Pub Date : 2024-07-27DOI: 10.32553/ijmsdr.v8i3.1031
Arnabjyoti De
Manipur, located in northeastern India, has faced intermittent episodes of violence over the years. However, the latest surge in conflict has uniquely strained its healthcare system. Hospitals and clinics have been damaged, leading to the interruption of routine medical services and the depletion of essential supplies. Health workers, facing threats to their safety, have often been unable to perform their duties, resulting in a shortage of medical professionals in critical areas. The violence has led to population displacement, creating new healthcare challenges. Internally displaced persons (IDPs) have congregated in camps with limited access to clean water, sanitation, and medical care, increasing the risk of disease outbreaks. This situation has placed additional pressure on an already fragile healthcare system, struggling to meet the needs of both the displaced population and the broader community. Keywords: Humanit arian-crisis, Manipur-conflict, ethic-conflict, Kuki-Meitei conflict, Healthcare crisis
{"title":"The Curtain of Blood: Understanding Humanitarian and Healthcare Crisis in Manipur","authors":"Arnabjyoti De","doi":"10.32553/ijmsdr.v8i3.1031","DOIUrl":"https://doi.org/10.32553/ijmsdr.v8i3.1031","url":null,"abstract":"Manipur, located in northeastern India, has faced intermittent episodes of violence over the years. However, the latest surge in conflict has uniquely strained its healthcare system. Hospitals and clinics have been damaged, leading to the interruption of routine medical services and the depletion of essential supplies. Health workers, facing threats to their safety, have often been unable to perform their duties, resulting in a shortage of medical professionals in critical areas. The violence has led to population displacement, creating new healthcare challenges. Internally displaced persons (IDPs) have congregated in camps with limited access to clean water, sanitation, and medical care, increasing the risk of disease outbreaks. This situation has placed additional pressure on an already fragile healthcare system, struggling to meet the needs of both the displaced population and the broader community. \u0000Keywords: Humanit arian-crisis, Manipur-conflict, ethic-conflict, Kuki-Meitei conflict, Healthcare crisis","PeriodicalId":14075,"journal":{"name":"International Journal of Medical Science And Diagnosis Research","volume":"1 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141798114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-02DOI: 10.32553/ijmsdr.v8i2.1023
Mohammad S N
Use of intravenous (IV) tissue plasminogen(tPA) as a fibrinolytic therapy for acute ischemic stroke is a standard acute phase treatment. The common complication of tPA is hemorrhage, especially intracranial. But there are other rare sites of bleeding. We present one such rare case of a patient developing spontaneous hemopericardium after IV tPA for acute ischemic stroke. Keywords: coagulopathy, hemopericardium, Ischemic stroke, tissue plasminogen activator
{"title":"Spontaneous Hemopericardium Post-Thrombolysis in Stroke","authors":"Mohammad S N","doi":"10.32553/ijmsdr.v8i2.1023","DOIUrl":"https://doi.org/10.32553/ijmsdr.v8i2.1023","url":null,"abstract":"Use of intravenous (IV) tissue plasminogen(tPA) as a fibrinolytic therapy for acute ischemic stroke is a standard acute phase treatment. The common complication of tPA is hemorrhage, especially intracranial. But there are other rare sites of bleeding. We present one such rare case of a patient developing spontaneous hemopericardium after IV tPA for acute ischemic stroke.\u0000Keywords: coagulopathy, hemopericardium, Ischemic stroke, tissue plasminogen activator","PeriodicalId":14075,"journal":{"name":"International Journal of Medical Science And Diagnosis Research","volume":"52 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141273860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-17DOI: 10.32553/ijmsdr.v8i1.1019
Eslam K Fahmy, Safya E. Esmaeel
Background: Mesenchymal stem cells (MSCs) are among the most frequently used cell type for regenerative medicine and have beneficial effects to treat different pathologies, including neurological disorders, cardiac ischemia, diabetes, and bone and cartilage diseases, Fortunately, MSCs, known for their lower immunogenicity and self-renewal ability, can be induced into insulin-producing cells (IPCs) and have attracted significant attention for the treatment of DM. Importantly.
{"title":"Mesenchymal Stem Cells Ameliorate Lipid Metabolism while Reducing Blood Glucose in Streptozotocin (STZ)-Induced Diabetes Mellitus and High Fat Diet Induced Obesity","authors":"Eslam K Fahmy, Safya E. Esmaeel","doi":"10.32553/ijmsdr.v8i1.1019","DOIUrl":"https://doi.org/10.32553/ijmsdr.v8i1.1019","url":null,"abstract":"Background: Mesenchymal stem cells (MSCs) are among the most frequently used cell type for regenerative medicine and have beneficial effects to treat different pathologies, including neurological disorders, cardiac ischemia, diabetes, and bone and cartilage diseases, Fortunately, MSCs, known for their lower immunogenicity and self-renewal ability, can be induced into insulin-producing cells (IPCs) and have attracted significant attention for the treatment of DM. Importantly. \u0000 ","PeriodicalId":14075,"journal":{"name":"International Journal of Medical Science And Diagnosis Research","volume":"135 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140693552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-17DOI: 10.32553/ijmsdr.v8i1.1020
Safya E. Esmaeel, Anshoo Agarwal
The mean values of insulin and glucose and HOMA IR were significant decreases in HFD/obese metformin, and gold nanoparticles treated
胰岛素、血糖和 HOMA IR 的平均值在高密度脂蛋白胆固醇/肥胖二甲双胍和金纳米颗粒治疗中显著下降。
{"title":"Metformin Therapy Assisted by Nanotechnology as a Possible Combinational Treatment for Diabetes Mellitus an Experimental Study","authors":"Safya E. Esmaeel, Anshoo Agarwal","doi":"10.32553/ijmsdr.v8i1.1020","DOIUrl":"https://doi.org/10.32553/ijmsdr.v8i1.1020","url":null,"abstract":"The mean values of insulin and glucose and HOMA IR were significant decreases in HFD/obese metformin, and gold nanoparticles treated","PeriodicalId":14075,"journal":{"name":"International Journal of Medical Science And Diagnosis Research","volume":" 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140691318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-28DOI: 10.32553/ijmsdr.v8i1.1010
A. Dar, M. Nabi, Ubaid Jeelani, Aadil Najeed
Aims and Objectives: The aim of this study was to determine the epidemiological parameters, including age and sex distribution, clinical presentation, tumour classification and role of radiation therapy in the management of head and neck Paragangliomas. Materials and Methods: This was a retrospective study of 15 patients treated for head and neck Paragangliomas in the Department of Radiation Oncology Government Medical College, Srinagar between January 2021 and April 2023. Results: The median age of the study participants was 50 years, ranging from 26 to 70. Among the patients, there were 10 females and 5 males, resulting in a sex ratio of 2:1. Tinnitus was the most frequent symptom, observed in 64% of cases, followed by Vertigo (28%), Headache (21%), and hearing loss (21%). 86.7% of Paragangliomas were benign while 13.3% were malignant. All patients (15 patients) underwent radiation therapy, which was used exclusively in 12 (80%) patients and as an additional treatment following surgical resection in 3 (20%) patients. The median radiation dose administered was 50Gy, with a range of 25-54, and it was delivered through Image Guided Radiotherapy (VMAT and IMRT). There were no severe treatment related complications. After a median follow-up period of 18 months, ranging from 6 to 28, all patients achieved local control, defined as radiological stability or regression, and there were no reported deaths. Conclusion: In conclusion, this study demonstrated the effectiveness of radiation therapy in managing a diverse group of patients with varying symptoms. Most patients achieved local control with minimal complications during 18-month follow-up, underscoring the treatment's success. Keywords: Paraganglioma, Head and Neck, Radiotherapy.
{"title":"Exploring Radiation Therapy for Head and Neck Paragangliomas: Insights from a Tertiary Care Hospital","authors":"A. Dar, M. Nabi, Ubaid Jeelani, Aadil Najeed","doi":"10.32553/ijmsdr.v8i1.1010","DOIUrl":"https://doi.org/10.32553/ijmsdr.v8i1.1010","url":null,"abstract":"Aims and Objectives: The aim of this study was to determine the epidemiological parameters, including age and sex distribution, clinical presentation, tumour classification and role of radiation therapy in the management of head and neck Paragangliomas.\u0000Materials and Methods: This was a retrospective study of 15 patients treated for head and neck Paragangliomas in the Department of Radiation Oncology Government Medical College, Srinagar between January 2021 and April 2023.\u0000Results: The median age of the study participants was 50 years, ranging from 26 to 70. Among the patients, there were 10 females and 5 males, resulting in a sex ratio of 2:1. Tinnitus was the most frequent symptom, observed in 64% of cases, followed by Vertigo (28%), Headache (21%), and hearing loss (21%). 86.7% of Paragangliomas were benign while 13.3% were malignant. All patients (15 patients) underwent radiation therapy, which was used exclusively in 12 (80%) patients and as an additional treatment following surgical resection in 3 (20%) patients. The median radiation dose administered was 50Gy, with a range of 25-54, and it was delivered through Image Guided Radiotherapy (VMAT and IMRT). There were no severe treatment related complications. After a median follow-up period of 18 months, ranging from 6 to 28, all patients achieved local control, defined as radiological stability or regression, and there were no reported deaths.\u0000Conclusion: In conclusion, this study demonstrated the effectiveness of radiation therapy in managing a diverse group of patients with varying symptoms. Most patients achieved local control with minimal complications during 18-month follow-up, underscoring the treatment's success.\u0000Keywords: Paraganglioma, Head and Neck, Radiotherapy.","PeriodicalId":14075,"journal":{"name":"International Journal of Medical Science And Diagnosis Research","volume":"95 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140370833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-06DOI: 10.32553/ijmsdr.v8i1.1005
Anil Mohan Rao. S, Anshoo Aggarwal
Blood Transfusion is one of the most important, Potent and Critical therapeutic tools in the realm of Clinical Management of Patients. Modern Blood banking involves carefully coordinated sophisticated and integrated teamwork comprising of well experienced Technicians, Physicians along with the Donor/Patient support. It consists of latest Machinery and infrastructure to cater to the needs of patients, along with regular internal / external Audit, quality control and Calibration of Machines, which is vital to the efficient functioning of Blood Bank and delivery of smooth, accurate results. The aim of this study is to explore the various latest aspects of Blood Banking and reinforce the knowledge of Medical Community
{"title":"Recent Trends and Practices in Blood Transfusion","authors":"Anil Mohan Rao. S, Anshoo Aggarwal","doi":"10.32553/ijmsdr.v8i1.1005","DOIUrl":"https://doi.org/10.32553/ijmsdr.v8i1.1005","url":null,"abstract":"Blood Transfusion is one of the most important, Potent and Critical therapeutic tools in the realm of Clinical Management of Patients. Modern Blood banking involves carefully coordinated sophisticated and integrated teamwork comprising of well experienced Technicians, Physicians along with the Donor/Patient support. It consists of latest Machinery and infrastructure to cater to the needs of patients, along with regular internal / external Audit, quality control and Calibration of Machines, which is vital to the efficient functioning of Blood Bank and delivery of smooth, accurate results. The aim of this study is to explore the various latest aspects of Blood Banking and reinforce the knowledge of Medical Community","PeriodicalId":14075,"journal":{"name":"International Journal of Medical Science And Diagnosis Research","volume":"24 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140261103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Carpal tunnel syndrome (CTS) is an entrapment neuropathy in which median nerve is compressed or squeezed at the wrist level in the carpal tunnel. Carpal tunnel syndrome is the most prevalent neurological complication in the rheumatoid arthritis patients. The prevalence of CTS in RA ranged from 3.5% to 22.8 %. Tenosynovitis, inflammation of the synovial tissue of the flexor tendons, can cause increased pressure in the carpal tunnel and result in CTS. Hand function is usually affected in carpel tunnel syndrome which affects the daily living performance by affecting both gross motor activities like grasping, carrying, holding and fine motor activities like writing, gripping and buttoning the shirts. Laser therapy, also called as photo biomodulation, can reduce pain, inflammation, swelling and synovitis. The dexterity and functionality of the hands improved through hand and wrist stretching and strengthening exercises. Objective: To find out the effect of laser therapy, neurodynamic mobilization exercises and strengthening exercises on hand function in patients of carpal tunnel syndrome with rheumatoid arthritis. Study selection: This narrative review is conducted on databases from Pubmed, Google scholar, scopus, web of knowledge, Virtual Health Library, Research Gate and Cochrane library in Nov 2023.
背景：腕管综合征（CTS）是一种正中神经在腕管内受压或受挤压的卡压性神经病。腕管综合征是类风湿性关节炎患者最常见的神经并发症。腕管综合征在类风湿性关节炎患者中的发病率为 3.5% 至 22.8%。腱鞘炎（屈肌腱滑膜组织的炎症）可导致腕管压力增加，从而引发 CTS。腕管综合症患者的手部功能通常会受到影响，从而影响抓、提、握等粗大运动和写字、抓握、扣衬衫扣子等精细运动，从而影响日常生活能力。激光疗法又称光生物调节疗法，可减轻疼痛、炎症、肿胀和滑膜炎。通过手部和腕部的伸展和强化训练，手部的灵活性和功能得到改善。研究目的了解激光疗法、神经动力调动练习和强化练习对类风湿性关节炎腕管综合征患者手部功能的影响。研究选择：本叙述性综述于 2023 年 11 月在 Pubmed、Google scholar、scopus、web of knowledge、Virtual Health Library、Research Gate 和 Cochrane library 等数据库中进行检索。
{"title":"Effect of Laser Therapy, Neurodynamic Stabilization and Strengthening Exercises on Hand Function in Patients of Carpal Tunnel Syndrome with Rheumatoid Arthritis- A Narrative Review","authors":"Zafar Mohammad, Dimple Choudhry, Anubha Garg, Anshu Kumari, Vikas Singh","doi":"10.32553/ijmsdr.v7i6.1003","DOIUrl":"https://doi.org/10.32553/ijmsdr.v7i6.1003","url":null,"abstract":"Background: Carpal tunnel syndrome (CTS) is an entrapment neuropathy in which median nerve is compressed or squeezed at the wrist level in the carpal tunnel. Carpal tunnel syndrome is the most prevalent neurological complication in the rheumatoid arthritis patients. The prevalence of CTS in RA ranged from 3.5% to 22.8 %. Tenosynovitis, inflammation of the synovial tissue of the flexor tendons, can cause increased pressure in the carpal tunnel and result in CTS. Hand function is usually affected in carpel tunnel syndrome which affects the daily living performance by affecting both gross motor activities like grasping, carrying, holding and fine motor activities like writing, gripping and buttoning the shirts. Laser therapy, also called as photo biomodulation, can reduce pain, inflammation, swelling and synovitis. The dexterity and functionality of the hands improved through hand and wrist stretching and strengthening exercises. \u0000Objective: To find out the effect of laser therapy, neurodynamic mobilization exercises and strengthening exercises on hand function in patients of carpal tunnel syndrome with rheumatoid arthritis. \u0000Study selection: This narrative review is conducted on databases from Pubmed, Google scholar, scopus, web of knowledge, Virtual Health Library, Research Gate and Cochrane library in Nov 2023.","PeriodicalId":14075,"journal":{"name":"International Journal of Medical Science And Diagnosis Research","volume":"40 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139846045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Carpal tunnel syndrome (CTS) is an entrapment neuropathy in which median nerve is compressed or squeezed at the wrist level in the carpal tunnel. Carpal tunnel syndrome is the most prevalent neurological complication in the rheumatoid arthritis patients. The prevalence of CTS in RA ranged from 3.5% to 22.8 %. Tenosynovitis, inflammation of the synovial tissue of the flexor tendons, can cause increased pressure in the carpal tunnel and result in CTS. Hand function is usually affected in carpel tunnel syndrome which affects the daily living performance by affecting both gross motor activities like grasping, carrying, holding and fine motor activities like writing, gripping and buttoning the shirts. Laser therapy, also called as photo biomodulation, can reduce pain, inflammation, swelling and synovitis. The dexterity and functionality of the hands improved through hand and wrist stretching and strengthening exercises. Objective: To find out the effect of laser therapy, neurodynamic mobilization exercises and strengthening exercises on hand function in patients of carpal tunnel syndrome with rheumatoid arthritis. Study selection: This narrative review is conducted on databases from Pubmed, Google scholar, scopus, web of knowledge, Virtual Health Library, Research Gate and Cochrane library in Nov 2023.
背景：腕管综合征（CTS）是一种正中神经在腕管内受压或受挤压的卡压性神经病。腕管综合征是类风湿性关节炎患者最常见的神经并发症。腕管综合征在类风湿性关节炎患者中的发病率为 3.5% 至 22.8%。腱鞘炎（屈肌腱滑膜组织的炎症）可导致腕管压力增加，从而引发 CTS。腕管综合症患者的手部功能通常会受到影响，从而影响抓、提、握等粗大运动和写字、抓握、扣衬衫扣子等精细运动，从而影响日常生活能力。激光疗法又称光生物调节疗法，可减轻疼痛、炎症、肿胀和滑膜炎。通过手部和腕部的伸展和强化训练，手部的灵活性和功能得到改善。研究目的了解激光疗法、神经动力调动练习和强化练习对类风湿性关节炎腕管综合征患者手部功能的影响。研究选择：本叙述性综述于 2023 年 11 月在 Pubmed、Google scholar、scopus、web of knowledge、Virtual Health Library、Research Gate 和 Cochrane library 等数据库中进行检索。
{"title":"Effect of Laser Therapy, Neurodynamic Stabilization and Strengthening Exercises on Hand Function in Patients of Carpal Tunnel Syndrome with Rheumatoid Arthritis- A Narrative Review","authors":"Zafar Mohammad, Dimple Choudhry, Anubha Garg, Anshu Kumari, Vikas Singh","doi":"10.32553/ijmsdr.v7i6.1003","DOIUrl":"https://doi.org/10.32553/ijmsdr.v7i6.1003","url":null,"abstract":"Background: Carpal tunnel syndrome (CTS) is an entrapment neuropathy in which median nerve is compressed or squeezed at the wrist level in the carpal tunnel. Carpal tunnel syndrome is the most prevalent neurological complication in the rheumatoid arthritis patients. The prevalence of CTS in RA ranged from 3.5% to 22.8 %. Tenosynovitis, inflammation of the synovial tissue of the flexor tendons, can cause increased pressure in the carpal tunnel and result in CTS. Hand function is usually affected in carpel tunnel syndrome which affects the daily living performance by affecting both gross motor activities like grasping, carrying, holding and fine motor activities like writing, gripping and buttoning the shirts. Laser therapy, also called as photo biomodulation, can reduce pain, inflammation, swelling and synovitis. The dexterity and functionality of the hands improved through hand and wrist stretching and strengthening exercises. \u0000Objective: To find out the effect of laser therapy, neurodynamic mobilization exercises and strengthening exercises on hand function in patients of carpal tunnel syndrome with rheumatoid arthritis. \u0000Study selection: This narrative review is conducted on databases from Pubmed, Google scholar, scopus, web of knowledge, Virtual Health Library, Research Gate and Cochrane library in Nov 2023.","PeriodicalId":14075,"journal":{"name":"International Journal of Medical Science And Diagnosis Research","volume":"104 49","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139786183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-30DOI: 10.32553/ijmsdr.v7i5.995
Sangeeta Sharma, Naresh Sharma
Introduction: Iron deficiency anaemia (IDA) is the most common nutritional deficiency in pregnancy. Anemia results in poor pregnancy outcome and also affects fetal outcome. This study was undertaken to evaluate the response of intravenous iron given to pregnant women with severe IDA and their feto-maternal outcome.
Methodology: A prospective study was conducted in the department of Obstetrics & Gynaecology, at a tertiary care centre of Northern India. Fifty-two pregnant women with haemoglobin between 5-7 g% with diagnosed iron deficiency attending antenatal clinic were given intravenous iron complex Follow-up after 4 weeks was done and IDA specific blood profile was done at baseline and at follow-up. Feto-maternal outcomes were seen at delivery.
Results: The mean age of study population was 25.5 ± 3.96 yrs. Improvement at 4 week follow-up from baseline in hemoglobin (p value-0.001) and iron profiles (S. Iron, Total Iron Binding Capacity (TIBC), S. Ferritin) (p value -0.0001) were highly significant. On comparing the Hb levels at delivery after intravenous infusion at 28-34 weeks gestation, 17 patients were still below 8 gm%, whereas 35 were above 8 gm%. Distribution of IUGR, preterm labor and blood transfusion in postpartum period were statistically significant amongst both group (p value<0.05). Fetal outcomes were also evaluated amongst the 2 groups. Distribution of Preterm birth, birth weight and NICU admission was also statistically significant (p value<0.05).
Conclusion: The intravascular iron therapy definitely has a rapid increase in haemoglobin which can prevent the complications due to severe anaemia in pregnancy and blood transfusion can also be prevented, but iron stores are not replenished to the optimum level, so there is a need to give replacement therapy (by oral route) post transfusion for long term benefits. The rise of hemoglobin affects feto-maternal outcomes even in the last trimester.contrast agents. This is a first case report of AHCM portrayed by this ingenious technology.
Keywords: AMCH, IUGR, TIBC
{"title":"Intravenous Iron Therapy in Severe Anemia at 28-34 Weeks of Gestation and it’s Feto-Maternal Outcome- A Prospective Study from A Developing Country","authors":"Sangeeta Sharma, Naresh Sharma","doi":"10.32553/ijmsdr.v7i5.995","DOIUrl":"https://doi.org/10.32553/ijmsdr.v7i5.995","url":null,"abstract":"Introduction: Iron deficiency anaemia (IDA) is the most common nutritional deficiency in pregnancy. Anemia results in poor pregnancy outcome and also affects fetal outcome. This study was undertaken to evaluate the response of intravenous iron given to pregnant women with severe IDA and their feto-maternal outcome.
 Methodology: A prospective study was conducted in the department of Obstetrics & Gynaecology, at a tertiary care centre of Northern India. Fifty-two pregnant women with haemoglobin between 5-7 g% with diagnosed iron deficiency attending antenatal clinic were given intravenous iron complex Follow-up after 4 weeks was done and IDA specific blood profile was done at baseline and at follow-up. Feto-maternal outcomes were seen at delivery.
 Results: The mean age of study population was 25.5 ± 3.96 yrs. Improvement at 4 week follow-up from baseline in hemoglobin (p value-0.001) and iron profiles (S. Iron, Total Iron Binding Capacity (TIBC), S. Ferritin) (p value -0.0001) were highly significant. On comparing the Hb levels at delivery after intravenous infusion at 28-34 weeks gestation, 17 patients were still below 8 gm%, whereas 35 were above 8 gm%. Distribution of IUGR, preterm labor and blood transfusion in postpartum period were statistically significant amongst both group (p value<0.05). Fetal outcomes were also evaluated amongst the 2 groups. Distribution of Preterm birth, birth weight and NICU admission was also statistically significant (p value<0.05).
 Conclusion: The intravascular iron therapy definitely has a rapid increase in haemoglobin which can prevent the complications due to severe anaemia in pregnancy and blood transfusion can also be prevented, but iron stores are not replenished to the optimum level, so there is a need to give replacement therapy (by oral route) post transfusion for long term benefits. The rise of hemoglobin affects feto-maternal outcomes even in the last trimester.contrast agents. This is a first case report of AHCM portrayed by this ingenious technology.
 Keywords: AMCH, IUGR, TIBC","PeriodicalId":14075,"journal":{"name":"International Journal of Medical Science And Diagnosis Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136102550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-30DOI: 10.32553/ijmsdr.v7i5.996
Akhil Mehrotra, Sajid Ansari, Mohammed Shaban, Shubham Kacker
Hypertrophic cardiomyopathy (HCM) is a relatively common inherited cardiomyopathy, which is occasionally challenging to differentiate from hypertensive heart disease and athletes heart on the basis of morphologic or functional abnormalities alone. Imaging studies provide solution for majority of clinical presentations. Generally, transthoracic echocardiography (TTE) is employed as a first line imaging tool and contrast enhanced echocardiography (CEE), contrast tuned imaging echocardiography (CTIE), cardiac magnetic resonance (CMR), cardiac computed tomography (CCT), cardiac nuclear imaging and speckle tracking echocardiography (STE) are encouraged for either suboptimal studies because of poor visualization of left ventricular (LV) cavity or for comprehensive delineation of the cardiac anatomy, its widespread left and right ventricular involvement, associations and complications. We are reporting a case of 48-year old male presenting to us with atypical chest pain and a history of suspicious solitary episode of syncope. His routine ECG was indicative of left ventricular hypertrophy with strain pattern, and his TTE was substandard and inadequate in the apical four chamber (4CH) and five chamber (5CH) views, hence CTIE was performed without the application of intravenous contrast agents, to produce a remarkable illustration of HCM.
Keywords: Hypertrophic cardiomyopathy, contrast echocardiography, contrast tuned imaging, speckle tracking echocardiography, 4Dimensional XStrain, Non obstructive HCM
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 Keywords: Hypertrophic cardiomyopathy, contrast echocardiography, contrast tuned imaging, speckle tracking echocardiography, 4Dimensional XStrain, Non obstructive HCM","PeriodicalId":14075,"journal":{"name":"International Journal of Medical Science And Diagnosis Research","volume":"22 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136104284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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