高效连续流动混合的微观结构

F. G. Bessoth, A. deMello, A. Manz
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引用次数: 370

摘要

本文提出了一种基于流动分层原理的层流流态微混合器。该结构由玻璃/硅/玻璃夹层组成,总内部体积≡600nl,尺寸为5mm × 10mm。流速在1-200µL min-1之间已成功使用。荧光猝灭实验进行定量,15 ms内混合率为95%。
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Microstructure for efficient continuous flow mixing
This paper presents a micromixer for the laminar flow regime based on the principle of flow lamination. The structure is made up from a glass/silicon/glass sandwich, has a total internal volume of ≡600 nL and measures 5 mm × 10 mm. Flow rates between 1–200 µL min–1 have successfully been used. Fluorescence quenching experiments were carried out for quantification and showed 95% mixing within 15 ms.
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