探讨孕妇乳酸脱氢酶水平、白细胞计数、低出生体重和子痫前期严重程度之间的关系:一项横断面研究(2021年7月至2022年6月)

IF 0.2 Q4 PHARMACOLOGY & PHARMACY Asian Journal of Pharmaceutical Research and Health Care Pub Date : 2023-08-13 DOI:10.55561/ajhr.v2i2.112
B. Talita, Nandia Primarintan, Talita Nandia Primarintan
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引用次数: 0

摘要

前言:本研究探讨孕妇乳酸脱氢酶(LDH)水平、白细胞计数、低出生体重和子痫前期严重程度之间的关系。2021年7月至2022年6月在玛琅的赛弗·安瓦尔医院进行。材料和方法:本研究采用横断面设计的描述性和分析性观察方法。对符合特定标准的孕妇进行LDH水平、白细胞计数、子痫前期严重程度和新生儿体重的评估。统计分析包括Kruskal-Wallis检验和Spearman相关来探讨变量之间的关系和显著性。结果:LDH水平和低出生体重在轻度子痫前期、重度子痫前期和子痫患者中存在显著差异。LDH水平与子痫前期的严重程度有关,而低出生体重与子痫相关。然而,白细胞水平在这两组之间没有显着差异。结论:本研究强调了早期评估和监测孕妇这些因素的必要性,旨在提高母婴结局。建议进一步研究以在不同人群中验证这些发现,并探索与子痫前期相关疾病相关的其他危险因素。总之,本研究阐明了LDH水平、白细胞计数、低出生体重和子痫前期严重程度之间的相互作用。结果强调了它们作为评估和管理子痫前期相关并发症的潜在标记物的重要性。
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Exploring The Relationship Between Lactate Dehydrogenase Levels, Leukocyte Counts, Low Birth Weight, and The Severity of Preeclampsia in Pregnant Women: A Cross-Sectional Study at Saiful Anwar Hospital Malang (July 2021 to June 2022)
Introduction: This study investigates the connection between lactate dehydrogenase (LDH) levels, leukocyte counts, low birth weight, and the severity of preeclampsia among pregnant women. Conducted at Saiful Anwar Hospital in Malang from July 2021 to June 2022. Material and Methods: This research utilizes a descriptive and analytical observational approach with a cross-sectional design. Pregnant women meeting specific criteria were evaluated for LDH levels, leukocyte counts, preeclampsia severity, and newborn birth weights. Statistical analyses, including the Kruskal-Wallis test and Spearman correlation, were employed to explore relationships and significance among variables. Results: There is significant differences in LDH levels and low birth weight across patients with mild preeclampsia, severe preeclampsia, and eclampsia. LDH levels were linked to preeclampsia severity, while low birth weight correlated with eclampsia. Leukocyte levels, however, did not exhibit notable differences among these group. Conclusion: This study underscores the necessity of early assessment and monitoring of these factors in pregnant women, aiming to enhance maternal and fetal outcomes. Further research is recommended to validate these findings in diverse populations and explore additional risk factors associated with preeclampsia-related conditions. In conclusion, this research illuminates the interplay between LDH levels, leukocyte counts, low birth weight, and preeclampsia severity. The outcomes emphasize their importance as potential markers for evaluating and managing preeclampsia-related complications.
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