硫代三唑啉对社区获得性肺炎患者细胞和体液免疫状态的影响

V. I. Vishnevskij, I. I. Mironenko, O. Demyanenko
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引用次数: 0

摘要

对149例社区获得性肺炎患者,观察抗氧化剂噻三唑啉对细胞免疫和体液免疫状态的影响。研究表明院外肺炎是在继发性免疫缺陷的背景下发生的,表现为循环t淋巴细胞总量及其亚群的减少:nk细胞、t辅助细胞、t抑制细胞、Ig a和Ig G增加而Ig M减少。噻三唑啉在社区获得性肺炎患者的综合治疗中伴随着总t淋巴细胞减少及其亚群的减少,其背景是Ig M类免疫球蛋白含量的增加,Ig a和Ig g类免疫球蛋白的减少。在社区获得性肺炎患者的细胞和体液免疫变化的背景下,使用噻三唑啉进行疗程治疗
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The effect of thiotriazoline on the state of cellular and humoral immunity in patients with community-acquired pneumonia
149 patients with community-acquired pneumonia, the influence of the antioxidant tiotriazoline on the state of cellular and humoral immunity was studied. Studies have shown that out-of-hospital pneumonia occurs against the background of secondary immunodeficiency, which is manifested by a decrease in the total circulating T-lymphocytes and their subpopulations: NK-cells, T-helper cells, T-suppressors, Ig A and Ig G increase in Ig M decrease. Tiotriazoline in the complex therapy of patients with community-acquired pneumonia is accompanied by a decrease in both total T-lymphocytopenia and their subpopulations against the background of an increase in the content of immunoglobulins of class Ig M reduction in immunoglobulin classes Ig A and Ig G. of changes in cellular and humoral immunity in patients with community-acquired against the background of course treatment with thiotriazoline
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