基于多尺度关键点估计方法的小数据集对特发性脊柱侧凸的脊柱曲线评估

Tianyun Liu, Yukang Yang, Yu Wang, Ming Sun, Wenhui Fan, Cheng Wu, C. Bunger
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引用次数: 3

摘要

特发性脊柱侧凸(IS)是最常见的脊柱畸形类型,它会导致严重的疼痛和潜在的心肺损伤。IS的临床诊断和治疗策略在很大程度上取决于脊柱曲度的影像学评估。随着深度学习对图像识别的改进,基于学习的方法可以应用于促进临床决策。然而,这些方法通常需要足够大的训练数据集和精确的注释,这是非常费力和耗时的,特别是对于医学图像。此外,严重IS的医学图像往往包含模糊和闭塞的部分,这给脊柱曲线的严格标注增加了难度。为了解决这些问题,我们利用点注释方法对医学图像进行简单的注释,而不是精确的注释。然后,我们设计了一种多尺度关键点估计方法,结合挤压和激励(SE)块来提高模型的表示能力,实现了在没有大数据集的情况下对脊柱曲线的评估。该方法首次采用姿态估计框架对脊柱关键点进行检测,标注简单,数据量小。最后,我们在收集的临床数据集上进行了实验,结果表明我们的方法优于主流方法。
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Spinal curve assessment of idiopathic scoliosis with a small dataset via a multi-scale keypoint estimation approach
Idiopathic scoliosis (IS) is the most common type of spinal deformity, which leads to severe pain and potential heart and lung damage. The clinical diagnosis and treatment strategies for IS highly depend on the radiographic assessment of spinal curve. With improvements in image recognition via deep learning, learning-based methods can be applied to facilitate clinical decision-making. However, these methods usually require sufficiently large training datasets with precise annotation, which are very laborious and time-consuming especially for medical images. Moreover, the medical images of serious IS always contain the blurry and occlusive parts, which would make the strict annotation of the spinal curve more difficult. To address these challenges, we utilize the dot annotations approach to simply annotate the medical images instead of precise annotation. Then, we design a multi-scale keypoint estimation approach that incorporates Squeeze-and-Excitation(SE) blocks to improve the representational capacity of the model, achieving the assessment of spinal curve without large-size dataset. The proposed approach uses pose estimation framework to detect keypoints of spine with simple annotation and small-size dataset for the first time. Finally, we conduct experiments on a collected clinical dataset, and results illustrate that our approach outperforms the mainstream approaches.
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