing a significant impact on the drug-delivery system over a past few years. This technology is playing a distinct role in remodeling the future of novel drug delivery system (NDDS). Nanoparticles (NPs) are one of the NDDS which exhibit vast applications in the field of clinical medicine and research. The encapsulation of therapeutic drugs in the form of nanoparticles shows advantageous effects, such as increasing drug efficacy, safety, bio-degradability, bioavailability and therapeutic index, over conventional dosage forms of these therapeutic drugs. The current review article mainly focuses on different types of nanoparticulate drug delivery systems including nanotubes, solid lipid nanoparticles, superparamagnetic nanoparticles, liposomes, quantum dots, dendrimers, ceramic nanoparticles and nanoerythrosomes as well as their applications in different field.
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