肥胖青少年糖化血红蛋白(HbA1c)水平升高

E. F. Zulissetiana, Elsafani Faddiasya, Nursiah Nasution, Irfannuddin, S. Sinulingga
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摘要

肥胖青少年糖化血红蛋白(HbA1c)升高。儿童和青少年肥胖是一个严重的问题,因为全世界的患病率每年都在增加。儿童和青少年肥胖与糖耐量受损、血脂异常和糖尿病的风险增加有关。糖化血红蛋白(HbA1c)已被推荐作为诊断糖尿病的工具。本研究的目的是确定15-19岁肥胖和非肥胖青少年糖化血红蛋白(HbA1c)水平的差异。本研究是一项采用横断面方法的观察分析研究。这项研究是在巨港第一公立高中和斯里维加亚大学医学院进行的,研究对象包括肥胖青少年和非肥胖青少年。根据年龄和性别测量身体质量指数来确定营养状况。使用Nycocard阅读器检查HbA1c水平。Mann Whitney替代检验的研究结果显示,p值为0000 (p<0.05),肥胖青少年的平均HbA1c水平下降了6.1%,非肥胖青少年的平均HbA1c水平下降了4.7%。综上所述,15-19岁肥胖青少年的HbA1c水平高于非肥胖青少年。
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Increased Levels of Glycated Hemoglobin (HbA1c) in Obese Adolescents
The Increment of Glycated Hemoglobin (HbA1c) in Obese Adolescent. Obesity in childrenand adolescents is a serious concern because the prevalence is increasing every yearthroughout the world. Obesity in children and adolescents is associated with anincreased risk of impaired glucose tolerance, dyslipidemia and diabetes. Glycatedhemoglobin (HbA1c) has been recommended as a diagnostic tool to identify diabetes. Thepurpose of this study was to determine differences in levels of glycated hemoglobin(HbA1c) in obese and non-obese adolescents aged 15-19 years. This study was anobservational analytic study with a cross-sectional approach. The study was conductedin Palembang 1 Public High School and the Faculty of Medicine of Sriwijaya Universityand found 50 subjects consisting of obese adolescents and non-obese adolescent groups.Nutritional status was determined by measuring body mass index according to age andgender. Examination of HbA1c levels was carried out using a Nycocard Reader. Theresults of the study with Mann Whitney alternative test showed a p value of 0,000 (p<0.05) with an average HbA1c level in obese adolescents by 6.1% and an average HbA1clevel in non-obese adolescents by 4.7%. In conclusion, HbA1c levels in obese adolescentsaged 15-19 years are higher than non-obese adolescent.
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