哈萨克斯坦巴雷特食管的内镜治疗

K. Batyrbekov, A. Galiakbarova
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摘要

相关性:巴雷特食管(BE)是一种以食管扁平上皮化生为特征的特殊疾病。食管上皮上皮化生的主要危险是在病变部位发生恶性肿瘤的可能性很高——食管腺癌或心食道区癌。该研究旨在评估新的BE内窥镜治疗方法的临床有效性,以便随后在整个哈萨克斯坦共和国的广泛实践中实施。方法:本文报道2例Barrett食管不典型增生小于2.0 cm的患者临床应用氩等离子凝血治疗,3例Barrett食管不典型增生大于2.0 cm的患者应用环切治疗。结果:所有病例均显示应用治疗的有效性。对照形态学检查未见上皮BE的征象。结论:本文描述了在我们诊所引入内窥镜BE治疗方法的结果,并可在整个哈萨克斯坦广泛实施。广泛采用内窥镜治疗癌前病变将减少哈萨克斯坦人口食管癌的发病率
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ENDOSCOPIC TREATMENT OF BARRETT’S ESOPHAGUS IN KAZAKHSTAN
Relevance: Barrett’s esophagus (BE) is a special disease characterized by metaplasia of the flat epithelium of the esophagus. The main danger of esophageal epithelial metaplasia is the high probability of develop-ing a malignant neoplasm at the site of the lesion – esophageal adenocarcinoma or can-cer of the cardioesophageal zone. The study aimed to evaluate the clinical effectiveness of new BE endoscopic treat-ment methods for their subsequent implementation in wide practice throughout the Re-public of Kazakhstan. Methods: This article presents cases of clinical use of argon plasma coagulation of dysplasia lesions less than 2.0 cm in two patients with Barrett’s esophagus and the use of loop resection of dysplasia lesions more than 2.0 cm in three patients with Barrett’s esophagus. Results: All the presented cases have shown the effectiveness of applied treatment. Control morphological examination showed no signs of BE in the epithelium. Conclusion: The presented article describes the results of the introduction of endo-scopic BE treatment methods in our clinic and is available for wide implementation throughout Kazakhstan. A widespread introduction of endoscopic treatment of precan-cerous pathology will reduce the incidence of esophageal cancer in the Kazakhstani population
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