学龄前儿童健康监测是发现关键身体异常的有效手段吗?

Dr Cliona Ni Bhrolchain
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摘要

方法:本研究是一项前瞻性研究,对诺丁汉25%的全科医生注册的母亲所生的1年队列儿童进行研究。对2308名婴儿进行了15-18个月的随访。通过医院记录系统和儿童个人健康记录的儿童健康监测审查副本,对所有因五种示踪性身体状况(睾丸隐睾、先天性心脏病、斜视、髋关节发育不良和先天性听力损失)转诊的患者进行随访。结果随访1272例(85%)。413名(21%)儿童因其中一种示踪条件而转诊,91%的儿童直接从儿童健康监测审查中转诊。只有49名(12%)儿童在评估后需要治疗或随访。筛查的灵敏度很高,从先天性心脏病的72%到髋关节发育不良和听力损失的100%。然而,假阳性率也很高,从睾丸隐睾的60%到髋关节发育不良和听力损失的97%不等。因此,髋部发育不良或听力损失转诊的阳性预测值仅为5%,阴性预测值为100%。相比之下,隐睾阳性预测值为67%,假阴性率为14%。在评估后需要治疗或随访的儿童中,有84%是从儿童健康监测方案转介过来的。在6周的复查中发现了最大比例的异常,但大多数转诊来自新生儿复查和健康访问者分心测试。结论本研究中使用的五种示踪条件的大多数儿童是在儿童健康监测检查中发现的。
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Is preschool child health surveillance an effective means of detecting key physical abnormalities?

Method This was a prospective study of a 1-year cohort of children born to mothers registered with 25% of general practices in Nottingham. A cohort of 2308 babies was followed up for 15–18 months. All referrals for five tracer physical conditions (undescended testes, congenital heart disease, squints, developmental dysplasia of the hip and congenital hearing loss) were followed up through hospital record systems and copies of child health surveillance reviews from the personal child health records.

Results One thousand, nine hundred and seventy-two (85%) of the initial cohort were followed up. Four hundred and thirteen (21%) children had been referred for one of the tracer conditions and 91% had been referred directly from child health surveillance reviews. Only 49 (12%) children needed treatment or follow-up after assessment. The sensitivity of screening was high, ranging from 72% for congenital heart disease to 100% for developmental dysplasia of the hip and hearing loss. However, false positive rates were also very high, ranging from 60% for undescended testes to 97% for developmental dysplasia of the hip and hearing loss. Thus the positive predictive value of referral for dysplasia of the hip or hearing loss was only 5%, with a negative predictive value of 100%. In contrast, the positive predictive value for undescended testes was 67%, with a false negative rate of 14%. Eighty-four per cent of those who needed treatment or follow-up after assessment had been referred from the child health surveillance programme. The largest proportion of abnormalities was identified from the 6-week review, but most referrals came from the neonatal review and the health visitor distraction test.

Conclusion The majority of children with the five tracer conditions used in this study were identified during child health surveillance examinations.

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