传统阿育吠陀配方在COVID-19治疗中的应用

Mayur S. Mahajan, K. Bobe, B. Chavan
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摘要

冠状病毒病2019 (COVID-19)是一种由严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)引起的新型传染病,属于冠状病毒科。首例病例于2019年12月报告,该疾病已成为大流行。免疫调节功能受损是其发病机制和导致COVID-19患者预后不良的因素之一。已有许多研究将候选药物用作抗病毒药物或免疫调节剂。然而,这些研究结果表明,候选药物对这种疾病没有显著的效果。同时,人们认为食用草药免疫调节剂可以预防甚至治愈COVID-19。不幸的是,尚未进行专门的临床前和临床试验来评估草药免疫调节剂的作用。根据以往实验的一般概念,某些天然化合物可能对治疗COVID-19有效。本文综述了从姜黄、金鸡纳、Ashwagandh和莲花清文等植物中提取的治疗新型冠状病毒病的中药。此外,我们还讨论了在COVID-19大流行期间使用草药的利弊,得出了一些结论,并在会议结束时提出了建议。
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Traditional Ayurvedic Formulation in the Management of COVID-19
Coronavirus disease 2019 (COVID-19) is a new infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that belongs to the coronavirus family. The first case was reported in December 2019, and the disease has become a pandemic. Impaired immune regulation is one of the factors that play a role in its pathogenesis and results in poor outcomes of COVID-19 patients. There have been many studies with drug candidates used as antivirals or immunomodulators. However, the results of these investigations showed that the drug candidates were not significantly effective against the disease. Meanwhile, people believe that consuming herbal immunomodulators can prevent or even cure COVID-19. Unfortunately, specific preclinical and clinical trials to evaluate the effects of herbal immunoregulators have not been conducted. Certain natural compounds might be effective for the treatment of COVID-19 based on general concepts from previous experiments. This review discusses some herbal agents extracted from various plants, including Curcuma longa, Cinchona, Ashwagandh aand Lianhuaqingwen, which are considered for the treatment of COVID-19. In addition, we discuss the pros and cons of utilising herbal medicine during the COVID-19 pandemic, draw some conclusions, and make recommendations at the end of the session.
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