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Quality of Life in Pelvic Organ Prolapse Patients with Operative Therapy at RSUP Dr. Mohammad Hoesin 在 RSUP 接受手术治疗的盆腔器官脱垂患者的生活质量 Mohammad Hoesin 博士
Pub Date : 2024-03-16 DOI: 10.32539/bji.v10i1.183
Mutia Adilah Almenata, Hadrians Kesuma Putra, Septi Purnamasari, Ratih Krisna, A. Martadiansyah
Introduction. Pelvic organ prolapse is a condition where the pelvic organs descend from their original position and protrude into the vagina. This condition causes several complaints in the patients that can interfere with their daily activities and have an impact on their quality of life. One of the treatments that can be given to patients with POP is operative therapy, which one of the goals is to improve patient's quality of life. This study aims to determine the quality of life of pelvic organ prolapse patients with operative therapy at Dr. Mohammad Hoesin Hospital Palembang. Methods. This study used an observational analytical method with a cross-sectional study design. This study consisted of 17 respondents. This study used primary data from interviews using the P-QOL questionnaire guidelines and secondary data from medical records.  Results. This study showed an improvement in the quality of life of pelvic organ prolapse patients in all P-QOL quality of life domains (p<0.05) after receiving operative therapy compared to before receiving operative therapy. Analysis of the effect of confounding factors on the total quality of life score showed that age (p=0.138), BMI (p=0.999), parity (p=0.468), degree of POP (p=0.439), and type of surgery (p=0.814) did not have a significant influence on the quality of life of postoperative POP patients. Conclusion. There was a significant improvement in the quality of life in pelvic organ prolapse patients after receiving operative therapy, and there is no significant relationship between age, BMI, parity, degree of POP, also type of surgery on the quality of life in postoperative POP patients.
简介骨盆器官脱垂是指骨盆器官从原来的位置下降并突出到阴道内。这种情况会导致患者出现多种不适,影响他们的日常活动和生活质量。对 POP 患者的治疗方法之一是手术治疗,其目标之一是改善患者的生活质量。本研究旨在确定在巴伦邦 Mohammad Hoesin 医生医院接受手术治疗的盆腔器官脱垂患者的生活质量。研究方法本研究采用横断面研究设计的观察分析方法。本研究由 17 名受访者组成。本研究使用 P-QOL 问卷指南进行访谈获得的第一手数据和医疗记录获得的第二手数据。 研究结果研究显示,与接受手术治疗前相比,接受手术治疗后盆腔器官脱垂患者在所有 P-QOL 生活质量领域的生活质量均有所改善(P<0.05)。混杂因素对生活质量总分的影响分析表明,年龄(P=0.138)、体重指数(BMI)(P=0.999)、胎次(P=0.468)、POP程度(P=0.439)和手术类型(P=0.814)对术后POP患者的生活质量没有显著影响。结论接受手术治疗后,盆腔器官脱垂患者的生活质量有明显改善,年龄、体重指数、胎次、POP程度和手术类型对术后POP患者的生活质量没有明显影响。
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引用次数: 0
Comparison of Oxygen Saturation Dynamics Between Types of Acute Stroke in Early Hospitalization Period 不同类型急性脑卒中住院初期血氧饱和度动态比较
Pub Date : 2024-03-15 DOI: 10.32539/bji.v10i1.181
Naura Waliya Maharani, Ita Muharram Sari, Patwa Amani
Introduction. Stroke is the number one cause of death and disability in Indonesia. It was found that the incidents of stroke were higher at ages over 45 years. The use of pulse oximeter is an efficient step in monitoring oxygenation in stroke patients. Decreased oxygen levels can cause neurological deficits such as cognitive impairment, causing patients to have problems in attention and executive functions. This study aims to determine the relationship between the type of acute stroke and oxygen saturation in early hospitalization period. Methods. This research was carried out from November to December 2023 at the National Brain Center Hospital, Jakarta, using a cross sectional approach. Information on diagnosis and oxygen saturation values were obtained through medical records, with a total of 70 patients as subjects. Subjects selected through simple random sampling with patients age over 45 years. Statistical analysis used the Mann Whitney test with a significantly different p value <0.05. Results. A total of 68.6% of the subjects were male with ages of 45-59 dominated the subjects at 51.4%. Statistical tests on the type of acute stroke with oxygen saturation values produced a value of p = 0.044 (p < 0.05) on the 3rd day of hospitalization. These results indicate a significant relationship between the type of acute stroke and the oxygen saturation value on the 3rd day of hospitalization. Conclusion. There is a significant correlation between the type of acute stroke and oxygen saturation in the 3rd day of hospitalization.
导言。在印度尼西亚,中风是导致死亡和残疾的头号原因。研究发现,45 岁以上的中风患者发病率较高。使用脉搏血氧仪是监测中风患者血氧含量的有效步骤。血氧水平下降会导致神经功能缺损,如认知障碍,使患者在注意力和执行功能方面出现问题。本研究旨在确定急性中风类型与住院早期血氧饱和度之间的关系。研究方法本研究于 2023 年 11 月至 12 月在雅加达国立脑科中心医院进行,采用横断面方法。通过病历获取诊断信息和血氧饱和度值,共有 70 名患者作为研究对象。受试者通过简单随机抽样选出,患者年龄在 45 岁以上。统计分析采用 Mann Whitney 检验,P 值小于 0.05 时差异显著。结果68.6%的受试者为男性,年龄在 45-59 岁之间的受试者占 51.4%。住院第三天,急性中风类型与血氧饱和度值的统计检验结果为 p = 0.044(p < 0.05)。这些结果表明,急性中风类型与住院第 3 天的血氧饱和度值之间存在重要关系。结论急性脑卒中类型与住院第 3 天的血氧饱和度之间存在明显相关性。
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引用次数: 0
Blood Transfusion Incidence and Sociodemographics Relationship with Anxiety Levels of Thalassemia Major Parents 输血发生率和社会人口统计学与地中海贫血症父母焦虑水平的关系
Pub Date : 2024-03-06 DOI: 10.32539/bji.v10i1.177
Thalassemia Major, Parents Safyudin, Dita Tri Ramadianti, Liniyanti D. Oswari, Eka Handayani Oktharina
Introduction. Thalassemia is inherited anemia in an autosomal recessive manner with a disruption in hemoglobin synthesis that causes a decreased amount of hemoglobin and anemia. Routine blood transfusions carried out by sufferers and parents' sociodemographic factors can cause an increased psychological burden on the patient's parents. This study investigated the relationship between the incidence of blood transfusions in pediatric patients and parents' sociodemographics with the anxiety level of parents in pediatric thalassemia major patients at RSMH Palembang. This study used an observational analytical method with a cross-sectional study design. Methods. This study used an observational analytical method with a cross-sectional study design. This study consisted of 42 respondents. This study used primary data from interviews and filling out the Z-SAS questionnaire and secondary data from medical records. Results. The distribution of blood transfusion found in thalassemia major children who had transfusions £1 time/month was 40.5%. Based on sociodemographics, 81% of respondents were women, 26.2% had a low level of education, 28.6% were in early adulthood, 61.9% had less income, 81% had 1 child, and 14.3% had thalassemia Major children diagnosed £1 year. The level of anxiety that dominated the results was normal/not anxious (72.8%) and mild anxiety (26.2%). (P Value= 0.305; 0.174; 1.00; 0.095; 0.158; 0.657; 0.644). Conclusion. There was no relation between blood transfusion incidence in children with thalassemia major and sociodemographic of parents with anxiety levels of children with thalassemia major parents in RSMH Palembang.
简介地中海贫血是一种常染色体隐性遗传性贫血,血红蛋白合成障碍导致血红蛋白量减少和贫血。患者的常规输血和父母的社会人口因素会加重患者父母的心理负担。本研究调查了巴伦邦皇家医学院附属医院(RSMH Palembang)小儿重型地中海贫血症患者输血发生率和家长社会人口学因素与家长焦虑程度之间的关系。本研究采用横断面研究设计的观察分析方法。研究方法本研究采用观察分析法和横断面研究设计。本研究由 42 名受访者组成。本研究使用了通过访谈和填写 Z-SAS 问卷获得的第一手数据,以及通过医疗记录获得的第二手数据。研究结果在地中海贫血重症患儿中,每月输血 1 英镑的比例为 40.5%。从社会人口统计学来看,81%的受访者为女性,26.2%的受访者受教育程度较低,28.6%的受访者处于成年早期,61.9%的受访者收入较低,81%的受访者有一个孩子,14.3%的受访者有1英镑的重型地中海贫血患儿。结果显示,焦虑程度以正常/不焦虑(72.8%)和轻度焦虑(26.2%)为主。(P值= 0.305; 0.174; 1.00; 0.095; 0.158; 0.657; 0.644)。结论地中海贫血患儿的输血发生率与巴伦邦皇家医疗中心地中海贫血患儿家长的社会人口学和焦虑水平之间没有关系。
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引用次数: 0
Inhibition Effect of N-Hexane Extract of Cherry Mistletoe Leaves (Dendropthtoe pentandra (L) Miq.) on Xanthine Oxidase 樱桃槲叶(Dendropthoe pentandra (L) Miq.)N-己烷提取物对黄嘌呤氧化酶的抑制作用
Pub Date : 2024-03-01 DOI: 10.32539/bji.v10i1.175
Mario Saputra, S. Sinulingga, Subandrate Subandrate
Introduction. Cherry leaf extract has been found to have the potentiality to impede the xanthine oxidase enzyme. It is believed that cherry mistletoe leaves also possess similar properties as they are hemiparasites of their host. This study aims to determine the inhibition effect of N-Hexane extract of mistletoe cherry leaves on the xanthine oxidase. Methods. This research was conducted as an experimental in-vitro study. Cherry mistletoe leaves were extracted by N-Hexane solvent. The extract was divided into five doses, i.e. 40 mg/L, 20 mg/L, 10 mg/L, 5 mg/L, and 2.5 mg/L. Phytochemical screening was conducted to identify secondary metabolites. The impact of xanthine oxidase inhibition was quantified using a UV-vis spectrophotometer at wavelength of 400 nm. Results. N-Hexane extract of cherry mistletoe leaves contains alkaloids and triterpenoids. N-Hexane extract of mistletoe cherry leaves at a dose of 40 mg/L, 20 mg/L, 10 mg/L, 5 mg/L, and 2.5 mg/L was able to inhibit the xanthine oxidase enzyme with the line equation y = -0.2543x+ 91.305. The IC50 value for the N-Hexane extract of cherry mistletoe leaves is 162 mg/L Conclusion. N-Hexane extract of cherry mistletoe leaves has the potency to inhibit the xanthine oxidase enzyme in the medium category.
简介研究发现,樱桃叶提取物具有抑制黄嘌呤氧化酶的潜力。据信,樱花槲寄生叶也具有类似的特性,因为它们是宿主的半寄生虫。本研究旨在确定槲寄生樱桃叶 N-己烷提取物对黄嘌呤氧化酶的抑制作用。研究方法本研究是一项体外实验研究。用正己烷溶剂提取槲寄生樱桃叶。提取物分为五种剂量,即 40 毫克/升、20 毫克/升、10 毫克/升、5 毫克/升和 2.5 毫克/升。进行了植物化学筛选,以确定次生代谢物。使用波长为 400 nm 的紫外可见分光光度计对黄嘌呤氧化酶抑制作用进行量化。结果樱花槲寄生叶的正己烷提取物含有生物碱和三萜类化合物。40毫克/升、20毫克/升、10毫克/升、5毫克/升和2.5毫克/升剂量的槲寄生叶正己烷提取物能够抑制黄嘌呤氧化酶,线性方程为y = -0.2543x+ 91.305。樱花槲寄生叶的 N-己烷提取物的 IC50 值为 162 毫克/升。樱桃槲寄生叶的 N-己烷提取物对中等浓度的黄嘌呤氧化酶具有抑制作用。
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引用次数: 0
Risk of Vitamin D Deficiency in Medical Students Based on The Characteristics of Food Intake and Sun Exposure 基于食物摄入和日光照射特征的医学生维生素 D 缺乏风险
Pub Date : 2024-03-01 DOI: 10.32539/bji.v10i1.173
Vienna Dwinda Putri, Syarif Husin, Ardesy Melizah Kurniati, Julius Anzar, Z. Maritska, Syarinta Adenina
Introduction. The need for Vitamin D can be fulfilled through direct synthesis from Vitamin D stores in the skin with the help of ultraviolet B rays. Therefore, sufficient Vitamin D intake and sun exposure are needed. Most of the activities of medical students on campus are indoors from morning to evening, so it is suspected that there is a risk of Vitamin D deficiency. The purpose of this study was to identify the risk of Vitamin D deficiency based on the characteristics of Vitamin D from food intake and sun exposure in Faculty of Medicine students, Universitas Sriwijaya. Methods. This research was a descriptive study using a questionnaire and observation. Age, sex, BMI and use of related drugs were recorded. The food survey method used was the repeated food recall which was then analyzed using Nutrisurvey 2007. Subjects filled out a questionnaire to obtain data on exposure scores and sun protection scores. The research subjects were students of the Faculty of Medicine, Universitas Sriwijaya who were willing to sign informed consent and were present at the time of sampling. Results. The results from the data of 259 subjects showed that 98.8% of the subjects did not meet their vitamin D intake needs, with an average consumption of 123 ± 142 IU. Types of food that contribute the most Vitamin D are catfish (40%) and eggs (20%). None of the subjects took supplements containing Vitamin D. Sun exposure was sufficient for most subjects (62.9%), but most subjects were at risk of deficiency due to the use of sun protection (62.2%) Conclusion. There is a risk of deficiency in most medical students due to a lack of Vitamin D intake and the use of sun protection.
介绍。人体对维生素 D 的需求可通过皮肤中储存的维生素 D 在紫外线 B 的帮助下直接合成。因此,需要摄入足够的维生素 D 和接受阳光照射。医学生在校园里的活动大多从早到晚都在室内进行,因此怀疑存在维生素 D 缺乏的风险。本研究的目的是根据斯里维加亚大学医学系学生从食物摄入和阳光照射中获取维生素 D 的特点,确定维生素 D 缺乏的风险。研究方法本研究是一项描述性研究,采用问卷调查和观察法。对年龄、性别、体重指数和相关药物的使用情况进行了记录。采用的食物调查方法是重复食物回忆,然后使用 Nutrisurvey 2007 进行分析。研究对象填写了一份调查问卷,以获得有关暴露得分和防晒得分的数据。研究对象为斯里维加亚大学医学院的学生,他们愿意签署知情同意书,并在抽样时在场。研究结果259名受试者的数据结果显示,98.8%的受试者没有满足维生素D的摄入需求,平均摄入量为123 ± 142 IU。摄入维生素 D 最多的食物是鲶鱼(40%)和鸡蛋(20%)。大多数受试者(62.9%)晒太阳的时间足够,但大多数受试者由于使用防晒措施而面临缺乏维生素 D 的风险(62.2%)。由于缺乏维生素 D 摄入量和使用防晒措施,大多数医学生都有缺乏维生素 D 的风险。
{"title":"Risk of Vitamin D Deficiency in Medical Students Based on The Characteristics of Food Intake and Sun Exposure","authors":"Vienna Dwinda Putri, Syarif Husin, Ardesy Melizah Kurniati, Julius Anzar, Z. Maritska, Syarinta Adenina","doi":"10.32539/bji.v10i1.173","DOIUrl":"https://doi.org/10.32539/bji.v10i1.173","url":null,"abstract":"Introduction. The need for Vitamin D can be fulfilled through direct synthesis from Vitamin D stores in the skin with the help of ultraviolet B rays. Therefore, sufficient Vitamin D intake and sun exposure are needed. Most of the activities of medical students on campus are indoors from morning to evening, so it is suspected that there is a risk of Vitamin D deficiency. The purpose of this study was to identify the risk of Vitamin D deficiency based on the characteristics of Vitamin D from food intake and sun exposure in Faculty of Medicine students, Universitas Sriwijaya. Methods. This research was a descriptive study using a questionnaire and observation. Age, sex, BMI and use of related drugs were recorded. The food survey method used was the repeated food recall which was then analyzed using Nutrisurvey 2007. Subjects filled out a questionnaire to obtain data on exposure scores and sun protection scores. The research subjects were students of the Faculty of Medicine, Universitas Sriwijaya who were willing to sign informed consent and were present at the time of sampling. Results. The results from the data of 259 subjects showed that 98.8% of the subjects did not meet their vitamin D intake needs, with an average consumption of 123 ± 142 IU. Types of food that contribute the most Vitamin D are catfish (40%) and eggs (20%). None of the subjects took supplements containing Vitamin D. Sun exposure was sufficient for most subjects (62.9%), but most subjects were at risk of deficiency due to the use of sun protection (62.2%) Conclusion. There is a risk of deficiency in most medical students due to a lack of Vitamin D intake and the use of sun protection.","PeriodicalId":52711,"journal":{"name":"Biomedical Journal of Indonesia","volume":"17 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140278012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knowledge Level of Dry Skin Care in The Elderly at The Koto Tangah Regional Health Center Koto Tangah 地区医疗中心老年人对干性皮肤护理的了解程度
Pub Date : 2024-03-01 DOI: 10.32539/bji.v10i1.169
Fuji Lestari Kursiussamawati, Irma Primawati, S. Sriwahyuni
Introduction. The occurrence of dry skin in the elderly requires good and extra skin care. The incidence and severity of dry skin increases with age. Dry skin conditions in the elderly can cause discomfort and can even cause disease, such as atopic dermatitis which is a disease caused by inflammation of the skin. This research aims to determine the level of knowledge of dry skin care in the elderly at the Koto Tangah Health Center in the city of Padang. Methods. This research was a descriptive observational study with a cross-sectional design. The sample in this study was selected by technique consecutive sampling and this research requires a minimum of 100 samples. Results. The knowledge level of dry skin care of the respondents is mostly in the medium category  (62%), the age of the majority of respondents was in the age category of 60-70 years (65%), the sex of the majority of respondents was male (53%), most respondents had primary school education (56%), worked as laborer (26%), and live with their families (83%). Conclusion. The level of knowledge of nursing for most of the elderly dry skin is in the medium category.
介绍。老年人皮肤干燥,需要做好额外的皮肤护理。皮肤干燥的发生率和严重程度会随着年龄的增长而增加。老年人皮肤干燥会引起不适,甚至会导致疾病,例如特应性皮炎,这是一种由皮肤炎症引起的疾病。本研究旨在确定巴东市 Koto Tangah 健康中心的老年人对干燥皮肤护理知识的了解程度。研究方法本研究是一项横断面设计的描述性观察研究。本研究的样本是通过连续抽样技术选出的,本研究至少需要 100 个样本。研究结果受访者的干性皮肤护理知识水平大多属于中等水平(62%),大多数受访者的年龄在 60-70 岁之间(65%),大多数受访者的性别为男性(53%),大多数受访者受过小学教育(56%),当过工人(26%),与家人住在一起(83%)。结论大多数干性皮肤老人的护理知识水平属于中等水平。
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引用次数: 0
Association Between Patient Characteristics and Histopathological Features of Lung Cancer At RSUP Dr. Mohammad Hoesin Palembang 患者特征与肺癌组织病理学特征之间的关系在RSUP Mohammad Hoesin Palembang
Pub Date : 2023-11-02 DOI: 10.32539/bji.v9i2.149
Isnani Nur I, Susilawati Susilawati, Soilia Fertilita
Introduction. Lung cancer is the uncontrolled growth of malignant cells by the body in lung tissue and is caused by genetic mutations and changes in protein synthesis in normal cells. Histopathological features of lung cancer include squamous cell carcinoma, adenocarcinoma, small cell carcinoma, and other types. Early detection, as well as prevention, needs to be done in high-risk communities with the aim of reducing the number of events. This study aims to determine the relationship between sociodemographic factors and histopathological features of lung cancer. Methods. This study is an analytic observational study with a cross-sectional design. The research sample is in the form of secondary data from the Department of Anatomical Pathology and Medical Record Installation for 2019-2021. The research was conducted at Dr. Mohammad Hoesin Palembang. The sampling technique was carried out by total sampling. Results. Most of the respondents were in the age group >45 years (84.1%), male (78.3%), had no history of smoking (60.9%), the predominant main complaint was shortness of breath (63, 8%), the most common histopathological picture is adenocarcinoma. There was no significant relationship between age (p=0.998), gender (p=0.736), smoking history (p=0.572) and histopathological features of lung cancer patients. Conclusion. There was no significant relationship between age, sex and smoking status on the histopathological features of lung cancer.
介绍。肺癌是机体在肺组织中恶性细胞不受控制的生长,由正常细胞的基因突变和蛋白质合成改变引起。肺癌的组织病理学特征包括鳞状细胞癌、腺癌、小细胞癌和其他类型。需要在高风险社区进行早期发现和预防,目的是减少事件的数量。本研究旨在探讨社会人口学因素与肺癌组织病理学特征之间的关系。方法。本研究是一项横断面设计的分析性观察研究。研究样本为2019-2021年解剖病理和病历安装部的二手数据。这项研究是在Mohammad Hoesin Palembang博士进行的。采样技术采用全采样法。结果。年龄≥45岁(84.1%),男性(78.3%),无吸烟史(60.9%),主要主诉为呼吸短促(63.8%),最常见的组织病理表现为腺癌。肺癌患者的年龄(p=0.998)、性别(p=0.736)、吸烟史(p=0.572)与组织病理特征无显著相关。结论。年龄、性别、吸烟状况与肺癌的组织病理特征无明显关系。
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引用次数: 0
Quality of Life in Elderly with Stress Urinary Incontinence at Elderly Posyandu Dempo Health Center Palembang 巨港老年Posyandu Dempo健康中心老年压力性尿失禁患者的生活质量
Pub Date : 2023-11-02 DOI: 10.32539/bji.v9i2.156
Namira Amalia, Amir Fauzi, Hadrians Kesuma Putra
Introduction. Urinary incontinence is the loss of a person's ability to control urination. This condition is a common health problem that is often found in the elderly, especially in women. Stress urinary incontinence is one of the urinary incontinence that is often found due to increased intra-abdominal pressure. Urinary incontinence can have a negative effect on the quality of life of the elderly. This study aims to provide an overview of the quality of life in elderly women with stress urinary incontinence. Method. This study is observational descriptive research. The data was obtained from interviews with elderly women at the Elderly Posyandu Dempo Health Center Palembang in the period October – November 2022, who met the inclusion and exclusion criteria. Results. The samples in this study have more demographic characteristics of the elderly group at the age 60-69 years (70%), last education level in elementary school (47.5%), married (57.5%), and normal BMI (53.8%). This study found elderly women with a history of parity ≥ 2 (81.3%), and vaginal delivery (75%). It was found that elderly women with stress urinary incontinence had a moderate quality of life (82.5%) and moderate results in all domains of quality of life, namely physical health (46.3%), psychology (62.5%), social relations (53.7%), and the environment (62.5%). Conclusion. Elderly women with stress urinary incontinence at the Elderly Posyandu of the Dempo Palembang Health Center have a moderate quality of life and moderate impact on the domains of physical health, psychology, social relations, and the environment.
介绍。尿失禁是指一个人失去控制排尿的能力。这种情况是一种常见的健康问题,常见于老年人,尤其是妇女。压力性尿失禁是由于腹内压力增高而引起的尿失禁之一。尿失禁会对老年人的生活质量产生负面影响。本研究旨在对老年女性压力性尿失禁患者的生活质量进行综述。方法。本研究为观察性描述性研究。数据来自2022年10月至11月期间在巨港老年Posyandu Dempo保健中心对符合纳入和排除标准的老年妇女的访谈。结果。本研究样本的人口学特征更多为60-69岁高龄组(70%)、小学末文化程度组(47.5%)、已婚组(57.5%)、BMI正常组(53.8%)。本研究发现有产次≥2次(81.3%)和阴道分娩史(75%)的老年妇女。结果发现,老年妇女压力性尿失禁的生活质量中等(82.5%),生活质量各领域的结果均为中等,即身体健康(46.3%)、心理(62.5%)、社会关系(53.7%)和环境(62.5%)。结论。在登波巨港保健中心的老年护理中心,患有压力性尿失禁的老年妇女的生活质量一般,对身体健康、心理、社会关系和环境的影响也不大。
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引用次数: 0
Long-Term Growth and Development Monitoring Of Children With Rhesus Hemolytic Disease of The Newborn 新生儿恒河溶血病患儿的长期生长发育监测
Pub Date : 2023-11-02 DOI: 10.32539/bji.v9i2.162
Nia Nurul Aziza, Dita Setiati, Patwa Amani
Rhesus hemolytic disease of the newborn (RHDN) occurs due to alloimmunization of maternal red blood cells. Complications of RHDN in infants can lead to hyperbilirubinemia, kernicterus, and anemia. In Indonesia, RHDN prevention has not been a common activity so it is very important for pediatricians to recognize early signs of an infant with severe anemia and severe hyperbilirubinemia, to prevent long-term mortality and morbidity. A case with longitudinal observation of long-term growth and development of a child with a history of RHDN has been reported. Throughout the monitoring carried out, the child did not experience serious problems in the medical field but showed disorders or developmental delays that did not improve over time with various therapeutic efforts. Based on a serial monitoring and treatment data that has been carried out on the child, we assumed there has been permanent brain damage caused by hyperbilirubinemia conditions accompanied by co-morbid sepsis. Brain damage is characterized by low DQ values from the beginning, progressive head circumference leads to microcephaly conditions and the presence of brain defects in the form of arachnoid cysts. The management of child development disorders with RHDN to date has not shown encouraging results. Therefore, experts have shifted their focus towards preventive measures, such as intra-uterine fetal transfusion, which has been shown to significantly decrease the occurrence of RHDN-related child development disorders over the past decade.
新生儿的恒河溶血病(RHDN)是由于母体红细胞的异体免疫而发生的。婴儿RHDN的并发症可导致高胆红素血症、核黄疸和贫血。在印度尼西亚,RHDN预防并不是一项普遍的活动,因此儿科医生识别患有严重贫血和严重高胆红素血症的婴儿的早期症状,以防止长期死亡率和发病率是非常重要的。本文报道了一例对有RHDN病史的儿童进行长期生长发育的纵向观察。在整个监测过程中,该儿童在医学领域没有出现严重问题,但表现出紊乱或发育迟缓,经过各种治疗努力,这些问题并没有随着时间的推移而得到改善。根据对该儿童进行的一系列监测和治疗数据,我们假设该儿童存在由高胆红素血症引起的永久性脑损伤,并伴有合并症败血症。脑损伤的特点是从一开始就低DQ值,逐渐的头围导致小头畸形和蛛网膜囊肿形式的脑缺陷的存在。迄今为止,RHDN对儿童发育障碍的管理尚未显示出令人鼓舞的结果。因此,专家们已将重点转向预防措施,如子宫内胎儿输血,这已被证明在过去十年中显著减少了与rhdn相关的儿童发育障碍的发生。
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引用次数: 0
Clinical Symptoms of Carpal Tunnel Syndrome and Its Correlation With Vitamin D Level 腕管综合征临床症状及其与维生素D水平的关系
Pub Date : 2023-11-02 DOI: 10.32539/bji.v9i2.165
Andira Larasari, Rima Anindita, Andini Aswar, Yudhisman Imran
Carpal tunnel syndrome (CTS) is a common entrapment neuropathy of the peripheral nerves in the upper extremities that is often found in workers. Nerve conduction disorders occur due to compression of the carpal tunnel, resulting in motor and sensory symptoms in the hands and wrists. This causes clinical symptoms and characteristic neurophysiological examinations. Vitamin D is an intrinsic factor that causes CTS which is now widely studied and is expected to play a role in the choice of CTS management. Vitamin D is important for maintaining health and has been found to have neuroprotective function. Several studies have proven the association between vitamin D deficiency and the incidence of CTS. Supplementation can improve clinical symptoms and neurophysiological features of mild to moderate CTS patients.
腕管综合征(Carpal tunnel syndrome, CTS)是一种常见于工人的上肢周围神经的压迫性神经病变。神经传导障碍由于腕管受压而发生,导致手和手腕出现运动和感觉症状。引起临床症状和特征性神经生理检查。维生素D是引起CTS的内在因素,目前已被广泛研究,并有望在CTS治疗的选择中发挥作用。维生素D对维持健康很重要,并被发现具有神经保护功能。一些研究已经证明了维生素D缺乏和CTS发病率之间的联系。补充可改善轻中度CTS患者的临床症状和神经生理特征。
{"title":"Clinical Symptoms of Carpal Tunnel Syndrome and Its Correlation With Vitamin D Level","authors":"Andira Larasari, Rima Anindita, Andini Aswar, Yudhisman Imran","doi":"10.32539/bji.v9i2.165","DOIUrl":"https://doi.org/10.32539/bji.v9i2.165","url":null,"abstract":"Carpal tunnel syndrome (CTS) is a common entrapment neuropathy of the peripheral nerves in the upper extremities that is often found in workers. Nerve conduction disorders occur due to compression of the carpal tunnel, resulting in motor and sensory symptoms in the hands and wrists. This causes clinical symptoms and characteristic neurophysiological examinations. Vitamin D is an intrinsic factor that causes CTS which is now widely studied and is expected to play a role in the choice of CTS management. Vitamin D is important for maintaining health and has been found to have neuroprotective function. Several studies have proven the association between vitamin D deficiency and the incidence of CTS. Supplementation can improve clinical symptoms and neurophysiological features of mild to moderate CTS patients.","PeriodicalId":52711,"journal":{"name":"Biomedical Journal of Indonesia","volume":"38 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135974234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Biomedical Journal of Indonesia
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