大气污染物对儿童哮喘发病的影响

B. Garty, E. Kosman, E. Ganor, Niv Alon, Neta Kibilis, J. Garty, M. Mimouni, Yoav Waise
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引用次数: 4

摘要

研究了空气污染物、天气条件、空气中的花粉和孢子对急性哮喘患儿急诊室就诊的影响。进行为期一年的回顾性研究。收集了每日空气污染物浓度、空气中过敏原和天气条件的数据,并与特拉维夫附近施耐德医疗中心2431名哮喘儿童(1-18岁)的急诊就诊数据进行了比较。哮喘儿童急诊室就诊与测量的臭氧浓度和极端环境温度呈负相关。高气压与NO2和SO2浓度呈正相关。哮喘儿童的急诊发病率在9月份特别高,恰逢学年的开始。当将9月排除在年度计算之外时,急诊室就诊与环境因素之间的相关性增加。急诊就诊的差异49%是由O3单独解释的,46%是由NO2单独解释的,54%是由O3+NO2解释的,31%是由天气参数解释的。58%的变化可以用空气污染物和天气参数的结合来解释。空气中的颗粒物与急诊室就诊没有任何有意义的相关性。与严重哮喘发作相关的主要因素是高NO2和SO2。与O3的负相关表明,在一定浓度下,O3可能有有益的作用。在学年开始的时候,急诊室的访问量特别高,这可能与病毒感染的增加以及情绪压力有关。
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Effects of Atmospheric Pollutants on Children Asthma Outbreaks
The effects of air pollutants, weather conditions, airborne pollen and spores on the incidence of emergency room (ER) visits of children for acute asthma attacks were investigated. One-year retrospective study was done. Data on daily concentrations of air pollutants, airborne allergens and weather con- ditions were collected and compared with the ER visits of 2431 asthmatic children (age 1-18 years) in the Schneider Medical Center, near Tel Aviv. ER visits of asthmatic children showed a negative correlation with the measured O3 concentrations and with extreme am- bient temperatures. A positive correlation was found with high barometric pressure with NO2 and SO2 concentrations. An exceptionally high incidence of ER visits of asthmatic children was observed during September, coinciding with the be- ginning of the school year. When September was excluded from the annual calculations the correlation between ER visits and environmental factors increased. 49% of the variance of ER visits were explained by O3 alone, 46% by NO2 alone, 54% by O3+NO2, and 31% by weather parameters. 58% of the variation was explained by the combination of air pollut- ants and weather parameters. Airborne particulates did not show any meaningful correlation with ER visits. The major factors associated with severe asthma attacks were high NO2 and SO2. The negative correlation with O3 implies that at certain concentrations, O3 may have a beneficial effect. The particularly high number of ER visits at the beginning of the school year was presumably associated with an increase in viral infections combined with emotional stresses.
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