恶性皮肤肿瘤切除后鼻翼缺损即刻重建之研究

Mehmet Tapan, Ö. Özkan
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摘要

目的:国家综合癌症网络指南指出,任何患有鳞状或基底细胞皮肤癌的鼻区都是高危区。尽管莫氏手术是治疗多种皮肤癌的黄金标准,但它并不适用于全球。肿瘤患者的平均手术期为1.7 Mohs。鼻塞是莫氏手术的一个问题。在这项研究中,我们的目的是研究鼻翼区非黑色素瘤恶性皮肤肿瘤的立即重建切除,而不需要Mohs手术。方法:2018 - 2022年间,10例患者接受了重建手术。纳入标准为:鼻翼区直径小于1cm的溃疡性病变,皮镜检查怀疑为基底细胞癌(BCC)或鳞状细胞癌(SCC)的病变,鼻前镜检查时鼻黏膜完好的患者。结果:平均随访时间26个月。由于切除活检结果涉及边界邻近,没有患者需要再次手术。我们没有观察到严重的并发症和长期复发。结论:对于不适合Mohs手术的患者,我们推荐我们的算法。
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Immediate reconstruction of nasal alar defects after malignant skin tumor excision without mohs surgery
Objectives: The National Comprehensive Cancer Network guidelines state that any nasal region with squamous or basal cell skin cancer is at high risk. Although Mohs surgery is the gold-standard procedure for many types of skin cancer, it is not applicable worldwide. A mean of 1.7 Mohs surgery stage is performed in cases of tumors. Nasal obstruction is a problem with Mohs surgery. In this study, we aimed to investigate nasal alar region nonmelanoma malignant skin tumor excision using immediate reconstruction without Mohs surgery. Methods: Ten patients underwent reconstruction surgery between 2018 and 2022. The inclusion criterion were ulcerated lesions in the nasal alar region measuring less than 1 cm in diameter, the lesions which were suspected either as basal cell carcinoma (BCC) or squamous cell carcinoma (SCC) on dermatoscopic examination, the patients who had intact nasal mucosa during anterior rhinoscopy. Results: The mean follow-up duration was 26 months. No patient required re-operation because of an excisional biopsy result that involved border proximity. We observed no serious complications or long-term recurrences. Conclusion: We recommend our algorithm for patients for whom Mohs surgery is not applicable.
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