公民死亡器官捐献肾移植后肺粘膜感染的临床分析

L. Ding
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摘要

目的探讨公民死亡器官捐献肾移植后肺粘膜感染的原因、诊断和治疗。方法回顾性分析2015年1月至2019年6月我院实施器官捐献肾移植术后4例典型肺粘膜感染的病因、诊断及治疗情况。结果4例临床症状严重的患者中,3例经及时对症治疗后存活,1例因毛霉侵犯肺血管及血胸死亡。结论公民死亡器官捐献肾移植后肺粘膜感染迅速、侵袭性强,甚至可致死亡。为了挽救移植受者的生命,及时停用或降低免疫抑制剂的剂量,根据临床情况单独或联合使用抗毛霉的抗菌药物至关重要。关键词:肾移植;肺部感染;毛霉菌;诊断;治疗
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Clinical analysis of pulmonary mucor infection after kidney transplantation from citizens' death organ donation
Objective To explore the causes, diagnosis and treatment of pulmonary mucor infection after kidney transplantation from citizens' death organ donation. Methods A retrospective analysis was performed for the causes, diagnosis and treatment of 4 cases of typical pulmonary mucor infection since the implementation of organ donation and kidney transplantation after death at our hospital from January 2015 to June 2019. Results Among 4 patients with severe clinical symptoms, 3 survived after timely symptomatic treatments and 1 patient died due to mucor invasion of pulmonary blood vessels and hemothorax. Conclusions Pulmonary mucor infection is often rapid, aggressive and even fatal after kidney transplantation from citizens' death organ donation. For saving the life of transplant recipients, it is vital to save to withdraw or lower the dose of immunosuppressive agents timely and use antibacterial agents against mucor alone or jointly according to clinical condition. Key words: Kidney transplantation; Pulmonary infection; Mucor; Diagnosis; Treatment
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