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The greatest impact of war and conflict 战争和冲突的最大影响
Pub Date : 2009-10-12 DOI: 10.1046/j.1467-0658.2001.0115b.x
Anna Maria Mandalakas
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引用次数: 0
Social gradients in child health: why do they occur and what can paediatricians do about them? 儿童健康中的社会梯度:为什么会发生,儿科医生能做些什么?
Pub Date : 2009-08-12 DOI: 10.1046/j.1467-0658.2000.00086-2.x
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引用次数: 0
Current literature 目前的文献
Pub Date : 2009-08-12 DOI: 10.1046/j.1467-0658.2000.00081-2.x
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引用次数: 0
Child, adolescent and student health monitor 儿童、青少年和学生健康监督员
Pub Date : 2009-08-12 DOI: 10.1046/j.1467-0658.2000.00093.x
Dr Ashok Nathwani
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引用次数: 0
Improving compliance with tuberculin skin test interpretation in children 提高儿童结核菌素皮肤试验解释的依从性
Pub Date : 2009-08-06 DOI: 10.1046/j.1467-0658.2000.00031.x
Julie A Boom, Connie Hughes, Teneille Brown, Richard M Rutstein

Objective  To evaluate the effect of a quality improvement initiative which utilized educational interventions combined with a phone follow-up program on the rate of return for tuberculin skin test (TST) interpretation.

Design Before and after trial with analysis of practice records for all TSTs placed.

Setting/Sample  The study was conducted in a resident and attending primary care practice in an urban children's hospital. All children (n = 1315) who had TSTs placed during August and October of 1995 and August and October of 1996 were included in the study.

Intervention  Medical staff were re-educated regarding TST screening. Patients families were given written information about tuberculosis. Physicians and nursing staff discussed TST screening with the patients' families prior to TST placement. All patients received a series of three reminder telephone calls on three consecutive days to remind them to return for TST interpretation followed by a letter if necessary. The following data were collected: date of birth, age, zip code, type of provider, transit time from the hospital, type of health insurance, number of telephone calls made, and return status for TST interpretation. Return rates were compared pre- and post-intervention.

Results  A total of 1315 TSTs were placed during the pre- (n = 611) and post-(n = 704) intervention periods. Return rates increased from 6.2 to 61.5%. Attendings' patients and those with private insurance were more likely to return. There was no relationship to season, age or distance from the practice.

Conclusions  Targeted screening programs utilizing more effective methods for TST interpretation should be considered.

目的评价采用教育干预与电话随访相结合的质量改进方案对结核菌素皮肤试验(TST)解释成功率的影响。设计试验前后,分析所有测试的实践记录。背景/样本本研究是在一所城市儿童医院的住院医师和主治初级保健实践中进行的。所有在1995年8月和10月以及1996年8月和10月接受测试的儿童(n = 1315)被纳入研究。对医务人员进行了关于TST筛查的再教育。向病人家属提供有关结核病的书面信息。医生和护理人员在TST安置前与患者家属讨论了TST筛查。所有患者连续三天接到三次提醒电话,提醒他们返回进行TST口译,必要时还会收到一封信。收集了以下数据:出生日期、年龄、邮政编码、提供者类型、从医院到医院的中转时间、健康保险类型、拨打的电话数量以及返回TST口译的状态。比较干预前和干预后的回报率。结果干预前(n = 611)和干预后(n = 704)共放置tst 1315张。回报率从6.2上升到61.5%。主治医生的病人和那些有私人保险的病人更有可能回来。这与季节、年龄或距离无关。结论应考虑采用更有效的TST解释方法进行有针对性的筛查。
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引用次数: 0
The changing utilization of a children’s emergency department 儿童急诊科使用率的变化
Pub Date : 2009-08-06 DOI: 10.1046/j.1467-0658.2000.00055.x
Robert Boyle, Craig Smith, John McIntyre

Objective To assess the changing pattern of attendance at an emergency department in a children’s hospital.

Design A retrospective review of the attendance register from 1 September 1986 to 31 August 1998.

Setting Derbyshire Children’s Hospital, Derby, serving a mixed urban and rural population within the National Health Service.

Measurement Total number of attendances and admissions each year. For one week in February and August each year: age and case mix assessed. For the period 1994–98: the source of the referral and the outcome of patients referred by their General Practitioner (GP).

Results Over the study period: a rise in attendances from 4853 to 8796; no change in the total number admitted to hospital. A decline in the proportion admitted from 56 to 32%. For the period 1994–98: no change in the number of patients referred by their GP; an increasing number of self-referrals. Overall age mix: age < 1 year, 27%; age 1–4 years, 42%; age 5–12 years, 26%; age > 13 years, 5%. Overall case mix: medical, 73%; surgical, 9%; trauma/minor injuries, 18%.

Conclusion An important change has occurred in the utilization of our paediatric emergency department with increasing numbers of children seeking hospital assessment, largely via self-referrals, but not requiring hospital admission.

Implications for practice Future planning and deployment of paediatric resources need to take account of the change in use of hospital emergency services.

目的了解某儿童医院急诊科就诊情况的变化。设计回顾1986年9月1日至1998年8月31日的考勤记录。在德比郡设立德比郡儿童医院,在国家卫生服务体系内为城乡混合人口提供服务。每年的总出席人数和入学人数。每年2月和8月的一周:评估年龄和病例组合。1994 - 1998年期间:由全科医生转诊的病人的转诊来源和转诊结果。在研究期间,出勤人数从4853人增加到8796人;入院总人数没有变化。录取率从56%下降到32%。1994 - 1998年期间:由全科医生转诊的病人人数没有变化;越来越多的自我推荐。整体年龄组合:年龄<1年,27%;1-4岁,42%;5-12岁,26%;年龄比;13年,5%总体病例组合:医疗,73%;手术,9%;创伤/轻伤,18%。结论儿科急诊科的使用率发生了重要变化,越来越多的儿童寻求医院评估,主要是通过自我转诊,但不需要住院。对实践的影响未来儿科资源的规划和部署需要考虑到医院急诊服务使用的变化。
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引用次数: 9
Oral versus initial intravenous therapy for urinary tract infections in young febrile children. 早期发热儿童尿路感染的口服与初始静脉治疗。
Pub Date : 2009-08-06 DOI: 10.1046/j.1467-0658.2000.0062h.x
Robert M Jacobson MD

Background The standard recommendation for treatment of young, febrile children with urinary tract infection has been hospitalization for intravenous antimicrobials. The availability of potent, oral, third-generation cephalosporins, as well as interest in cost containment and avoidance of nosocomial risks prompted evaluation of the safety and efficacy of outpatient therapy.

Methods In a multicentre, randomized clinical trial, the investigators evaluated the efficacy of oral versus initial intravenous therapy in 306 children 1 to 24 months old with fever and urinary tract infection, in terms of short-term clinical outcomes (sterilization of the urine and defervescence) and long-term morbidity (incidence of reinfection and incidence and extent of renal scarring documented at 6 months by 99mTc-dimercaptosuccinic acid renal scans). Children received either oral cefixime for 14 days (double dose on day 1) or initial intravenous cefotaxime for 3 days followed by oral cefixime for 11 days. Costs were estimated using charge-data.

Results Treatment groups were comparable regarding demographic, clinical, and laboratory characteristics. Of the short-term outcomes: (1) repeat urine cultures were sterile within 24 h in all 306 children, and (2) mean time to defervescence was 25 and 24 h for children treated orally and intravenously, respectively. Of the long-term outcomes: (1) symptomatic re-infections occurred in 4.6% of children treated orally and 7.2% of children treated intravenously; (2) renal scarring at 6 months was noted in 9.8% of children treated orally versus 7.2% of children treated intravenously; and (3) mean extent of scarring was ~8% in both treatment groups. Mean costs were at least twofold higher for children treated intravenously ($3577 versus $1473) compared with those treated orally.

Conclusions Oral cefixime can be recommended as a safe and effective treatment for children with fever and urinary tract infection. Use of cefixime will result in substantial reductions of health care expenditures.

背景:治疗年幼发热儿童尿路感染的标准建议是住院静脉注射抗菌素。有效的口服第三代头孢菌素的可用性,以及对成本控制和避免医院风险的兴趣,促使对门诊治疗的安全性和有效性进行评估。方法在一项多中心随机临床试验中,研究人员评估了306名1至24个月大的发热和尿路感染儿童口服与初始静脉治疗的疗效,包括短期临床结果(尿消毒和退热)和长期发病率(6个月时99mtc -二巯丁二酸肾脏扫描记录的再感染发生率和肾瘢痕的发生率和程度)。儿童口服头孢克肟14天(第1天双倍剂量)或初始静脉注射头孢克肟3天,随后口服头孢克肟11天。成本是根据电荷数据估算的。结果治疗组在人口学、临床和实验室特征方面具有可比性。短期结果:(1)所有306名儿童的重复尿培养在24小时内无菌,(2)口服和静脉注射儿童的平均退热时间分别为25和24小时。长期结果:(1)有症状的再感染发生率为口服治疗儿童的4.6%,静脉注射治疗儿童的7.2%;(2) 6个月时,9.8%的口服治疗儿童出现肾脏瘢痕,而7.2%的静脉注射治疗儿童出现肾脏瘢痕;(3)两组平均瘢痕形成程度为~8%。与口服治疗相比,静脉治疗儿童的平均费用至少高出两倍(3577美元对1473美元)。结论口服头孢克肟是一种安全有效的治疗小儿发热和尿路感染的方法。使用头孢克肟将大大减少卫生保健支出。
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引用次数: 51
A randomised trial of three marketing strategies to disseminate a screening and brief alcohol intervention programme to general practitioners. 三种营销策略的随机试验,向全科医生传播筛查和简短的酒精干预方案。
Pub Date : 2009-08-06 DOI: 10.1046/j.1467-0658.2000.0062b.x
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引用次数: 35
Advising parents of asthmatic children on passive smoking: randomised controlled trial. 建议哮喘儿童家长不要被动吸烟:随机对照试验。
Pub Date : 2009-08-06 DOI: 10.1046/j.1467-0658.2000.0062g.x
Richard Reading

Objective A randomised controlled trial to investigate whether parents of asthmatic children would stop smoking or alter their smoking habits to protect their children from environmental tobacco smoke.

Participants 501 families with an asthmatic child aged 2–12 years living with a parent who smoked.

Intervention Parents were told about the impact of passive smoking on asthma and advised to stop or change their smoking habits to protect their child’s health.

Main outcome measures Salivary cotinine concentrations in children, and changes in reported smoking habits of the parents 1 year after the intervention.

Results One year after the baseline visit, a small decrease in salivary cotinine concentrations was found in both groups of children, but there was no significant difference between the groups. Overall, 98% of parents in both groups still smoked at follow-up. However, there was a nonsignificant tendency for parents in the intervention group to report smoking more at follow-up and to having a reduced desire to stop smoking.

Conclusions A brief intervention to advise parents of asthmatic children about the risks from passive smoking was ineffective in reducing their children’s exposure to environmental tobacco smoke. If a clinician believes that a child’s health is being affected by parental smoking, the parent’s smoking needs to be addressed as a separate issue from the child’s health.

目的通过一项随机对照试验,探讨哮喘患儿家长是否愿意戒烟或改变吸烟习惯,以保护孩子免受环境烟草烟雾的危害。参与者是501个有2-12岁哮喘儿童且父母吸烟的家庭。家长们被告知被动吸烟对哮喘的影响,并被建议停止或改变吸烟习惯,以保护孩子的健康。主要结果测量儿童唾液中可替宁浓度,以及干预后1年父母吸烟习惯的变化。结果基线访视一年后,两组儿童唾液可替宁浓度均有小幅下降,但两组间无显著差异。总体而言,两组中98%的父母在随访时仍在吸烟。然而,干预组的父母在随访中报告吸烟更多,并且戒烟意愿降低的趋势并不明显。结论对哮喘儿童家长进行被动吸烟危害的简短干预对减少儿童环境烟草烟雾暴露效果不显著。如果临床医生认为孩子的健康受到父母吸烟的影响,父母吸烟需要作为一个独立的问题与孩子的健康分开来处理。
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引用次数: 13
A study of the efficacy of antipyretic drugs in the prevention of febrile seizure recurrence 解热药物预防热性惊厥复发的疗效研究
Pub Date : 2009-08-06 DOI: 10.1046/j.1467-0658.2000.00059.x
Adrianus van Esch, Ewout W Steyerberg, Henriëtte A Moll, Martin Offringa, Arne W Hoes, J Dik F Habbema, Gerdarda Derksen-Lubsen

Objective To estimate the potential preventive effect of antipyretic drugs on the recurrence of febrile seizures (FS).

Design An experimental and a descriptive patient series, both prospectively followed, were combined in this study.

Setting/participants Children who visited the outpatient department of the Sophia Children’s Hospital because of a FS experienced between the age of 10 and 36 months.

Intervention A treatment group of 109 children was offered treatment with ibuprofen or acetaminophen syrup during fever, a control group of 103 children was not offered antipyretic treatment. This was not a randomized trial. In an intention-to-treat analysis, the risk of any recurrence and the number of recurrences per fever were compared between both groups. In an additional on-treatment analysis, we compared the number of recurrences per fever between the control group and the children in the treatment group who actually received the study medication during fever. Effect measures were odds ratio (OR) as estimated by the Mantel–Haenszel procedure and hazard ratios (HR) as estimated by Cox regression.

Results According to the intention-to-treat analysis, the hazard ratio of any recurrence in the treatment group compared with the control group was 1.1 [95% confidence interval (CI), 0.7–1.8]. The recurrence risk per fever was 15% in the treatment group and 12% in the control group (OR, 1.2; 95% CI, 0.7–2.3). In the exploratory on-treatment analysis, the recurrence risk in the treatment group was estimated 6.9% in the treatment group versus 12% in the control group (OR, 0.5; 95% CI, 0.2–1.3).

Conclusions/implications for practice We conclude that antipyretic treatment may have little or no preventive effect on the recurrence of febrile seizures in common practice. Some reduction of the risk of a recurrence may be acquired under optimal circumstances, namely that fever is noticed at once and that antipyretic drugs can be administered on time.

目的探讨退热药物对热性惊厥(FS)复发的潜在预防作用。设计本研究结合了前瞻性随访的实验性和描述性患者系列。背景/参与者在索菲亚儿童医院门诊部就诊的年龄在10至36个月之间的儿童。干预治疗组109例患儿在发热时给予布洛芬或对乙酰氨基酚糖浆治疗,对照组103例患儿不给予退烧药治疗。这不是一个随机试验。在意向治疗分析中,比较两组之间任何复发的风险和每次发烧的复发次数。在另一项治疗分析中,我们比较了对照组和治疗组在发烧期间实际接受研究药物治疗的儿童每次发烧的复发率。效果测量是通过Mantel-Haenszel程序估计的优势比(OR)和Cox回归估计的风险比(HR)。结果意向治疗分析显示,治疗组与对照组相比,任何复发的风险比为1.1[95%可信区间(CI), 0.7 ~ 1.8]。治疗组每次发热的复发风险为15%,对照组为12% (OR, 1.2;95% ci, 0.7-2.3)。在探索性治疗分析中,治疗组的复发风险估计为6.9%,而对照组为12% (OR, 0.5;95% ci, 0.2-1.3)。结论/实践意义我们的结论是,在常见的实践中,退热治疗对热性惊厥的复发可能只有很少或没有预防作用。在最佳情况下,即立即发现发热,及时给予退烧药,可使复发的危险有所降低。
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引用次数: 23
期刊
Ambulatory Child Health
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