Assessment of Quality of Life of Hepatitis C Patients Treated By Sovaldi Drug in Viral Hepatitis Treatment Center in Ismailia Fever Hospital, Egypt

Introduction: patients with chronic liver disease are suffering from fatigue, loss of self-esteem, inability to function at work, anxiety, depression, and other emotional problems that profoundly decrease their quality of life and well-being. Objectives: To assess the quality of life of hepatitis C patients receiving Sovaldi drug. To determine most common short-term side effects of Sovaldi containing regimen medication. Methods: A descriptive cross sectional study was carried out in Viral Hepatitis Treatment Center Ismailia fever Hospital. Study population was Hepatitis c virus patients treated with regimen containing sovaldi (sovaldi+ribavirin for 12 weeks). Simple random sampling was used to select the subjects included in the study Using sample size ready-made tables, 74 patients were selected to participate in this study where an interviewing questionnaire used to collect the data by 36 RAND questionnaire. Results: About 49% of the patients noticed change in their mode to the worst, and 5% felt depressed to the extent of suicide and about 61% of the patients were having difficulty with sleeping and concentrating. About half of the patients (50%) were having poor role-emotional. the most common short-term side effect were Headache which was the highest (53%) while others as(joint pain-decreasing sexual function-decreasing appetite) followed it. 35.2% were having excellent social functioning during the period of treatment of sovaldi, whereas (about 56.8%) ranging from poor to fair social functioning. Conclusion: the study was carried on 74 patients and the results were controversial as regarding their lifestyle affection, some people got better and others got worse especially those experienced recurrence of the disease. We recommend larger studies with large sample size to detect effectively the life style changes with medication.