登革热:儿科患者的临床、实验室概况和结果

Pooja Gandhi, Pinkal Taral, K. Patel, Sanketsinh Rathod, Bhavini Rathwa
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摘要

4种登革热病毒血清型中的任何一种感染都会导致一系列不同的症状,从轻度未分化热到危及生命的出血热和休克。鉴于登革热病毒感染引起如此广泛的临床症状,早期和准确的实验室诊断对于适当的患者管理至关重要。因此进行了一项研究来了解它的临床特征,实验室特征与登革热的严重程度和登革热患者的结果之间的相关性。目的:探讨三级医疗中心登革热患者的临床特征、实验室特征与登革热严重程度及转归的相关性。方法:2019年5月1日至2021年4月31日进行回顾性观察研究。结果:在2019年5月1日至2021年4月31日期间,共研究了323例患者。最常见的临床表现是发热(100%),最常见的临床表现是肝肿大(14.2%)。所有重症登革热感染者血小板计数均< 50000/cumm。323例登革热患者194例(60%),DHF 1级85例(26.4%),DHF 2级出院9例(2.8%),DSS患者死亡13例(4%)。22例(6.8%)行DAMA。结论:登革热流行区可通过出现恶心、呕吐、腹痛、肝肿大等临床指标对登革热进行可靠诊断。监测血小板计数、红细胞压积和白细胞计数对登革热病例的管理非常有用。关键词:登革热,血小板计数,结局
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Dengue Fever: Clinical, Laboratory Profile and Outcome in Pediatric Patient
Introduction: Infection with any of the 4 dengue virus serotypes results in a diverse range of symptoms, from mild undifferentiated fever to life-threatening hemorrhagic fever and shock. Given that dengue virus infection elicits such a broad range of clinical symptoms, early and accurate laboratory diagnosis is essential for appropriate patient management. So a study was carried out to know its clinical profile, correlation between the laboratory profile and the severity of dengue fever and outcome in dengue patients. Aim: To study the clinical profile, correlation between the laboratory profile and the severity of dengue fever and outcome in dengue patients at tertiary care center. Method: Retrospective Observational study from 1st May 2019 to 31st April 2021. Result: Total 323 patients were studied during 1st May 2019 to 31st April 2021. Most common presentation was fever (100%), most common clinical finding is hepatomegaly (14.2%). All severe dengue infection has platelet count < 50000/cumm. In study of 323 patients 194(60%) of dengue fever,85(26.4%) of DHF GRADE 1,9(2.8%) of DHF GRADE 2 were discharged .13(4%) patients of DSS were expired.22 patients (6.8%) went DAMA. Conclusion: Reliable diagnosis of dengue fever in endemic areas can be done by clinical parameters like presence of nausea, vomiting, pain abdomen and hepatomegaly. Monitoring platelet count, hematocrit and WBC count is very useful for management of dengue cases. Keywords: dengue fever, platelet count, outcome
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