无创和微创技术预防/治疗老年人牙根龋的疗效——文献综述

Nisha Sundaragopal , Lisa Hou , Reyes Enciso
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引用次数: 0

摘要

目的总结无创和微创牙根龋预防措施在老年人牙根龋治疗中的效果。方法截止到2021年2月18日在PubMed进行电子检索。本综述只纳入了用英语发表的随机对照试验(RCTs),这些试验测量了老年人牙根龋的结局。如果评估局部氟化物清漆/凝胶、氯己定(CHX)、非创伤性修复治疗(ART)或氟化二胺银(SDF)预防和/或阻止老年人牙根龋的疗效,研究是合格的。结果本综述共纳入16项rct。在四项研究中,使用旋转器械的常规治疗与使用手动器械的ART治疗在修复体存活率上没有显著差异。1% CHX清漆(每3个月一次)、5%氟化钠(NaF)清漆(每3个月一次)和38% SDF溶液在OHI的基础上每年应用比单独使用OHI在3年内更有效地预防新的牙根龋(3种干预措施之间没有差异)。每天使用0.2%中性NaF漱口水可降低长期设施中老年人的龋齿发生率,效果优于0.12% CHX。1.2%酸化磷酸氟(APF)凝胶组的新病变数量显著低于安慰剂冲洗组(P <0.05),而氟化漱口水组出现更多的逆转牙根病变。在老年人中,每年应用38%的SDF溶液并每6个月进行一次口腔健康教育(OHE)可有效阻止和预防牙根龋。与单独使用氟化物清漆相比,Cervitec™(1% chx /1%百里香酚清漆)和氟化物清漆的组合在一组虚弱的老年人中成功地阻止了现有的牙根龋。结论与对照组相比,使用0.2%中性NaF漱口水、1% CHX清漆、Cervitec™、APF凝胶、每年应用SDF并结合口腔健康教育等多种微创干预措施对老年人牙根性龋病的遏制和预防效果均有显著改善。然而,由于针对每种干预措施的研究很少,需要进一步的研究来证实这些结果。
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Efficacy of non-invasive and minimally invasive techniques for the prevention/management of root caries in older adults - A literature review

Purpose

To summarize the effectiveness of non-invasive and minimally invasive root caries preventive interventions in older adults.

Methods

An electronic search was conducted in PubMed up to February 18, 2021. Only randomized controlled trials (RCTs) published in English language with root caries outcomes measured on older adults were included in this review. Studies were eligible if assessing the efficacy of either topical fluoride varnish/gel, chlorhexidine (CHX), atraumatic restorative treatment (ART), or silver diamine fluoride (SDF) to prevent and/or arrest root caries in older adults.

Results

A total of 16 RCTs were included in this review. No significant differences were found between conventional therapy with rotary instruments and ART with hand instruments in survival rates of restorations in four studies. 1% CHX varnish (every 3 months), 5% sodium fluoride (NaF) varnish (every 3 months) and 38% SDF solution applied annually in addition to OHI were more effective preventing new root caries than OHI alone over a period of 3 years (with no differences between the 3 interventions). A 0.2% neutral NaF mouth rinse used daily reduced the incidence of caries among elders in long-term facilities and performed better than 0.12% CHX. The number of new lesions in the 1.2% acidulated phosphate fluoride (APF) gel group was significantly lower than in the placebo rinse group (P < 0.05), however the fluoridated mouth rinse group had more reversed root lesions. 38% SDF solution applied annually in combination with oral health education (OHE) every 6 months was efficacious in arresting and preventing root caries among older adults. The combination of Cervitec™ (1%CHX/1% thymol varnish) and fluoride varnish was successful in arresting exisiting root caries in a group of frail older adults compareed to fluoride varnish alone.

Conclusions

Multiple minimally invasive interventions showed significant improvements in arresting and preventing root carious lesions in older adults compared to control groups, including the use of 0.2% neutral NaF mouth rinse, 1% CHX varnish, Cervitec™, APF gel and annual application of SDF combined with oral health education. However, further studies are needed to confirm these results as few studies could be found for each intervention.

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