Dentistry Review最新文献

{"title":"Artificial intelligence–driven smartphone imaging for early detection of oral cancer: How far have we come? A comprehensive literature review","authors":"Helga Alm ,&nbsp;Tuula Salo ,&nbsp;Amr Elseragy","doi":"10.1016/j.dentre.2026.100162","DOIUrl":"10.1016/j.dentre.2026.100162","url":null,"abstract":"<div><h3>Objective</h3><div>This review aimed to evaluate the evidence from previous studies on smartphone-based imaging and artificial intelligence (AI)–assisted mobile health (mHealth) technologies for the early detection of oral potentially malignant disorders (OPMDs) and oral cancer, focusing on their diagnostic performance and feasibility in low-resource settings.</div></div><div><h3>Methods</h3><div>A structured literature review was conducted, including 23 peer-reviewed articles published between 2015 and 2024. Eligible studies investigated smartphone-based imaging, tele-dentistry platforms, dual-modality autofluorescence systems, mobile cytology tools, mHealth community programs, and AI-driven models. Data extraction was based on study design, sample size, assessment tool, reference standard, and diagnostic outcomes.</div></div><div><h3>Results</h3><div>The 23 studies demonstrated that smartphone-based imaging and mHealth platforms are not only feasible but also effective for OPMDs and oral cancer screening in both community and clinical settings. These platforms reported sensitivity ranged from 70% to 99%, specificity from 64% to 100%, and accuracy from 81% to 97%, depending on the device used, the screening context, and operator expertise. Moreover, AI-driven models such as DenseNet, HRNet, MobileNet, and CNN-based ensembles achieved diagnostic accuracies of 84–95%, in some cases even approaching specialist-level performance. Similarly, dual-modality autofluorescence and white-light imaging systems enhanced classification accuracy, reaching 79–87%. Importantly, community-based mHealth programs involving frontline health workers showed high diagnostic agreement with specialists (κ up to 0.92), thereby enabling large-scale, cost-effective screening. Moreover, MeMoSA® applications demonstrated strong concordance with conventional oral examination (sensitivity 92–94%, specificity up to 95.5%), thus supporting their integration into structured referral pathways.</div></div>","PeriodicalId":100364,"journal":{"name":"Dentistry Review","volume":"6 1","pages":"Article 100162"},"PeriodicalIF":0.0,"publicationDate":"2026-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146102622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stability outcomes of internal and external distractors in maxillary distraction osteogenesis for cleft lip and palate: A systematic review","authors":"Divya Raja ,&nbsp;Navaneethan Ramasamy ,&nbsp;Yashoda Ashok ,&nbsp;Neha Rani","doi":"10.1016/j.dentre.2025.100161","DOIUrl":"10.1016/j.dentre.2025.100161","url":null,"abstract":"<div><h3>Background</h3><div>Cleft lip and palate (CLP) often result in maxillary hypoplasia due to surgical scarring and impaired growth. In such cases, distraction osteogenesis (DO) is a well-established technique for achieving maxillary advancement. Both internal and external distractors are widely applied, yet their relative long-term skeletal stability is not known.</div></div><div><h3>Objective</h3><div>To systematically evaluate the long-term skeletal stability of Le Fort I osteotomy with distraction osteogenesis using internal and external distraction devices in managing maxillary deficiency among CLP patients.</div></div><div><h3>Materials and Methods</h3><div>Following PRISMA guidelines and with prior PROSPERO registration (CRD420251026923), a comprehensive search of PubMed, Scopus, and Web of Science databases was conducted up to April 6, 2025. Studies involving CLP patients who underwent maxillary distraction osteogenesis with either internal or external devices were included. Data extraction and quality assessment were performed using the Newcastle-Ottawa Scale and ROBINS-I tools.</div></div><div><h3>Results</h3><div>Thirteen studies met the inclusion criteria. Internal distractors demonstrated favorable long-term skeletal stability, with reported relapse rates ranging from 0 % to 15 %. External distractors, most notably the rigid external distractor (RED), produced more advancement but had increased rates of early relapse (as high as 30 %). Bone-borne RED systems had better results compared with tooth-borne systems. The majority of relapses happened during the first 6 months following distraction, most notably in the vertical plane. Le Fort I osteotomy was the most commonly employed surgical procedure.</div></div><div><h3>Conclusion</h3><div>External distractors allowed greater advancement but were associated with relapse rates up to 30 %, especially in the vertical plane. Internal distractors, while offering reduced vector control, provided superior long-term skeletal stability (relapse 0–15 %) and improved patient comfort.</div></div>","PeriodicalId":100364,"journal":{"name":"Dentistry Review","volume":"5 4","pages":"Article 100161"},"PeriodicalIF":0.0,"publicationDate":"2025-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145520418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Generative artificial intelligence in dentistry: A narrative review of current approaches and future challenges","authors":"Fabián Villena ,&nbsp;Claudia Véliz ,&nbsp;Rosario García-Huidobro ,&nbsp;Sebastian Aguayo","doi":"10.1016/j.dentre.2025.100160","DOIUrl":"10.1016/j.dentre.2025.100160","url":null,"abstract":"<div><div>Artificial intelligence (AI) has become a commodity for laypeople and domain experts because of the advent of generative AI (GenAI) models that bridge the usability gap of AI by providing a natural language interface to interact with complex models. GenAI models perform tasks ranging from text generation, such as two-way chat systems, to image and video generation from user-provided textual descriptions. These advancements in AI have impacted Dentistry in multiple aspects. Dental education now benefits from GenAI models by enabling students to address numerous questions through intuitive prompts, receiving instant answers. Dental healthcare practitioners utilize GenAI to gather knowledge quickly and efficiently, improving patient care. In dental research, GenAI supports activities such as academic writing and the discovery of new drugs and therapies. In this narrative review, we summarize the current state of GenAI in dentistry as of 2025, define GenAI models, describe their multiple generation modalities, and discuss their current and potential applications in Dentistry. Finally, we describe the challenges these new technologies impose in our area.</div></div>","PeriodicalId":100364,"journal":{"name":"Dentistry Review","volume":"5 4","pages":"Article 100160"},"PeriodicalIF":0.0,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145134874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application and performance of artificial intelligence in implant dentistry: An umbrella review","authors":"Maryam Emami ,&nbsp;Mohammadjavad Shirani","doi":"10.1016/j.dentre.2025.100159","DOIUrl":"10.1016/j.dentre.2025.100159","url":null,"abstract":"<div><div>This umbrella review evaluates the applications and performance of AI in implant dentistry, comparing its effectiveness to human intelligence. The PICO question addressed was: “In implant dentistry, how does the performance of AI-driven approaches compare to standard references or conventional methods performed by human practitioners?” A comprehensive search was conducted across databases such as PubMed, Embase, Scopus, Web of Science, PROSPERO, Cochrane Library, and Google Scholar until August 2024. Two independent reviewers conducted the screening, data extraction, quality assessment, and certainty evaluation. After screening 12 studies included for qualitative analysis. The majority of studies utilized deep learning (DL) models, and some studies employed traditional machine learning (TML) or simple rule-based algorithms. Most systematic reviews found AI applications and performance promising when compared to human intelligence. However, several challenges were identified, particularly in AI’s accuracy in measuring bone width and height, detecting the inferior alveolar canal, treatment planning, and predicting osseointegration. Although AI shows promise in detecting anatomical landmarks (such as the maxillary sinus), identifying implant systems, and supporting clinical decisions, current models still face significant limitations and should not yet be considered as standalone tools capable of replacing human practitioners.</div></div>","PeriodicalId":100364,"journal":{"name":"Dentistry Review","volume":"5 3","pages":"Article 100159"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144523161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial Intelligence in Dentistry: Advancements in Periodontology and Other Specialties, Diagnosis, Treatment Planning, and Ethical Considerations\"","authors":"Hadeel Mazin Akram","doi":"10.1016/j.dentre.2025.100157","DOIUrl":"10.1016/j.dentre.2025.100157","url":null,"abstract":"<div><div>This narrative review aims to highlight how periodontology is transformed by applying artificial intelligence (AI). AI impacts periodontology in diagnosis, treatment planning, and ethical considerations. AI uses deep learning, genetic algorithms, and different logic systems to offer improved solutions for dental practices, such as in dental restoration, plaque detection, endodontic therapy, dental radiography, detection of malignant tumors, and diagnosis of periodontal diseases. In periodontology, AI has improved diagnoses and treatment plans. This discussion focuses on the advancements of using AI in healthcare and dentistry to identify and manage issues by utilizing different technologies such as convolutional neural networks (CNNs) segmentation models such as U Net and Mask R CNN and classification systems, such as VGG 16.</div><div>This research discusses how AI is utilized to analyze radiography images and salivary biomarkers and classify diseases. It explores the influence of AI on treatment planning and outcome prediction. The ethical implications of AI in periodontology are also discussed, underscoring the significance of data confidentiality and protection. Periodontology can be revolutionized as AI may improve the diagnostic capability and facilintate highly individualized treatment methods to enhance the general quality of the treatment process.</div></div>","PeriodicalId":100364,"journal":{"name":"Dentistry Review","volume":"5 2","pages":"Article 100157"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144221774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of copper incorporated into titanium (cp-Ti) and its alloys (Ti-6Al-4V) and its promising antibacterial effect: a systematic review","authors":"Cícero Andrade Sigilião Celles ,&nbsp;Andréa Cândido dos Reis","doi":"10.1016/j.dentre.2025.100156","DOIUrl":"10.1016/j.dentre.2025.100156","url":null,"abstract":"<div><div>The incorporation of copper (Cu) into titanium (cp-Ti) and its alloys (Ti-6Al-4V) for the manufacture of biomaterials has been a much-studied area since the element has an effective antibacterial capacity against bacteria commonly present in the oral cavity. These changes open the way to more effective, promoting better health outcomes and improving rehabilitation prognosis. This review aimed to answer the question: Does the incorporation of Cu into Ti and its alloys significantly enhance the antibacterial effect, including biofilm inhibition and bacterial viability reduction, compared to pure titanium or copper-free alloys? The materials and methods were based on the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA 2020) registered in the Open Science Framework (OSF) (osf.io/qdu37). The search strategy was followed by PICOS, and the Joanna Briggs Institute (JBI) tool was used to analyze the risk of bias. Once the search had been carried out, 1187 articles were found. After a thorough reading of titles, abstracts, and then the full text, 11 were included. The addition of Cu to Ti and its alloys has shown promising antibacterial potential, with safe use for the human body, with concentrations of 3 and 5 wt. % showing a promising effect. This systematic review highlights the significant potential of Cu, demonstrated by the various benefits Cu offers to combat peri‑implant pathogenic bacteria. However, it also emphasizes the need for continued research to determine a consensus on the ideal concentration and the most effective incorporation methods, which combine antibacterial and pro-osteogenic behavior.</div></div>","PeriodicalId":100364,"journal":{"name":"Dentistry Review","volume":"5 2","pages":"Article 100156"},"PeriodicalIF":0.0,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143885944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emergent periodontal conditions: An overview","authors":"Mark E Peacock,&nbsp;Mira Ghaly,&nbsp;Celine Joyce Cornelius Timothius","doi":"10.1016/j.dentre.2025.100155","DOIUrl":"10.1016/j.dentre.2025.100155","url":null,"abstract":"<div><div>Dental emergency patients present often with periodontal conditions which they deem emergent. Most of these disease states are acute, although some are more associated with chronic ulcerative lesions, such as those seen in desquamative gingivitis cases. Pain or discomfort is the usual reason these patients seek treatment, in addition to swelling, infection, and/or bleeding/suppuration. Oral health care practitioners should have available to them a systematic approach to diagnosis and treatment of these conditions, leading to resolution and improved quality of life for their patients. This article describes common periodontal emergencies, their etiology, and the clinical management of these disorders.</div></div>","PeriodicalId":100364,"journal":{"name":"Dentistry Review","volume":"5 2","pages":"Article 100155"},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143785884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AI-driven evolution in teledentistry: A comprehensive overview of technology and clinical applications","authors":"Richa Kaushik ,&nbsp;Ravindra Rapaka","doi":"10.1016/j.dentre.2025.100154","DOIUrl":"10.1016/j.dentre.2025.100154","url":null,"abstract":"<div><div>This scoping review discusses the current state and future of artificial intelligence (AI) in teledentistry. Teledentistry is a form of telehealth in which dental care is offered via electronic communication across distances due to geographic and financial constraints. The application of AI in teledentistry has made remote diagnosis, treatment scheduling, and patient interaction easier than ever. AI-enabled devices have already shown improved diagnostic performance in generating effective analysis of dental images such as radiographs and intraoral scans to prevent oral diseases in the first place. Automated image analysis in orthodontics, periodontics and prosthodontics, customized treatment plans, and dental prosthesis design are just some of its uses.</div><div>However, there remain a number of limitations, such as lack of infrastructure, clinical readiness, data privacy, and compatibility with current practice management systems. Future technologies, like 5 G connectivity, XR, IoT, edge computing, and blockchain, may prove to further augment AI-enabled teledentistry. Addressing these issues are important for successful and widespread use of AI technologies in the field of remote dentistry.</div><div>The study focuses on how AI can revolutionize the availability, efficacy and performance of teledentistry services. It's also an important reminder that research, ethics and professional training are still needed to properly incorporate AI in order to promote improved dental health.</div></div>","PeriodicalId":100364,"journal":{"name":"Dentistry Review","volume":"5 2","pages":"Article 100154"},"PeriodicalIF":0.0,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143609248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of the anterior open bite using clear aligner therapy and surgery-first: Case example and scoping review of the literature","authors":"Marshall F. Newman ,&nbsp;Joshua Stewart","doi":"10.1016/j.dentre.2025.100153","DOIUrl":"10.1016/j.dentre.2025.100153","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;The anterior open bite is challenging skeletal facial discrepancy and often requires a combined orthodontic and surgical approach to treatment. Traditionally, such approaches have involved use of conventional fixed orthodontic appliances in-preparation, followed by orthognathic surgery, and subsequent refinement of the occlusion with orthodontic treatment after surgery. Surgery-first approaches to treatment of skeletal facial discrepancies exist and have been demonstrated to provide excellent treatment outcomes with often shorter overall treatment times. The use of clear aligner therapy rather than conventional fixed orthodontic appliances has also been described in the treatment of various skeletal facial discrepancies. As providers offer surgery-first and clear aligner treatment options more frequently, a review of the available literature regarding the combination of the two modalities is needed, particularly for treatment of the anterior open bite.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Objectives&lt;/h3&gt;&lt;div&gt;The primary objectives of this report are to systematically review the available literature regarding the use of clear aligner therapy and a surgery-first approach to treatment of the anterior open bite and to provide a case example. Advantages of using clear aligners versus conventional fixed orthodontic appliances will also be discussed.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Eligibility Criteria&lt;/h3&gt;&lt;div&gt;Articles included for review were studies addressing patients with an anterior open bite and the use of a surgery-first approach as well as clear aligner therapy.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Sources of Evidence&lt;/h3&gt;&lt;div&gt;PubMed and Ovid were queried using the terms “clear aligners” AND “von Willebrand OR open bite”; “clear aligners” AND “surgery-first”; and “clear aligners” AND “orthognathic.” Additional references relevant to the review were obtained from the reference lists of available articles ultimately deemed appropriate for inclusion in the review.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;A recent example case of a patient with hemifacial microsomia and an anterior open bite undergoing a combined orthodontic and surgical approach to management is presented for consideration. A scoping review of the literature was undertaken for evaluation of available literature using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Review (PRISMA-ScR).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;Insufficient evidence exists for significant analysis of clear aligner therapy directly compared to conventional fixed orthodontic appliances in patients undergoing surgery-first, as was the strategy used for the case presented. A review of the available literature with reference to updated literature regarding management of patients with an open bite specifically undergoing surgery-first and clear aligner treatment yields one two case series. The results indicate that further study of the subject in question is warranted, but currently ava","PeriodicalId":100364,"journal":{"name":"Dentistry Review","volume":"5 1","pages":"Article 100153"},"PeriodicalIF":0.0,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143445557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Key strategies for evidence synthesis through systematic reviews in Dentistry","authors":"Anirudha Agnihotry ,&nbsp;Radhika Thakkar ,&nbsp;Karanjot S Gill ,&nbsp;Todd Schoenbaum ,&nbsp;Maureen Dobbins ,&nbsp;Richard G Stevenson ,&nbsp;Rachel Couban ,&nbsp;Sagnik Ray","doi":"10.1016/j.dentre.2025.100152","DOIUrl":"10.1016/j.dentre.2025.100152","url":null,"abstract":"<div><div>Systematic reviews in dentistry are increasing in numbers and scope, influencing and informing the overall practice. Quality conduct of these reviews is indispensable. Key strategies should be followed to execute these effectively, starting with assembling the team with all the experts playing the right roles. Formulating the question and registering the review at a protocol registry are important aspects and it should be noted that the right search strategy is followed, where all the databases are thoroughly searched with the guidance from an information specialist. Critical appraisal of the quality of included studies should be performed with an objective tool after the included studies get the data extracted by two reviewers, getting conflicts resolved by a third one. Analyzed data should be schematically presented comprehensively in the results section and suitable conclusions should be drawn, often augmented with generating recommendations for the practice. Dissemination of the results and their implications on practice should be considered a crucial and pivotal part of the review process, as this serves the purpose of the research by creating the impact in the right domains.</div></div>","PeriodicalId":100364,"journal":{"name":"Dentistry Review","volume":"5 1","pages":"Article 100152"},"PeriodicalIF":0.0,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143453940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}