RuCl3·nH2O催化非对映选择性直接醛醇反应:生成激素类固醇衍生物的有效途径

K. Tabatabaeian, E. Keshavarz, M. Mamaghani, N. Mahmoodi
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引用次数: 3

摘要

ruiii催化孕酮与芳香醛的区域选择性和非对映选择性直接醛醇反应,收率为58 ~ 78%。该方法的优点是催化效率高,反应时间短,易于操作和维修。
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RuCl3 · nH2O as Catalyst for Diastereoselective Direct Aldol Reaction: An Efficient Route to Hormone Steroid Derivatives
RuIII-catalyzed regio- and diastereoselective direct aldol reaction of progesterone with aromatic aldehydes has been developed in good yields (58–78%). Advantages of this method include catalytic efficiency, short reaction times, and ease of operation and workup.
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