用于伤口敷料的PVA和PVP水凝胶混合物:合成和表征

M. Mureșan-Pop, K. Magyari, A. Vulpoi
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引用次数: 8

摘要

本研究的目的是开发和表征新型聚乙烯醇(PVA)/聚乙烯醇(PVP)水凝胶共混物。通过x射线衍射(XRD)、差热分析(DTA/TGA)和傅里叶变换红外光谱(FTIR)进一步表征了两种聚合物溶液的不同混合物,得到了几种水凝胶。通过观察和比较干燥和在蒸馏水中再水化后的样品,研究了聚合物类型对水凝胶水化的影响。结果表明,再水化后水凝胶的无定形特性保持不变,软化分解温度升高与PVA含量的增加有直接关系。PVA含量最高的水凝胶在pH值为6时润湿膨胀效果最好。
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PVA and PVP Hydrogel Blends for Wound Dressing: Synthesis and Characterisation
The purpose of this study is the development and characterizations of novel polyvinyl alcohol (PVA)/polyvinyl pyrolidone (PVP) hydrogel blends. Different mixtures of the two polymeric solutions leaded to several hydrogels that were further characterized using X-ray difraction (XRD), differential thermal and thermogravimetric analysis (DTA/TGA) and Fourier transform infrared spectroscopy (FTIR). The influence of the polymer type on hydrogel hydration was also studied, by observing and comparing the samples after drying and rehydration in bidistilled water. The results revealed the maintenance of the amorphous character of the hydrogels after rehydration as well as a higher softening and decomposition temperature in direct relation with the increase of PVA content. The best wetting and swelling results were also given by the hydrogel with the highest PVA content prepared at pH 6.
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