K. Jatczak, Mariusz M. Gruza, Katarzyna Filip, P. Cmoch, G. Grynkiewicz
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Preparation of selectively protected protoescigenin derivatives for synthesis of escin analogs and neoglycoconjugates
Protoescigenin, the main aglycone of horse chestnut saponin mixture known as escin, was selected as substrate for exploratory chemistry towards selective protection, followed by propargyl ether formation and subsequent condensation with azido-monosaccharides, to obtain novel triazole linked conjugates of the triterpene.
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