Ayşe Tüfekçi Balıkçı, Nurşah Demir, A. Burcu, Züleyha Yalnız Akkaya, E. Şingar, S. Uzman
Objective: To compare the outcomes of Descemet Membrane Endothelial Keratoplasty (DMEK) and Penetrating Keratoplasty (PK) in patients with pseudophakic bullous keratopathy (PBK). Methods: Records of 51 eyes of 51 PBK patients (32 male, 19 female) who underwent PK (Group1=38 eyes) and DMEK (Group 2=13 eyes) were reviewed retrospectively. The two groups were compared for Best-corrected visual acuity (BCVA), graft survival rates, and complications. Results: The mean age was 69.1 and 67.1 years in group 1 and group 2, respectively. First-year cumulative survival rates for group 1 and group 2 were 92.1% and 61.5%, respectively, and 89.1% and 51.3% in the second year (P=0.001 by log-rank test). At the last follow-up visit, 2.7% of Group 1 and 30.8% of Group 2 had a BCVA of 0.3 or better (P=0.004). Graft failure was observed in 12 eyes (31.6%) in group 1 and 8 eyes (61.5%) in group 2 (P=0.056). At the last examination, the rates of transparent grafts were 73.7% and 69.2% in group 1 and group 2, respectively (P=0.756). Postoperative glaucoma was observed in 4 eyes (30.8%) in the group 2 and 4 eyes (10.5%) in the group 1 (P=0.083). There was no significant difference between the two groups regarding other complications (P>0.05). Conclusions: DMEK surgery offers a better visual outcome than PK for the treatment of PBK. Careful follow-up of patients is required in terms of glaucoma and graft failure after DMEK. Although the graft survival rate was lower in the DMEK group, a similar rate of graft transparency was achieved at the final examination with repeated DMEK surgery.
{"title":"Descemet membrane endothelial keratoplasty and penetrating keratoplasty in pseudophakic bullous keratopathy: comparison of visual outcomes, graft survival rates, and complications","authors":"Ayşe Tüfekçi Balıkçı, Nurşah Demir, A. Burcu, Züleyha Yalnız Akkaya, E. Şingar, S. Uzman","doi":"10.18621/eurj.1449647","DOIUrl":"https://doi.org/10.18621/eurj.1449647","url":null,"abstract":"Objective: To compare the outcomes of Descemet Membrane Endothelial Keratoplasty (DMEK) and Penetrating Keratoplasty (PK) in patients with pseudophakic bullous keratopathy (PBK). \u0000Methods: Records of 51 eyes of 51 PBK patients (32 male, 19 female) who underwent PK (Group1=38 eyes) and DMEK (Group 2=13 eyes) were reviewed retrospectively. The two groups were compared for Best-corrected visual acuity (BCVA), graft survival rates, and complications. \u0000Results: The mean age was 69.1 and 67.1 years in group 1 and group 2, respectively. First-year cumulative survival rates for group 1 and group 2 were 92.1% and 61.5%, respectively, and 89.1% and 51.3% in the second year (P=0.001 by log-rank test). At the last follow-up visit, 2.7% of Group 1 and 30.8% of Group 2 had a BCVA of 0.3 or better (P=0.004). Graft failure was observed in 12 eyes (31.6%) in group 1 and 8 eyes (61.5%) in group 2 (P=0.056). At the last examination, the rates of transparent grafts were 73.7% and 69.2% in group 1 and group 2, respectively (P=0.756). Postoperative glaucoma was observed in 4 eyes (30.8%) in the group 2 and 4 eyes (10.5%) in the group 1 (P=0.083). There was no significant difference between the two groups regarding other complications (P>0.05). \u0000Conclusions: DMEK surgery offers a better visual outcome than PK for the treatment of PBK. Careful follow-up of patients is required in terms of glaucoma and graft failure after DMEK. Although the graft survival rate was lower in the DMEK group, a similar rate of graft transparency was achieved at the final examination with repeated DMEK surgery.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"18 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141113920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: Menopause, a biological milestone, marks a pivotal phase in women's lives characterized by ovarian function cessation and age-related changes. Our objective was to investigate menopausal symptoms and knowledge among women aged 40-60 years. Methods: This cross-sectional epidemiological study was conducted between June 1 and September 30, 2005, in the Nilufer Public Health Education and Research Area (NPHERA) region, aimed to assess menopausal symptoms and their correlates among 1013 women aged 40-60. The individuals included in the study were selected through a systematic sampling method, stratified by neighborhood weights and age groups based on the NPHERA 2004 Work Report and regional data, as well as information from the Health Centers Information System (HCIS), where the Electronic Health Records (EHR) are registered. Results: The mean age of natural menopause was found to be 46.7±4.8 years, showcasing sociodemographic factors' influence. Postmenopausal women experienced higher rates of symptoms, with physical and mental exhaustion (82.8%), irritability (78.4%), and depressive mood (76.4%) prevailing. Logistic regression revealed that employment status significantly influenced menopausal status. Moreover, the age at menopause correlated positively with the age of the woman's mother. Conclusion: This study contributes insights into menopausal experiences in developing countries, emphasizing the need for tailored healthcare approaches. Longitudinal investigations are warranted to comprehensively understand these associations and enhance women's quality of life during menopause.
{"title":"Exploring menopausal dynamics: a cross-sectional analysis of age, symptomatology, and sociodemographic influences in a developing population of women aged 40-60","authors":"Fatma Tuba Engindeniz, Anıl Erturk, Necla Aytekin","doi":"10.18621/eurj.1423025","DOIUrl":"https://doi.org/10.18621/eurj.1423025","url":null,"abstract":"Objectives: Menopause, a biological milestone, marks a pivotal phase in women's lives characterized by ovarian function cessation and age-related changes. Our objective was to investigate menopausal symptoms and knowledge among women aged 40-60 years. \u0000Methods: This cross-sectional epidemiological study was conducted between June 1 and September 30, 2005, in the Nilufer Public Health Education and Research Area (NPHERA) region, aimed to assess menopausal symptoms and their correlates among 1013 women aged 40-60. The individuals included in the study were selected through a systematic sampling method, stratified by neighborhood weights and age groups based on the NPHERA 2004 Work Report and regional data, as well as information from the Health Centers Information System (HCIS), where the Electronic Health Records (EHR) are registered. \u0000Results: The mean age of natural menopause was found to be 46.7±4.8 years, showcasing sociodemographic factors' influence. Postmenopausal women experienced higher rates of symptoms, with physical and mental exhaustion (82.8%), irritability (78.4%), and depressive mood (76.4%) prevailing. Logistic regression revealed that employment status significantly influenced menopausal status. Moreover, the age at menopause correlated positively with the age of the woman's mother. \u0000Conclusion: This study contributes insights into menopausal experiences in developing countries, emphasizing the need for tailored healthcare approaches. Longitudinal investigations are warranted to comprehensively understand these associations and enhance women's quality of life during menopause.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"120 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141115285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eisenmenger syndrome is characterized by the reversal of blood flow due to increased pulmonary vascular resistance. It can be prevented with early diagnosis and surgical treatment. Thromboembolism is a leading cause of death in patients with Eisenmenger syndrome. Pulmonary endarterectomy is the primary treatment, but medical treatments may be considered in inoperable cases. Regular follow-up and a multidisciplinary approach are important for diagnosis and treatment. Lifestyle changes and medical therapy can improve patient's quality of life and prevent complications. Our case is presented because of the chronic thromboembolic disease in addition to the pulmonary hypertension due to the partial atrioventricular septal defect and the management of the treatment.
{"title":"Eisenmenger syndrome presenting with chronic thromboembolic disease","authors":"A. Pazarlı, Kayıhan Karaman, Tuğba Yıldırım","doi":"10.18621/eurj.1440680","DOIUrl":"https://doi.org/10.18621/eurj.1440680","url":null,"abstract":"Eisenmenger syndrome is characterized by the reversal of blood flow due to increased pulmonary vascular resistance. It can be prevented with early diagnosis and surgical treatment. Thromboembolism is a leading cause of death in patients with Eisenmenger syndrome. Pulmonary endarterectomy is the primary treatment, but medical treatments may be considered in inoperable cases. Regular follow-up and a multidisciplinary approach are important for diagnosis and treatment. Lifestyle changes and medical therapy can improve patient's quality of life and prevent complications. Our case is presented because of the chronic thromboembolic disease in addition to the pulmonary hypertension due to the partial atrioventricular septal defect and the management of the treatment.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"137 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141115112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: Nurses have important responsibilities in providing effective pain management. This study was conducted to determine the level of knowledge and practices of rheumatology nurses regarding pain management. Methods: A descriptive study sample was 64 nurses in the rheumatology clinic. Data were collected using the Nurse Introduction Form and Questionnaire on Knowledge and Practices Regarding Pain Management. The data were evaluated in the SPSS. Results: It was determined that 73.4% of the rheumatology nurses did not receive training on pain management. The pain management knowledge score was moderate, and the knowledge of non-pharmacological pain management was insufficient. The mean pain management self-confidence score was 6.03±2.01 (0-10), and a positive correlation was found between the graduation year, working years in rheumatology, and pain management knowledge score (P
{"title":"Rheumatology nurses’ knowledge and practices on pain management","authors":"S. Pehlivan, Serap Özer","doi":"10.18621/eurj.1448013","DOIUrl":"https://doi.org/10.18621/eurj.1448013","url":null,"abstract":"Objective: Nurses have important responsibilities in providing effective pain management. This study was conducted to determine the level of knowledge and practices of rheumatology nurses regarding pain management. \u0000Methods: A descriptive study sample was 64 nurses in the rheumatology clinic. Data were collected using the Nurse Introduction Form and Questionnaire on Knowledge and Practices Regarding Pain Management. The data were evaluated in the SPSS. \u0000Results: It was determined that 73.4% of the rheumatology nurses did not receive training on pain management. The pain management knowledge score was moderate, and the knowledge of non-pharmacological pain management was insufficient. The mean pain management self-confidence score was 6.03±2.01 (0-10), and a positive correlation was found between the graduation year, working years in rheumatology, and pain management knowledge score (P","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"34 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141117089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: Fortilin is a multifunctional protein that protects cells against apoptosis. We aimed to investigate the levels of fortilin in patients with heart failure. Methods: Patients with ejection fraction (EF) below 40% were divided into two groups according to coronary angiography results: those with ischemic heart failure (Group 1) and those with non-ischemic heart failure (Group 2). Patients with normal anatomy and EF over 50% were included in the control group (Group 3). Results: A total of 119 patients were prospectively included in the study. A total of 81 patients (41 patients with ischemic heart failure and 40 patients with non-ischemic heart failure) were included in the heart failure group. 38 patients with EF >50 and normal coronary anatomy were included in the control group. There was no significant difference in serum fortilin levels between the study groups (Group 1: 5.5±2.6 ng/mL, Group 2: 6.1±3.8 ng/mL, and Group 3: 5.6±3.6 ng/mL; P=0.693). Fortilin did not show a correlation with any other variables. Conclusion: In our study, there was no significant difference in fortilin levels between the groups, and no relationship was found between coronary ischemia and fortilin levels in heart failure.
{"title":"Relationship between fortilin levels and coronary ischemia in heart failure","authors":"Sümeyra Gökçek, Cihan Aydın, Aykut Demirkıran, Şeref Alpsoy","doi":"10.18621/eurj.1447544","DOIUrl":"https://doi.org/10.18621/eurj.1447544","url":null,"abstract":"Objective: Fortilin is a multifunctional protein that protects cells against apoptosis. We aimed to investigate the levels of fortilin in patients with heart failure.\u0000Methods: Patients with ejection fraction (EF) below 40% were divided into two groups according to coronary angiography results: those with ischemic heart failure (Group 1) and those with non-ischemic heart failure (Group 2). Patients with normal anatomy and EF over 50% were included in the control group (Group 3).\u0000Results: A total of 119 patients were prospectively included in the study. A total of 81 patients (41 patients with ischemic heart failure and 40 patients with non-ischemic heart failure) were included in the heart failure group. 38 patients with EF >50 and normal coronary anatomy were included in the control group. There was no significant difference in serum fortilin levels between the study groups (Group 1: 5.5±2.6 ng/mL, Group 2: 6.1±3.8 ng/mL, and Group 3: 5.6±3.6 ng/mL; P=0.693). Fortilin did not show a correlation with any other variables.\u0000Conclusion: In our study, there was no significant difference in fortilin levels between the groups, and no relationship was found between coronary ischemia and fortilin levels in heart failure.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"110 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141125814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: The objective of this study is to determine the knowledge level and awareness of surgical nurses about fragile patients. Method: Obtained through Introductory Information Survey Form created by the researchers and Fragile Patient Information Evaluation Form methods. Results: The average age of the surgical nurses participating in the study was 28±5.01 years, the average professional experience was 5±5.09 years, and the average experience in the service they worked in was 3±2.83 years. The rate of those who heard the term 'frailty' for the first time is 63%. It was stated that 92.7% of the 110 surgical nurses participating in the study did not receive any training on fragility; It was stated that 50.9% of them think of the most vulnerable and weak patient when they think of a fragile patient. While 50% of them stated that when they suspected frailty in the patient, they evaluated involuntary weight loss, slowness (slowness in walking, muscle weakness), and fatigue; 70% stated that the biggest risk factor for frailty is being depressed or using antidepressant medication. Conclusions: According to the results of the study, it can be said that the awareness of surgical nurses about the "fragile patient" should be increased. In the light of the data obtained, it can be suggested to organize trainings on "fragile patients" for surgical nurses. 'Fragile patient' education should be included in pre-graduation education and in-service training.
{"title":"Determining the awareness of surgical nurses regarding frail patients: a cross-sectional study","authors":"İsmail Öztaş, A. Yava, Barıış Çeli̇k","doi":"10.18621/eurj.1398799","DOIUrl":"https://doi.org/10.18621/eurj.1398799","url":null,"abstract":"Objective: The objective of this study is to determine the knowledge level and awareness of surgical nurses about fragile patients.\u0000Method: Obtained through Introductory Information Survey Form created by the researchers and Fragile Patient Information Evaluation Form methods.\u0000Results: The average age of the surgical nurses participating in the study was 28±5.01 years, the average professional experience was 5±5.09 years, and the average experience in the service they worked in was 3±2.83 years. The rate of those who heard the term 'frailty' for the first time is 63%. It was stated that 92.7% of the 110 surgical nurses participating in the study did not receive any training on fragility; It was stated that 50.9% of them think of the most vulnerable and weak patient when they think of a fragile patient. While 50% of them stated that when they suspected frailty in the patient, they evaluated involuntary weight loss, slowness (slowness in walking, muscle weakness), and fatigue; 70% stated that the biggest risk factor for frailty is being depressed or using antidepressant medication.\u0000Conclusions: According to the results of the study, it can be said that the awareness of surgical nurses about the \"fragile patient\" should be increased. In the light of the data obtained, it can be suggested to organize trainings on \"fragile patients\" for surgical nurses. 'Fragile patient' education should be included in pre-graduation education and in-service training.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"21 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140225917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. G. Gür Özcan, Nezih Zengin, Burak Bi̇li̇r, Nurcan KAÇMAZ KAT, D. Durak
Objectives: The aim of this study is to investigate the hiatus defect diameter by measuring on multi-detector computed tomography images in hiatal hernia patients. Methods: The multi-detector computed tomography images of 50 patients and 50 individuals in control group included in this study were investigated. The hiatus surface area (cm²), hiatus antero-posterior and transverse diameters (cm), and the thickness of both diaphragmatic crura (mm) were measured by reformatting contrast-enhanced thoraco-abdomino-pelvic computed tomography images using the region of interest method. Results: In this study, a significant difference was obtained among groups according to hiatus surface area, hiatus antero-posterior, and transverse diameter measurements, and both left and right diaphragmatic crural thickness measurements (P<0.001). In the patient group, the cut-off values were determined by using ROC analysis, and the values above these cut-off values enabled a hernia diagnosis with high sensitivity and specificity. Conclusions: Measuring the hiatus surface area on multi-detector computed tomography images could serve as a supplementary criterion for diagnosing of hiatal hernia.
{"title":"Assessment of hiatus defect size in hiatal hernia patients using computed tomography","authors":"S. G. Gür Özcan, Nezih Zengin, Burak Bi̇li̇r, Nurcan KAÇMAZ KAT, D. Durak","doi":"10.18621/eurj.1392696","DOIUrl":"https://doi.org/10.18621/eurj.1392696","url":null,"abstract":"Objectives: The aim of this study is to investigate the hiatus defect diameter by measuring on multi-detector computed tomography images in hiatal hernia patients.\u0000Methods: The multi-detector computed tomography images of 50 patients and 50 individuals in control group included in this study were investigated. The hiatus surface area (cm²), hiatus antero-posterior and transverse diameters (cm), and the thickness of both diaphragmatic crura (mm) were measured by reformatting contrast-enhanced thoraco-abdomino-pelvic computed tomography images using the region of interest method.\u0000Results: In this study, a significant difference was obtained among groups according to hiatus surface area, hiatus antero-posterior, and transverse diameter measurements, and both left and right diaphragmatic crural thickness measurements (P<0.001). In the patient group, the cut-off values were determined by using ROC analysis, and the values above these cut-off values enabled a hernia diagnosis with high sensitivity and specificity.\u0000Conclusions: Measuring the hiatus surface area on multi-detector computed tomography images could serve as a supplementary criterion for diagnosing of hiatal hernia.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"79 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140232165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kubra Sahin Karadil, Ahmet Gülteki̇n, Ayhan Şahin, Sibel Özkan Gürdal, İ. Yildirim, C. Arar
Objectives: It was seen that recurrence and metastasis after breast cancer surgery are related to the immune response of the host. Anesthetic agents modulate the surgical stress response or directly impair the functions of immune system cells. In our study, we aimed to compare the effects of nonsteroidal anti-inflammatory drugs and erector spinae plane block, which are among the methods we use for postoperative analgesia, on the neutrophil/lymphocyte ratio and platelet/lymphocyte ratio in patients undergoing breast cancer surgery. Methods: One hundred female patients aged 18-75 years, scheduled for unilateral breast cancer surgery, and who agreed to participate were included in our study. These cases were divided into two groups of the analgesia method: Those with erector spinae plane block (Group E) and those who were administered nonsteroidal anti-inflammatory drugs (Group N). According to the results, preoperative and postoperative neutrophil/lymphocyte ratio and platelet/lymphocyte ratio values were calculated and recorded. Results: Neutrophil/lymphocyte ratio and platelet/lymphocyte ratio were statistically higher in both groups in the postoperative period. No statistically significant difference was found when the preoperative and postoperative measurement changes of the laboratory parameters between the groups were compared. Postoperative VAS scores were statistically significantly lower in Group E. Conclusions: We concluded that when erector spinae plane block and nonsteroidal anti-inflammatory drug use were compared in managing postoperative analgesia in breast cancer surgery, their effects on the neutrophil/lymphocyte ratio and platelet/lymphocyte ratio were not superior to each other. However, the erector spinae plane block was superior for adequate pain control.
{"title":"Comparison of the effect of erector spinae plane block for postoperative analgesia on neutrophil/lymphocyte ratio and platelet/lymphocyte ratio in patients operated for breast cancer","authors":"Kubra Sahin Karadil, Ahmet Gülteki̇n, Ayhan Şahin, Sibel Özkan Gürdal, İ. Yildirim, C. Arar","doi":"10.18621/eurj.1395544","DOIUrl":"https://doi.org/10.18621/eurj.1395544","url":null,"abstract":"Objectives: It was seen that recurrence and metastasis after breast cancer surgery are related to the immune response of the host. Anesthetic agents modulate the surgical stress response or directly impair the functions of immune system cells. In our study, we aimed to compare the effects of nonsteroidal anti-inflammatory drugs and erector spinae plane block, which are among the methods we use for postoperative analgesia, on the neutrophil/lymphocyte ratio and platelet/lymphocyte ratio in patients undergoing breast cancer surgery. \u0000Methods: One hundred female patients aged 18-75 years, scheduled for unilateral breast cancer surgery, and who agreed to participate were included in our study. These cases were divided into two groups of the analgesia method: Those with erector spinae plane block (Group E) and those who were administered nonsteroidal anti-inflammatory drugs (Group N). According to the results, preoperative and postoperative neutrophil/lymphocyte ratio and platelet/lymphocyte ratio values were calculated and recorded. \u0000Results: Neutrophil/lymphocyte ratio and platelet/lymphocyte ratio were statistically higher in both groups in the postoperative period. No statistically significant difference was found when the preoperative and postoperative measurement changes of the laboratory parameters between the groups were compared. Postoperative VAS scores were statistically significantly lower in Group E. \u0000Conclusions: We concluded that when erector spinae plane block and nonsteroidal anti-inflammatory drug use were compared in managing postoperative analgesia in breast cancer surgery, their effects on the neutrophil/lymphocyte ratio and platelet/lymphocyte ratio were not superior to each other. However, the erector spinae plane block was superior for adequate pain control.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"309 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140233166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nazlı Gamze Bülbül, S. Karşıdağ, N. Çınar, M. Ateş, Şevki Şahin, F. Karalı, Özge GÖNÜL ÖNER, T. Okluoğlu, F. Eren, Dilek Yilmaz Okuyan, Özlem Totuk, Meltem KARACAN GÖLEN, Esra ACIMAN DEMİREL, Z. Yıldırım, Hamdi Erhan, B. S. Arıca Polat, N. Ergin, E. Kobak Tur, Özlem Akdoğan
Objectives: Alzheimer’s disease (AH) is the most prevalent cause of dementia, followed closely by vascular dementia. Mixed vascular-Alzheimer’s dementia (MVAD) is more evident in individuals aged 80 and above. Frontotemporal dementia (FTD) is the second most common cause of early-onset dementia after AH. Vascular risk factors play important role in the pathogenesis of dementia syndromes. Behavioral and psychological symptoms represent a significant portion of the non-cognitive manifestations in dementia patients. This study aimed to evaluate the distribution of chronic diseases, behavioral disorders, psychiatric findings, and medication use in patients followed with different dementia diagnoses. Methods: Prevalance of chronic diseases, behavioral disorders, psychiatric findings as well as the usage of antidepressant and antipsychotic medications among patients followed up in dementia outpatient clinics with the diagnosis of AD, mild cognitive impairment (MCI), vascular dementia (VaD), FTD, and MVAD were investigated. Neuropsychiatric inventory (NPI) was applied to the patients. Results: Four hundred and fifty-five patients were accepted in the study. The patients were distributed as follows: AD (n=303, female/male: 187/115, age = 78±8 years), MCI (n=53, female/male: 31/22, age = 69±10 years), VaD (n=31, female/male: 18/13, age = 68±9 years), FTD (n=32, female/male: 17/15, age = 68±9 years), and MVAD (n=36, female/male: 16/20, age = 76±10 years). Both AD and MVAD groups were significantly older than the other groups (F = 23.2, P<0.0001). The ratio of comorbid chronic diseases was 80% in the AD group, 72% in the MCI group, 91% in the VaD group, 59% in the FTD group, and 93% in the MVAD group. In the whole group, antipsychotic drug use was 27.5% and antidepressant drug use was 28.9%. The mean NPI score was 32.9±28 in antipsychotic users and 16±19 in non-users (P<0.0001). The mean NPI of antidepressant users was 17.6±19 and 21.9±25 (P=0.055) in non-users. Conclusion: There is a comorbid chronic disease burden in all dementia subtypes, although at varying intensities, and as the chronic disease burden increases, behavioral disorders and psychotic findings increase, and accordingly, the use of antipsychotics also increases.
{"title":"Distribution of neuropsychiatric profiles and comorbid diseases in dementia subtypes","authors":"Nazlı Gamze Bülbül, S. Karşıdağ, N. Çınar, M. Ateş, Şevki Şahin, F. Karalı, Özge GÖNÜL ÖNER, T. Okluoğlu, F. Eren, Dilek Yilmaz Okuyan, Özlem Totuk, Meltem KARACAN GÖLEN, Esra ACIMAN DEMİREL, Z. Yıldırım, Hamdi Erhan, B. S. Arıca Polat, N. Ergin, E. Kobak Tur, Özlem Akdoğan","doi":"10.18621/eurj.1386582","DOIUrl":"https://doi.org/10.18621/eurj.1386582","url":null,"abstract":"Objectives: Alzheimer’s disease (AH) is the most prevalent cause of dementia, followed closely by vascular dementia. Mixed vascular-Alzheimer’s dementia (MVAD) is more evident in individuals aged 80 and above. Frontotemporal dementia (FTD) is the second most common cause of early-onset dementia after AH. Vascular risk factors play important role in the pathogenesis of dementia syndromes. Behavioral and psychological symptoms represent a significant portion of the non-cognitive manifestations in dementia patients. This study aimed to evaluate the distribution of chronic diseases, behavioral disorders, psychiatric findings, and medication use in patients followed with different dementia diagnoses.\u0000Methods: Prevalance of chronic diseases, behavioral disorders, psychiatric findings as well as the usage of antidepressant and antipsychotic medications among patients followed up in dementia outpatient clinics with the diagnosis of AD, mild cognitive impairment (MCI), vascular dementia (VaD), FTD, and MVAD were investigated. Neuropsychiatric inventory (NPI) was applied to the patients.\u0000Results: Four hundred and fifty-five patients were accepted in the study. The patients were distributed as follows: AD (n=303, female/male: 187/115, age = 78±8 years), MCI (n=53, female/male: 31/22, age = 69±10 years), VaD (n=31, female/male: 18/13, age = 68±9 years), FTD (n=32, female/male: 17/15, age = 68±9 years), and MVAD (n=36, female/male: 16/20, age = 76±10 years). Both AD and MVAD groups were significantly older than the other groups (F = 23.2, P<0.0001). The ratio of comorbid chronic diseases was 80% in the AD group, 72% in the MCI group, 91% in the VaD group, 59% in the FTD group, and 93% in the MVAD group. In the whole group, antipsychotic drug use was 27.5% and antidepressant drug use was 28.9%. The mean NPI score was 32.9±28 in antipsychotic users and 16±19 in non-users (P<0.0001). The mean NPI of antidepressant users was 17.6±19 and 21.9±25 (P=0.055) in non-users.\u0000Conclusion: There is a comorbid chronic disease burden in all dementia subtypes, although at varying intensities, and as the chronic disease burden increases, behavioral disorders and psychotic findings increase, and accordingly, the use of antipsychotics also increases.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"99 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140234069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Furkan Erdoğan, Tolgahan Cengiz, Alparslan Yurtbay, İ. Büyükceran
Objectives: Plantar fasciitis (PF), which accounts for approximately 80% of heel pain, is a common condition affecting adults' quality of life. There are many different treatment modalities used in the treatment of PF. In this study, we compared the clinical and functional outcomes of patients diagnosed with chronic PF in our clinic who underwent USG-guided PRP (platelet-rich plasma) injection and patients who underwent RFNA (radiofrequency nerve ablation) treatment. Methods: Ultrasound-guided PRP injection or RFNA was performed on 95 patients who were diagnosed with chronic PF and met the inclusion criteria. This group of patients was followed for at least one year (October 2021-October 2023), and the clinical and functional results of the patients were compared. Results: The mean pre-treatment Visual Analog Scale (VAS), Foot Function Index (FFI), and American Orthopaedic Foot and Ankle Society (AOFAS) posterior-ankle scores were similar, and no significant difference was found (P>0.05). A significant improvement was observed in the groups' FFI, VAS, and AFOAS scores after treatment (P<0.05). However, no significant difference was found in treatment modalities (P>0.05). Conclusions: As a result of the study, it was concluded that PRP injection and RFNA are effective treatment methods in patients diagnosed with chronic plantar fasciitis without response to other conservative treatment methods, but these two methods are not superior to each other.
{"title":"Ultrasound-guided platelet-rich plasma vs. radiofrequency nerve ablation for refractory plantar fasciitis","authors":"Furkan Erdoğan, Tolgahan Cengiz, Alparslan Yurtbay, İ. Büyükceran","doi":"10.18621/eurj.1388703","DOIUrl":"https://doi.org/10.18621/eurj.1388703","url":null,"abstract":"Objectives: Plantar fasciitis (PF), which accounts for approximately 80% of heel pain, is a common condition affecting adults' quality of life. There are many different treatment modalities used in the treatment of PF. In this study, we compared the clinical and functional outcomes of patients diagnosed with chronic PF in our clinic who underwent USG-guided PRP (platelet-rich plasma) injection and patients who underwent RFNA (radiofrequency nerve ablation) treatment. \u0000Methods: Ultrasound-guided PRP injection or RFNA was performed on 95 patients who were diagnosed with chronic PF and met the inclusion criteria. This group of patients was followed for at least one year (October 2021-October 2023), and the clinical and functional results of the patients were compared.\u0000Results: The mean pre-treatment Visual Analog Scale (VAS), Foot Function Index (FFI), and American Orthopaedic Foot and Ankle Society (AOFAS) posterior-ankle scores were similar, and no significant difference was found (P>0.05). A significant improvement was observed in the groups' FFI, VAS, and AFOAS scores after treatment (P<0.05). However, no significant difference was found in treatment modalities (P>0.05). \u0000Conclusions: As a result of the study, it was concluded that PRP injection and RFNA are effective treatment methods in patients diagnosed with chronic plantar fasciitis without response to other conservative treatment methods, but these two methods are not superior to each other.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"9 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140235289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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