ABO血型是否与呼吸异常易感性有关?尼日利亚河流州土著大学生的对照横断面研究

J. N. Asiwe, E. Umoren, T. Kolawole, K. B. Etim, Adedolapo Adeola Agbeluyi, Nicholas Asiwe, V. Igbokwe
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摘要

背景:血型是一种遗传定义的免疫系统特征,在移植和化疗中具有众所周知的作用。然而,尚不清楚它在诊断或预测呼吸系统疾病方面的作用。本研究旨在调查ABO血型人群呼吸系统疾病的患病率。本研究调查了ABO血型间呼吸系统疾病的患病率。方法:采用定量调查研究设计,对来自河流州不同地方政府辖区的102名17-28岁的年轻大学生(女64名,男36名)进行横断面研究。采用半结构化问卷收集被调查者的社会人口学特征。进行了人体测量和呼吸功能测试。结果:A型、B型、O型、AB型的患病率分别为19.6%、16.7%、56.9%、6.9%。体重指数显示,体重不足、正常、超重和肥胖分别为2.9%、39.2%、38.2%和19.6%。呼吸系统疾病在不同血型之间的分布不均匀,阻塞性肺功能障碍的发生频率最高。结论:呼吸异常易感性与任何血型无关,O型血发生阻塞性肺疾病的风险较高,主要受优势型的影响。
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Does ABO Blood Type Implicate Susceptibility to Respiratory Abnormalities? A Controlled Cross-sectional Study among Indigenous University Students in Rivers State, Nigeria
Background: The blood typing is a genetically defined immune system characteristic that has a well-known role in transplantation and chemotherapy. However, it is unclear what role it could serve in diagnosing or predicting respiratory pathologies. The study aims at investigating the prevalence of respiratory disorder among ABO blood type. This study investigated the prevalence of respiratory disorder among ABO blood types. Methods: Using a quantitative survey research design, this cross-sectional study comprises of 102 young University students (64 females and 36 males) within the age of 17-28 years, extracted from different local Government Area in Rivers State. A semi-structured questionnaire was used to gather the social demograpgic characteristics of respondent’s. Anthropometric investigations and respiratory function test was done. Results: The prevalent blood types A, B, O, and AB was 19.6%, 16.7%, 56.9%, and 6.9% respectively. BMI showed that 2.9%, 39.2%, 38.2% and 19.6% was underweight, normal weight, overweight and obese respectively. Respiratory problems were distributed unevenly among blood types, with risk of obstructive pulmonary dysfunction having the highest frequency of occurrence. Conclusion: The susceptibility to respiratory abnormalities is not associated with any blood type, the risk of obstructive pulmonary disease is higher in blood type O, which is largely influenced by the predominancy.
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