骆驼(Camelus dromedarius)尿液对多重耐药细菌的特殊治疗特性

V. Bhardwaj
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摘要

骆驼尿的治疗用途已经知道了几个世纪,在早期的民间传说中发现了它用于治疗目的的证据。它被用来治疗不同的疾病;然而,尿液的显著治疗效益尚未经过严格的科学评估。探索骆驼尿的利用对确定其在制药工业中的功效具有重要意义。本研究考察了骆驼尿液对5种人类致病菌的作用,以确定其对多重耐药微生物的作用。探针采用琼脂孔扩散法。采用多药耐药菌株枯草芽孢杆菌(ATCC 6633)、大肠杆菌(ATCC 8739)、肠沙门氏菌(ATCC 14028)、金黄色葡萄球菌(ATCC 6538)、铜绿假单胞菌(ATCC 27853)进行研究。以环丙沙星为标准品。对肠沙门氏菌的最大抑制区为33±0.2 mm。此外,多药耐药(MDR)菌株大肠杆菌、铜绿假单胞菌和金黄色葡萄球菌被骆驼尿液强烈抑制。此外,耐多药菌株对枯草芽孢杆菌也有抑制作用。骆驼尿液所显示的治疗作用的效力,建议它们用于对抗多重耐药微生物。在这项研究工作中,已经提出了科学证据,支持骆驼尿液的治疗能力,骆驼尿液对被测微生物显示出潜在的抗菌活性,可能是新的抗菌药物的潜在来源。
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Peculiar Therapeutic Property of Camel’s (Camelus dromedarius) Urine Against Multidrug Resistant Bacteria
The remedial use of camel urine has been known for centuries, with evidence of its use for curative purposes found in early folklore. It has been used to cure different diseases; however, the significant therapeutic benefits of urine have yet to undergo rigorous scientific evaluation. The exploration of the use of camel urine is of great interest to determine their efficacy in pharmaceutical industry. This study investigated the effect of camel’s urine against five human pathogenic bacteria, to determine their efficacy against multidrug resistant microbes. The probe was done by agar well diffusion method. Multidrug resistant (MDR) strains of Bacillus subtilis (ATCC 6633), E. coli (ATCC 8739), Salmonella enterica (ATCC 14028), Staphylococcus aureus (ATCC 6538), Pseudomonas aeruginosa (ATCC 27853) were used in the study. Ciprofloxacin was used as standard. Maximum zone of inhibition was observed with Salmonella enterica which is 33 ± 0.2 mm. Additionally, Multidrug resistant (MDR) strains of E. coli, Pseudomonas aeruginosa and Staphylococcus aureus was strongly inhibited by camel’s urine. Moreover, MDR strains of Bacillus subtilis, also shows inhibition. The potency shown by camel’s urine for therapeutic action, recommends their use against multidrug resistant microorganisms. In this research work, scientific evidence has been presented that supports, therapeutic capabilities of camel’s urine which exhibited a potential antibacterial activity against the tested microorganisms and could be a potential source of new antimicrobial agents.
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