纳米颗粒作为有前途的替代抗菌剂的评价

O. Zherebyateva, L. Aznabaeva, Diana Galimovna Ukubaeva, E. A. Mikhailova, Alexandr S. Pankov, O. Bolshakova, S. Sarantseva, V. Lebedev, Andrey Yuryevich Mironov
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引用次数: 0

摘要

寻找能够抑制微生物生长的新物质是相关的。因此,本文评价了碳纳米颗粒对人为环境物体表面微生物分离株生长和生物膜形成的影响。已经证实,C60 + PVP + AC960钻石平台上的碳纳米颗粒能够抑制革兰氏阳性和革兰氏阴性原核生物以及假丝酵母属真菌和曲霉属真菌的生长、繁殖和生物膜形成能力。在C60+AC960富勒烯的影响下,表皮葡萄球菌、蜡样芽孢杆菌、大肠杆菌和白色念珠菌的生物膜生成能力被显著抑制。这些数据为进一步研究这些化合物作为一种有前景的抗菌剂提供了基础。关键词:抗菌作用,纳米碳,生物膜形成,富勒烯,纳米金刚石。
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Evaluation of nanoparticles as promising alternative antimicrobials
The search for new substances capable of inhibiting the growth of microorganisms is relevant. Therefore, an assessment was made of the effect of carbon nanoparticles on the growth and biofilm formation of microbial isolates from the surfaces of anthropogenic environmental objects. It has been established that carbon nanoparticles on the C60 + PVP + AC960 diamond platform are able to suppress the growth, reproduction and ability to biofilm formation of gram-positive and gram-negative prokaryotes, as well as fungi of the genus Candida and Aspergillus. Under the influence of C60+AC960 fullerenes, the biofilm-generation ability of Staphylococcus epidermidis, Bacillus cereus, Escherichia coli, and Candida albicans was significantly inhibited. These data provide a basis for further study of these compounds as a promising antimicrobial agent. Keywords: Antimicrobial action, carbon nanoparticles, biofilm formation, fullerenes, nanodiamonds.
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