二尖瓣修复或生物假体置换治疗老年风湿性瓣膜病

Baiyu Tian, Jie Han, Yan Li, Yuqing Jiao, Xu Meng
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摘要

目的二尖瓣置换术在老年风湿性瓣膜疾病患者中更为常见。风湿二尖瓣病变的年轻患者解剖结构合适,二尖瓣修复是可行的,但对老年患者仍有争议。我们的研究是比较60岁或以上患者的二尖瓣修复和生物假体置换术。方法回顾性分析我院2014年1月至2016年1月收治的82例(年龄≥60岁)二尖瓣手术(二尖瓣修复或生物假体置换术)患者,其中修复(MVP) 25例,生物假体置换术(MVR) 57例。5年随访分析。结果MVP和MVR的平均年龄分别为64.43岁和67.28岁。两组体外循环时间(P=0.99)、主动脉阻塞时间(P=0.88)差异无统计学意义;MVR组手术死亡率为5.3%,MVP组无手术死亡率(P=0.24)。随访期间MVR共发生6例死亡,其中MACE死亡4例,其他原因死亡2例。MVP组无死亡(P=0.17)。随访期间无重做及其他并发症。结论在60岁及以上风湿性二尖瓣疾病患者中,与生物假体置换术相比,二尖瓣修复术的围手术期和中期结果相同。老年患者风湿性二尖瓣可修复。关键词:二尖瓣功能不全;二尖瓣修复;Bioprosthesis;上了年纪的
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Mitral repair or bioprosthetic replacement for rheumatic valve drseascs in elderly patients
Objective Mitral valve replacement is more frequently performed in elder patients with rheumatic valve diseases. Mitral valve repair may be feasible in young patients with suitable anatomy in rheumatic mitral valve disease, but still controversial in elder patients. Our study was to compare mitral repair to bioprosthetic replacement in patients aged 60 years or older. Methods Eighty two patients(age ≥60 years) underwent mitral valve surgery(mitral repair or bioprosthetic replacement)in our single institution from January 2014 to January 2016 were reviewed, including 25 cases of repair(MVP) and 57 cases of bioprosthetic replacement(MVR). 5 years follow-up oganalysis. Results Mean age in MVP and MVR was 64.43 years and 67.28 years, respectively. There were no statistically differences in extracorporeal circulation time(P=0.99) and aorta blocking time(P=0.88); the operative mortality rate in MVR was 5.3% while none in MVP(P=0.24). During follow-up 6 deaths happened in MVR, 4 of them died from MACE while the other 2 died from other causes. There was no death in MVP(P=0.17). No redo or other complications were found during follow-up. Conclusion In patients aged 60 years or older with rheumatic mitral valve disease, mitral repair is associated with a same perioperative and mid-term result compared with bioprosthetic replacement. Rheumatic mitral valves could be repaired in elderly patients. Key words: Mitral valve insafficiency; Mitral valve repair; Bioprosthesis; Elderly
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