血红蛋白D特征-一种罕见的血红蛋白病:1例报告

R. Sultana, T. Gosh
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摘要

*通讯:孟加拉国chattagram Maa-O-Shishu医院医学院检验医学系教授Razia Sultana博士。摘要本病例表现为血红蛋白D特征(Hb-D),这是孟加拉国的一种罕见疾病。血红蛋白D为杂合状态,曾到马石树总医院检验医学系进行血红蛋白电泳。我们的病人是来自孟加拉国Noakhali的9岁女孩。临床表现沉默,无脾肿大。外周血膜为小细胞性低色贫血,Hb毛细管电泳(CE)显示Hb D特征。在家庭筛查中,她的父亲是Hb E特征,母亲是Hb D特征,妹妹是正常Hb研究。血红蛋白D和血红蛋白E的复合杂合性可能出现在母亲的后续妊娠中。
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Haemoglobin D Trait-An Uncommon Haemoglobinopathy in Chattogram: A Case Report
*Correspondence to: Dr. Razia Sultana Professor Department of Laboratory Medicine Chottagram Maa-O-Shishu Hospital Medical College Chattogram, Bangladesh. Mobile : +88 01711 90 90 53 Email : razialucky24@gmail.com Abstract This case presents haemoglobin D Trait (Hb-D) which is a rare disease in Bangladesh. It is a heterozygous state for haemoglobin D who came to Laboratory Medicine Department of Chattogram Maa Shishu-O-General Hospital (CMSOGH) for heamoglobin electrophoresis. Our patient was 9 years old girl from Noakhali, Bangladesh. She was clinically silent with no splenomegaly. Her peripheral blood film was microcytic hypochromic anaemia and Capillary Electrophoresis (CE) of Hb revealed Hb D Trait. On family screening her father was Hb E trait, mother was Hb D trait and younger sister turned out normal Hb study. Compound heterozygosity for haemoglobin D and haemoglobin E may be present in subsequent pregnancy of her mother.
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