自杀和非自杀自残

P. Soloff, C. Schmahl
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引用次数: 0

摘要

本章回顾了pd患者自杀行为和非自杀性自伤(NSSI)患病率的最新数据;尝试者与完成者的特征;边缘型人格障碍(BPD)自伤的流行病学研究。此外,本文还提出了自杀和自伤的解释模型。此外,还对自杀和自伤的神经生物学机制进行了全面的讨论,重点是情绪失调、冲动性、执行认知缺陷、情感干扰和认知功能以及内源性阿片系统的结构和功能神经影像学。本章最后详细描述了疼痛处理与自伤的相互作用。
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Suicide and Nonsuicidal Self-Injury
This chapter reviews current data on the prevalence of suicidal behavior and non-suicidal self-injury (NSSI) in patients with PDs; the characteristics of attempters versus completers; and the epidemiology of NSSI in borderline personality disorder (BPD). In addition, it presents explanatory models for suicide and NSSI. Also, there are comprehensive discussions of the neurobiological mechanisms involved in both suicidality and NSSI focusing on the structural and functional neuroimaging of emotion dysregulation, impulsivity, executive cognitive deficits, affective interference and cognitive function, and the Endogenous Opioid System. The chapter concludes with a detailed description of pain processing as it interacts with NSSI.
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