冠状动脉正常的2型心肌梗死1例报告并文献复习

Afm Azim Anwar, Sanjida Anjum Mumu, Azharul Islam, Md Fakhrul Islam Khaled, Khurshed Ahmed, Md. Harisul Hoque
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摘要

临床医生早就认识到急性心肌梗死(MI)可以发生在没有动脉粥样硬化血栓形成。心肌梗死全球通用定义工作组于2007年引入了一个分类系统(并于2012年重申),将2型心肌梗死(遵循标准诊断标准)定义为由于心肌氧供应和/或需求失衡而发生的心肌梗死,而不是由动脉粥样硬化斑块破坏引起的。然而,关于如何诊断2型心肌梗死以及如何将其与1型心肌梗死和心肌损伤区分开来,仍然存在歧义。在此,我们报告一例23岁的年轻女性在急诊室就诊,典型的胸痛和呼吸短促6小时,腹泻2天,单次意识丧失5分钟,入院前6小时。心肌酶在随后的样品中呈上升趋势,血清肌酐也很高。36小时后超声心动图未见局部壁运动异常,冠状动脉造影显示冠状动脉正常。因此,我们诊断为心肌梗死(2型MI)伴非阻塞性冠状动脉(MINOCA), MINOCA归因于低血容量性休克(由Dirrrahoea引起),表现为MI、晕厥和AKI。大学心脏杂志2022;18 (2): 128 - 131
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A Case of Type 2 MI with Normal Coronary Arteries: Case Report & Literature Review
Clinicians have long recognized that acute myocardial infarction (MI) can occur in the absence of atherothrombosis . The Universal Definition of MI Global Taskforce introduced a classification system in 2007 (and reaffirmed in 2012) that defined type 2 MI (following standard diagnostic criteria) as MI occurring due to an imbalance in myocardial oxygen supply and/or demand not caused by atherosclerotic plaque disruption. Nevertheless, ambiguity remains regarding how to diagnose type 2 MI and how to distinguish it from both type 1 MI and myocardial injury. Here we report a case of a 23 year old young woman attended to emergency department, with typical chest pain and shortness of breath for 6 hours, Diarrhoea for 2 days, and single time loss of consciousness for 5 minutes, 6 hours before attending to hospital. Cardiac enzymes were rising titres in subsequent samples, Serum Creatinine was also high. Echocardiography performed 36 hour later, showed no regional wall motion abnormality, coronary angiogram showed normal coronary arteries. So, a diagnosis of Myocardial Infarction (Type 2 MI) with Non Obstructive Coronary Artery (MINOCA) was made, and MINOCA was attributed to hypovolemic shock (resulting from Dirrrahoea), manifested as MI, Syncope and AKI. University Heart Journal 2022; 18(2): 128-131
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