{"title":"现场演示:微型植入物的感应电源和遥测技术","authors":"P. Häfliger","doi":"10.1109/ISCAS.2010.5537016","DOIUrl":null,"url":null,"abstract":"A prototype for a wireless implantable sensor system is demonstrated intended for a pill sized micro-implant for blood sugar monitoring. Power is sent and telemetry data received over a near field inductive link. The implant system is almost completely realized on a single CMOS ASIC, excepting three surface mounted capacitors, the coil antenna and the sensor. For this demonstration, the ASIC is packaged and mounted with the 4 other components on a PCB, and the glucose sensor is substituted with either a potentiometer or an atmospheric pressure sensor. In the targeted highly miniaturized implantable micro system all components (including antenna and sensor) will be integrated into a pill sized LTCC (low temperature cofired ceramics) package. The total implant power budget with the minimal supply voltage of 2.5V is at 76μW. This number includes the power for various test structures that will be unnecessary for an industrial prototype, which is expected to operate below 20μW. A simple demonstrator of the reader is implemented on another PCB with a two digit hexadecimal LED display to show the telemetry data. This demo is associated with the BioCAS and the Sensory Systems track and is based on the publication [1] I. DEMONSTRATION SETUP The demonstrator consists of two PCBs: a prototype for the reader and a prototype for the implant as depicted in figure 1. The upper board is the reader prototype, powered by a 9V battery. It sends power on a 13.56MHz carrier to the implant prototype and receives telemetry data on the same link. The main component is a Xilinx CoolRunner II CPLD. The sensor value is displayed on a two digit hexadecimal LED display. The lower board is the implant prototype. Either a potentiometer or a air pressure sensor can be connected, in lieu of the targeted glucose sensor that is still under development. The implant prototype depicted contains a number of configuration switches which will be removed and the configuration will be hardwired for the demonstrator that will be brought to ISCAS 2010. This prototype’s approximate dimension will either be 2.5cm x 5cm, an area which is required by the ASIC package and the coil antenna, or merely 2cm x 2cm if the ASIC is wire bonded directly onto the PCB. II. VISITOR INTERACTION AND EXPERIENCE A. Asynchronous Pulse Density Modulation The implant does not perform a normal analog to digital conversion (ADC), but an analog to analog conversion, where the analog sensor value is translated into an analog/asynchronous inter pulse interval [1]. These pulses are conveyed to the reader over the inductive link by load modulation. The real ADC then simply consists of counting the pulses over a given interval. The decoded pulses can be observed on a portable oscilloscope and the correspondence of pulseintervals, the LED display and the ’sensor’ can be observed while the visitor tweaks the ’sensor’-potentiometer. B. Tuning the Transmitted Power If the reader is not close enough to the implant antenna, the implant is neither powered nor can it send data on the inductive link: the LED display shows 00. Only if the implant is moved close enough to the reader, will pulses be conveyed and a number be displayed. However, at first the power will not be sufficient for the ASIC’s internal regulator to operate properly. As a consequence, the pulse frequency will not truly reflect the sensor value. Moving closer, the power will become sufficient, but at some point the internally rectified voltage on the ASIC will become even too high and threaten to damage the ASIC. This is prevented by an internal reversible fuse (turning on an infinite load) which also sends pulses at a high frequency back to the reader. The reader display will indicate this by flashing digit points. A more advanced prototype reader shall achieve an optimal power transmission by gradually increaseing the carrier power until an over-voltage is signalled and then slightly reduce the power before each reading (once every 5 minutes).","PeriodicalId":91083,"journal":{"name":"IEEE International Symposium on Circuits and Systems proceedings. IEEE International Symposium on Circuits and Systems","volume":"14 1","pages":"2775"},"PeriodicalIF":0.0000,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Live demonstration: Inductive power and telemetry for micro-implant\",\"authors\":\"P. Häfliger\",\"doi\":\"10.1109/ISCAS.2010.5537016\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A prototype for a wireless implantable sensor system is demonstrated intended for a pill sized micro-implant for blood sugar monitoring. Power is sent and telemetry data received over a near field inductive link. The implant system is almost completely realized on a single CMOS ASIC, excepting three surface mounted capacitors, the coil antenna and the sensor. For this demonstration, the ASIC is packaged and mounted with the 4 other components on a PCB, and the glucose sensor is substituted with either a potentiometer or an atmospheric pressure sensor. In the targeted highly miniaturized implantable micro system all components (including antenna and sensor) will be integrated into a pill sized LTCC (low temperature cofired ceramics) package. The total implant power budget with the minimal supply voltage of 2.5V is at 76μW. This number includes the power for various test structures that will be unnecessary for an industrial prototype, which is expected to operate below 20μW. A simple demonstrator of the reader is implemented on another PCB with a two digit hexadecimal LED display to show the telemetry data. This demo is associated with the BioCAS and the Sensory Systems track and is based on the publication [1] I. DEMONSTRATION SETUP The demonstrator consists of two PCBs: a prototype for the reader and a prototype for the implant as depicted in figure 1. The upper board is the reader prototype, powered by a 9V battery. It sends power on a 13.56MHz carrier to the implant prototype and receives telemetry data on the same link. The main component is a Xilinx CoolRunner II CPLD. The sensor value is displayed on a two digit hexadecimal LED display. The lower board is the implant prototype. Either a potentiometer or a air pressure sensor can be connected, in lieu of the targeted glucose sensor that is still under development. The implant prototype depicted contains a number of configuration switches which will be removed and the configuration will be hardwired for the demonstrator that will be brought to ISCAS 2010. This prototype’s approximate dimension will either be 2.5cm x 5cm, an area which is required by the ASIC package and the coil antenna, or merely 2cm x 2cm if the ASIC is wire bonded directly onto the PCB. II. VISITOR INTERACTION AND EXPERIENCE A. Asynchronous Pulse Density Modulation The implant does not perform a normal analog to digital conversion (ADC), but an analog to analog conversion, where the analog sensor value is translated into an analog/asynchronous inter pulse interval [1]. These pulses are conveyed to the reader over the inductive link by load modulation. The real ADC then simply consists of counting the pulses over a given interval. The decoded pulses can be observed on a portable oscilloscope and the correspondence of pulseintervals, the LED display and the ’sensor’ can be observed while the visitor tweaks the ’sensor’-potentiometer. B. Tuning the Transmitted Power If the reader is not close enough to the implant antenna, the implant is neither powered nor can it send data on the inductive link: the LED display shows 00. Only if the implant is moved close enough to the reader, will pulses be conveyed and a number be displayed. However, at first the power will not be sufficient for the ASIC’s internal regulator to operate properly. As a consequence, the pulse frequency will not truly reflect the sensor value. Moving closer, the power will become sufficient, but at some point the internally rectified voltage on the ASIC will become even too high and threaten to damage the ASIC. This is prevented by an internal reversible fuse (turning on an infinite load) which also sends pulses at a high frequency back to the reader. The reader display will indicate this by flashing digit points. A more advanced prototype reader shall achieve an optimal power transmission by gradually increaseing the carrier power until an over-voltage is signalled and then slightly reduce the power before each reading (once every 5 minutes).\",\"PeriodicalId\":91083,\"journal\":{\"name\":\"IEEE International Symposium on Circuits and Systems proceedings. IEEE International Symposium on Circuits and Systems\",\"volume\":\"14 1\",\"pages\":\"2775\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2010-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IEEE International Symposium on Circuits and Systems proceedings. 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引用次数: 1
摘要
演示了一种用于血糖监测的药丸大小的微型植入物的无线植入式传感器系统的原型。电能通过近场感应链路发送,遥测数据通过近场感应链路接收。除了三个表面安装电容器、线圈天线和传感器外,植入系统几乎完全在单个CMOS ASIC上实现。在本演示中,ASIC与其他4个组件一起封装并安装在PCB上,葡萄糖传感器由电位器或大气压传感器代替。在目标高度小型化的可植入微系统中,所有组件(包括天线和传感器)将集成到一个药丸大小的LTCC(低温共烧陶瓷)封装中。最小供电电压为2.5V时,植入体总功率预算为76μW。这个数字包括了工业样机所需的各种测试结构的功率,预计其工作功率将低于20μW。在另一块PCB上实现了一个简单的阅读器演示,该演示带有一个两位数十六进制LED显示屏来显示遥测数据。该演示与BioCAS和感官系统相关,并以出版物[1]i为基础。演示设置演示器由两个pcb组成:如图1所示的读取器原型和植入物原型。上面的板是阅读器原型,由9V电池供电。它通过13.56兆赫的载波向植入原型发送能量,并在同一链路上接收遥测数据。主要部件是Xilinx CoolRunner II CPLD。传感器值显示在两位数十六进制LED显示屏上。下面的板是植入物原型。可以连接电位器或气压传感器,以代替仍在开发中的目标葡萄糖传感器。所描述的植入原型包含许多配置开关,这些开关将被移除,并且配置将被硬连接到将被带到ISCAS 2010的演示器中。该原型的大致尺寸将是2.5cm x 5cm,这是ASIC封装和线圈天线所需的面积,或者如果ASIC直接连接到PCB上,则仅为2cm x 2cm。2a .异步脉冲密度调制植入物不执行正常的模拟到数字转换(ADC),而是模拟到模拟转换,其中模拟传感器值被转换为模拟/异步脉冲间隔[1]。这些脉冲通过负载调制通过感应链路传送给阅读器。真正的ADC只是在给定的间隔内对脉冲进行计数。解码后的脉冲可以在便携式示波器上观察到,当参观者调整“传感器”电位器时,可以观察到脉冲间隔、LED显示屏和“传感器”的对应关系。B.调整发射功率如果读写器离植入物天线不够近,植入物既不通电,也不能在感应链路上发送数据:LED显示00。只有当植入物移动到离阅读器足够近的地方,才会传送脉冲并显示一个数字。然而,最初的权力将不足以让ASIC的内部监管机构正常运作。因此,脉冲频率将不能真实地反映传感器值。移动更近,功率将变得足够,但在某些点上ASIC上的内部整流电压将变得太高,并有可能损坏ASIC。这是防止内部可逆保险丝(打开无限负载),它也发送脉冲在高频回阅读器。阅读器显示器将通过闪烁的数字点来指示这一点。更先进的原型阅读器通过逐渐增加载波功率,直到信号过电压,然后在每次读取前(每5分钟一次)稍微降低功率来实现最佳功率传输。
Live demonstration: Inductive power and telemetry for micro-implant
A prototype for a wireless implantable sensor system is demonstrated intended for a pill sized micro-implant for blood sugar monitoring. Power is sent and telemetry data received over a near field inductive link. The implant system is almost completely realized on a single CMOS ASIC, excepting three surface mounted capacitors, the coil antenna and the sensor. For this demonstration, the ASIC is packaged and mounted with the 4 other components on a PCB, and the glucose sensor is substituted with either a potentiometer or an atmospheric pressure sensor. In the targeted highly miniaturized implantable micro system all components (including antenna and sensor) will be integrated into a pill sized LTCC (low temperature cofired ceramics) package. The total implant power budget with the minimal supply voltage of 2.5V is at 76μW. This number includes the power for various test structures that will be unnecessary for an industrial prototype, which is expected to operate below 20μW. A simple demonstrator of the reader is implemented on another PCB with a two digit hexadecimal LED display to show the telemetry data. This demo is associated with the BioCAS and the Sensory Systems track and is based on the publication [1] I. DEMONSTRATION SETUP The demonstrator consists of two PCBs: a prototype for the reader and a prototype for the implant as depicted in figure 1. The upper board is the reader prototype, powered by a 9V battery. It sends power on a 13.56MHz carrier to the implant prototype and receives telemetry data on the same link. The main component is a Xilinx CoolRunner II CPLD. The sensor value is displayed on a two digit hexadecimal LED display. The lower board is the implant prototype. Either a potentiometer or a air pressure sensor can be connected, in lieu of the targeted glucose sensor that is still under development. The implant prototype depicted contains a number of configuration switches which will be removed and the configuration will be hardwired for the demonstrator that will be brought to ISCAS 2010. This prototype’s approximate dimension will either be 2.5cm x 5cm, an area which is required by the ASIC package and the coil antenna, or merely 2cm x 2cm if the ASIC is wire bonded directly onto the PCB. II. VISITOR INTERACTION AND EXPERIENCE A. Asynchronous Pulse Density Modulation The implant does not perform a normal analog to digital conversion (ADC), but an analog to analog conversion, where the analog sensor value is translated into an analog/asynchronous inter pulse interval [1]. These pulses are conveyed to the reader over the inductive link by load modulation. The real ADC then simply consists of counting the pulses over a given interval. The decoded pulses can be observed on a portable oscilloscope and the correspondence of pulseintervals, the LED display and the ’sensor’ can be observed while the visitor tweaks the ’sensor’-potentiometer. B. Tuning the Transmitted Power If the reader is not close enough to the implant antenna, the implant is neither powered nor can it send data on the inductive link: the LED display shows 00. Only if the implant is moved close enough to the reader, will pulses be conveyed and a number be displayed. However, at first the power will not be sufficient for the ASIC’s internal regulator to operate properly. As a consequence, the pulse frequency will not truly reflect the sensor value. Moving closer, the power will become sufficient, but at some point the internally rectified voltage on the ASIC will become even too high and threaten to damage the ASIC. This is prevented by an internal reversible fuse (turning on an infinite load) which also sends pulses at a high frequency back to the reader. The reader display will indicate this by flashing digit points. A more advanced prototype reader shall achieve an optimal power transmission by gradually increaseing the carrier power until an over-voltage is signalled and then slightly reduce the power before each reading (once every 5 minutes).